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Fast dissolving oral films
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Fast dissolving oral films

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Oral films will give u good release of drug & relief from acute pain & problems...

Oral films will give u good release of drug & relief from acute pain & problems...

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Fast dissolving oral films Fast dissolving oral films Presentation Transcript

  • FAST DISSOLVING ORAL FILMS PRESENTED BY B.JAGADEESH BABU M.Pharm
  • OVER VIEW INTRODUCTION SPECIAL FEATURES GENERAL PROPERTIES FORMULATION METHOD OF PREPARATION EVALUATION TESTS ADVANTAGES & DISADVANTAGES CONCLUSION
  • INTRODUCTION These are the drug delivery systems which fastly disintegrate in mouth with H2O. It was first developed in 1970’s alternative to tablets & capsules. It consists of very thin oral strip which is placed on tongue & upon hydration it fastly releases drug into oral cavity.
  •  Thin elegant film Available in various sizes & shapes Unobstrusive Excellent mucoadhesion Rapid release
  • GENERAL PROPERTIES Thickness ranges from 1-10mm & it’s surface area is 1-20 cm². Its low dry tack allows for ease of handling & application. Its rapid hydration rate facilitates fast softening & absorption. 2mm thickness of film will take 5-10sec to start its disintegration.
  • FORMULATION DRUG WATER SOLUBLE POLYMER SUPER DISINTEGRANTS PLASTISIZER SURFACTANTS FLAVOURS COLOURS SWEETENING AGENTS SALIVA STIMIULATING AGENTS
  •  SOLVENT CASTING* SEMI-SOLID CASTING HOT MELT EXTRUSION SOLID DISPERSION EXTRUSION ROLLING METHOD
  • EVALUATION TESTS MORPHOLOGY STUDY SWELLING PROPERTY CONTACT ANGLE DISINTEGRATION MECHANICAL PROPERTIES 1. Tensile strength 2.Elastic modulus 3.% Elongation 4. Folding endurance
  •  Convenient dosing No water needed No risk of chocking Taste masking Enhanced stability First pass metabolism can be avoided
  •  Easily fragile & brittle. Special package for protection during storage & transportation.
  •  These are having several advantages over conventional dosage forms like ODT, TABLETS, CAPSULES ,IV etc., so they are of great importance during the emergency cases such as allergic reations & asthamatic attacks.