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IN WOMEN, WEIGHT LOSS INCREASES THE RISK FORGALLSTONE DISEASE MORE       THAN OBESITY        Authors      Kapantais Efthym...
Department of Endocrinology,      Diabetes & Metabolism        Athens        Medical Centre Hospital        Athens        ...
Introduction Obesity is considered to be an important risk factor for gallstone disease. Other principal risk factors are...
Subjects       1632 Females  Age >20 yrs  No use of contaceptives  No history of aemolytic anaemiasHistory of cholecyst...
MethodsSeparation into 3 groups   1. According to previous weight   reduction    noTry: never trying loosing weight    <...
Results               50           %               40               30               20                                   ...
Results                                                                60                                                 ...
Conclusion In womenWeight reducing regimens seem toincrease the risk for gallstonedisease more than obesity per se.This...
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1997 bile.8th eco

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Transcript of "1997 bile.8th eco"

  1. 1. IN WOMEN, WEIGHT LOSS INCREASES THE RISK FORGALLSTONE DISEASE MORE THAN OBESITY Authors Kapantais Efthymios Mortoglou Anastasios Candiloros Harilaos Venaki Evangelia Georgiadou Elli
  2. 2. Department of Endocrinology, Diabetes & Metabolism Athens Medical Centre Hospital Athens GREECE8th European Congress on Obesity Dublin (Ireland) 18-21 June 1997
  3. 3. Introduction Obesity is considered to be an important risk factor for gallstone disease. Other principal risk factors are age, female gender and childbearing. Purpose To investigate if obesity per se ORPrevious weight reduction regimen are responsible for for gallstone disease.
  4. 4. Subjects 1632 Females  Age >20 yrs  No use of contaceptives  No history of aemolytic anaemiasHistory of cholecystectomy in the past or Known cholelithiasis
  5. 5. MethodsSeparation into 3 groups 1. According to previous weight reduction  noTry: never trying loosing weight  <10kg: loss in the past less than 10 kg  >10kg: loss in the past more than 10 kg at least once 2. According to BMI  BMIGR1: BMI < 30  BMIGR2: BMI 30 - 40  BMIGR3: BMI > 40 3. According to age  AGEGR1: age 21 - 35  AGEGR2: age 36 - 50  AGEGR3: age > 50
  6. 6. Results 50 % 40 30 20 >10 Kgr 10 <10 Kgr 0 NoTry 0 1 2 3 Children Females, age 36 - 50, BMI 30 - 40 Total Prevalence of known cholelithiasis: 120/1632, 7.35 %
  7. 7. Results 60 % 40 20 0 0 > 10 K gr 1 Children < 10 K gr 2 N oT ry Females, age >50, BMI >40 Total Prevalence of known cholelithiasis: 120/1632, 7.35 %
  8. 8. Conclusion In womenWeight reducing regimens seem toincrease the risk for gallstonedisease more than obesity per se.This risk increases relatively tototal weight loss.
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