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Bd japan poster_iii

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  • 1. Laser Management of Resistant Oral Ulcers in Patients with Behçets Disease: A Pilot Study. P3-2-063 Samir H. Assaad-Khalil 1; Islam M. Kassem2 Department of Internal Medicine 1, Faculty of Medicine & Department of Cranio-maxillary-facial Surgery 2, Faculty of Dentistry, Alexandria University, Alexandria, EGYPT. BACKGROUND PATIENT # 1 RESULTS (Cont.) Figure (2): Frequency of Diabetic Complications in Type Behçet’s disease is a chronic 2 Diabetic Patients inflammatory disorder affecting 50% multiple systems and may have 45% 46% serious implications on patients’ quality of life. In fact, resistant oral 40% ulcers can jeopardize normal life 35% style. 31.80% 30% 25% OBJECTIVE Preoperative lesion Infiltration of local anesthesia 20% 18.30% 15.90% The aim of the present study 15% has been to assess the efficacy 10% 9.70% and safety of the use of Carbon dioxide laser in management of 5% 3.10% resistant intraoral ulcers in 0% patients with Behçet’s Disease Subjects Table IX: Relative Frequency of the Cause of Hospitalization Due to Diabetic Complications During the Last 3 Months in Type 2 Diabetic Patients* The present study included 15 Lesion after application of CO2 laser After one week patients (10 males 5 females) with Behçet’s disease, diagnosed according to the International Classification Criteria, suffering Size Pre op Post op Time of from recurrent resistant oral Patient Age Gender Site Number of ulcers mm pain pain surgery Reccurence 1 32 M Cheek Single 20 5 2 15 no ulcerations and dysphagia failing 2 52 M Lower lip Single 25 4 1 10 no to respond to conventional medical 3 25 F Tongue Single 15 4 2 12 yes therapy. 4 33 F Tongue Multiple 20 5 1 19 no 5 43 M Cheek Single 30 4 1 31 no 6 40 M Tongue Single 45 5 1 10 no Four patients showed multiple Alveolar 7 46 M mucosa Single 35 4 1 13 no ulcers, the rest single ulcer. The 8 9 60 52 M M Lower lip Cheek Single Multiple 25 30 4 5 2 3 11 15 no no sites of the ulcers were variable After 3 months After 6 months 10 38 F Tongue Single 45 4 2 8 no including cheeks, alveolar mucosa, Alveolar 11 56 M mucosa Single 25 4 1 8 no tongue, and lips. The ulcers size 12 13 45 39 M F Cheek Lower lip Multiple Multiple 30 45 5 5 2 1 7 6 no no varied from 15 to 45 mm2. PATIENT # 2 14 62 M Cheek Single 40 4 3 7 yes 15 29 F Cheek Single 30 3 1 9 no Methods Carbon dioxide laser has been used to vaporize the ulcers with caution to avoid bleeding. All patients were followed up to CONCLUSION CONCLUSION evaluate the efficacy and safety of the used intervention. This pilot intervention study Preoperative cheek lesions Preoperative throat lesions suggests that Carbon dioxide laser This included the impact on technique can be considered as an pain, effect on healing, effect on effective and safe therapeutic recurrence and on the quality of modality for the management of life (The SF-36 QoL Scale and the resistant oral ulcers particularly Washington QoL in Oral Cancer). associated with dysphagia and pain in patients with Behçet’s RESULTS disease. A significant improvement of all CONTACT INFORMATIONS studied parameters has been observed. A 50% improvement in Prof. Samir Helmy ASSAAD-KHALIL both the pain score and QoL Address: Department of Internal Medicine, Scales. Only 2 patients out of 15 Post operative cheek lesions Post operative throat lesions Faculty of Medicine, Alexandria University, Alexandria, EGYPT. showed recurrence during a six Phone: +20-1222197789 months follow up period. Fax: +203-4833321 Email: assaadkhalil@hotmail.comPOSTER TEMPLATE BY:www.PosterPresentations.com