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Differences among Diabetic &
      Non-Diabetic persons, concerning
       Body Fat Distribution assessed
                     by
               CONICITY INDEX.


6th European Congress on Obesity 1995
E. Kapantais, E. Papadimitriou,
                    K. Vendiadi, E. Manglara,
                   K. Kofotzouli, M. Marangos
                      and N. Katsilambros.

                  1st Dpt. Propaedeutic Medicine
                 Athens’ University Medical School
                     “Laikon” General Hospital
                         Athens - GREECE



6th European Congress on Obesity 1995
Background:
       It is well established that excess body fat around the abdomen is
      related to several metabolic disorders and mainly to type-2 Diabetes
      Mellitus (NIDDM).
       The most accurate technique for assessing abdominal fat mass, Axial
      Computerized Tomography (ACT), is costly and time-consuming.
       Anthropometry could be a valid alternative to ACT for the evaluatin of
      fat distribution. However, current anthropometric indicators of obesity
      have several limitations.
       CONICITY INDEX implies that abdominal obesity is modelled as the
      progression of a body from cylindrical shape toward the shape of 2 cones
      with a common base at the waist level. This geometric approach expressed
      with the formula: CONICITY INDEX = abdominal girth
                                         0.109(weight/height)½
       With this new index, the abdominal girths of persons of the same
      height and weight are referred to the same standard value for comparison.


6th European Congress on Obesity 1995
Aim:

        To assess the Conicity Index values
             in a group of NIDDM, aged 50-65
             years, as compared to Controls.

           To study the correlation between
                 CONICITY INDEX and WHR
                  in NIDDM and Controls.

6th European Congress on Obesity 1995
SUBJECTS & METHODS:
       Subjects: Age: 50 - 65 years.
                   86 Controls (53 males - 33 females) &
                 64 Type-2 Diabetics (33 males - 31 females).

       Measurements:
          Weight, Height, Abdominal Girth,
          Waist circumference, Hip circumference.
       Calculation:
        1) BMI= Weight / Height2
        2) WHR= Waist circumference / Hip circumference
        3) CONICITY INDEX=      Abdominal Girth
                           0.109* (Weight / Height)½

6th European Congress on Obesity 1995
RESULTS:


               Males : 1.316 ± 0.081
                         M ± SD
              Females : 1.252 ± 0.112

                                             F      M
                          Males and Females
                      CONICITY INDEX mean values.


6th European Congress on Obesity 1995
Mean BMI values.
                                                          * p =0.025
            30                                                  *
            29                                    29.39


            28
                   28.25           28.3

            27


            26                                                   26.66


            25


            24
                             MALES                  FEMALES
                  NIDDM1       Controls ### °×Ó·›Î˜: ¢È·‚ËÙÈ΀˜ - 4M¿ÚÙ×Ú˜
             AÓ‰ Ú˜: ¢È·‚ËÙÈÎÔ›    2
                                - M¿ÚÙ×Ú˜ ## NIDDM
                                                 3             Controls

6th European Congress on Obesity 1995
Mean Conicity Index & WHR values
               WHR         CONICITY INDEX                    * p=0.002
                                                     *         § p=0.001



                                                 §
                                                 §




                    MALES:                       FEMALES:
              NIDDM   # Controls         NIDDM    # Controls


6th European Congress on Obesity 1995
Conicity Index values,
                   in Males and Females, NIDDM and Controls.


                            MALES                   FEMALES
             1.6                           1.5

                        *
             1.5
                                *          1.4


             1.4
                                           1.3

             1.3

                                           1.2
             1.2
                                *
                        *
                        *
                                           1.1
             1.1

                                                            *
             1.0                           1.0
                        0       1                     0     1

                    Controls # NIDDM             Controls # NIDDM



6th European Congress on Obesity 1995
Correlation between Conicity Index & WHR
                                  in Males and Females.

                         r=0.78, p=0.000                                     r=0.74, p=0.000
            1.2                                                  1.1




            1.1
                                                                 1.0
        W                                                    W
        H   1.0
                                                             H
                                                                 0.9
        R   0.9
                                                             R
                                                                 0.8
            0.8




            0.7                                                  0.7
                  1.0    1.1   1.2   1.3   1.4   1.5   1.6             1.0    1.1    1.2   1.3   1.4   1.5


                         Conicity Index                                      Conicity Index
                               MALES                                                FEMALES


6th European Congress on Obesity 1995
Correlation between Conicity Index and WHR
                       in Females with NIDDM & Controls.


                         r=0.58, p=0.001                                  r=0.80, p=0.000
             1.0                                              1.1




                                                              1.0

             0.9
         W                                                W
         H                                                H   0.9


         R   0.8
                                                          R
                                                              0.8




             0.7                                              0.7
                   1.0    1.1     1.2   1.3   1.4   1.5             1.0   1.1    1.2   1.3   1.4   1.5



                         Conicity Index                                   Conicity Index
                                Controls                                        NIDDM


6th European Congress on Obesity 1995
Correlation between Conicity Index and WHR
                         in Males with NIDDM & Controls.

                         r=0.87, p=0.000                                    r=0.66, p=0.000
            1.2                                                 1.1




            1.1



        W   1.0
                                                            W   1.0



        H                                                   H
        R   0.9                                             R   0.9


            0.8




            0.7                                                 0.8
                  1.0   1.1   1.2   1.3   1.4   1.5   1.6             1.0   1.1    1.2   1.3   1.4   1.5



                        Conicity Index                                      Conicity Index
                              Controls                                            NIDDM



6th European Congress on Obesity 1995
CONCLUSIONS:
                 In persons aged 50-65 years:

               Women with NIDDM present
                 similar Body Fat Distribution,
                       as men with NIDDM.

                         Conicity Index is
                     closely related to WHR.

6th European Congress on Obesity 1995

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Differences in Body Fat Distribution Between Diabetic and Non-Diabetic Assessed by Conicity Index

  • 1. Differences among Diabetic & Non-Diabetic persons, concerning Body Fat Distribution assessed by CONICITY INDEX. 6th European Congress on Obesity 1995
  • 2. E. Kapantais, E. Papadimitriou, K. Vendiadi, E. Manglara, K. Kofotzouli, M. Marangos and N. Katsilambros. 1st Dpt. Propaedeutic Medicine Athens’ University Medical School “Laikon” General Hospital Athens - GREECE 6th European Congress on Obesity 1995
  • 3. Background:  It is well established that excess body fat around the abdomen is related to several metabolic disorders and mainly to type-2 Diabetes Mellitus (NIDDM).  The most accurate technique for assessing abdominal fat mass, Axial Computerized Tomography (ACT), is costly and time-consuming.  Anthropometry could be a valid alternative to ACT for the evaluatin of fat distribution. However, current anthropometric indicators of obesity have several limitations.  CONICITY INDEX implies that abdominal obesity is modelled as the progression of a body from cylindrical shape toward the shape of 2 cones with a common base at the waist level. This geometric approach expressed with the formula: CONICITY INDEX = abdominal girth 0.109(weight/height)½  With this new index, the abdominal girths of persons of the same height and weight are referred to the same standard value for comparison. 6th European Congress on Obesity 1995
  • 4. Aim:  To assess the Conicity Index values in a group of NIDDM, aged 50-65 years, as compared to Controls.  To study the correlation between CONICITY INDEX and WHR in NIDDM and Controls. 6th European Congress on Obesity 1995
  • 5. SUBJECTS & METHODS:  Subjects: Age: 50 - 65 years. 86 Controls (53 males - 33 females) & 64 Type-2 Diabetics (33 males - 31 females).  Measurements: Weight, Height, Abdominal Girth, Waist circumference, Hip circumference.  Calculation: 1) BMI= Weight / Height2 2) WHR= Waist circumference / Hip circumference 3) CONICITY INDEX= Abdominal Girth 0.109* (Weight / Height)½ 6th European Congress on Obesity 1995
  • 6. RESULTS: Males : 1.316 ± 0.081 M ± SD Females : 1.252 ± 0.112 F M Males and Females CONICITY INDEX mean values. 6th European Congress on Obesity 1995
  • 7. Mean BMI values. * p =0.025 30 * 29 29.39 28 28.25 28.3 27 26 26.66 25 24 MALES FEMALES NIDDM1 Controls ### °×Ó·›Î˜: ¢È·‚ËÙÈ΀˜ - 4M¿ÚÙ×Ú˜ AÓ‰ Ú˜: ¢È·‚ËÙÈÎÔ› 2 - M¿ÚÙ×Ú˜ ## NIDDM 3 Controls 6th European Congress on Obesity 1995
  • 8. Mean Conicity Index & WHR values  WHR  CONICITY INDEX * p=0.002 * § p=0.001 § § MALES: FEMALES: NIDDM # Controls NIDDM # Controls 6th European Congress on Obesity 1995
  • 9. Conicity Index values, in Males and Females, NIDDM and Controls. MALES FEMALES 1.6 1.5 * 1.5 * 1.4 1.4 1.3 1.3 1.2 1.2 * * * 1.1 1.1 * 1.0 1.0 0 1 0 1 Controls # NIDDM Controls # NIDDM 6th European Congress on Obesity 1995
  • 10. Correlation between Conicity Index & WHR in Males and Females. r=0.78, p=0.000 r=0.74, p=0.000 1.2 1.1 1.1 1.0 W W H 1.0 H 0.9 R 0.9 R 0.8 0.8 0.7 0.7 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.0 1.1 1.2 1.3 1.4 1.5 Conicity Index Conicity Index MALES FEMALES 6th European Congress on Obesity 1995
  • 11. Correlation between Conicity Index and WHR in Females with NIDDM & Controls. r=0.58, p=0.001 r=0.80, p=0.000 1.0 1.1 1.0 0.9 W W H H 0.9 R 0.8 R 0.8 0.7 0.7 1.0 1.1 1.2 1.3 1.4 1.5 1.0 1.1 1.2 1.3 1.4 1.5 Conicity Index Conicity Index Controls NIDDM 6th European Congress on Obesity 1995
  • 12. Correlation between Conicity Index and WHR in Males with NIDDM & Controls. r=0.87, p=0.000 r=0.66, p=0.000 1.2 1.1 1.1 W 1.0 W 1.0 H H R 0.9 R 0.9 0.8 0.7 0.8 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.0 1.1 1.2 1.3 1.4 1.5 Conicity Index Conicity Index Controls NIDDM 6th European Congress on Obesity 1995
  • 13. CONCLUSIONS: In persons aged 50-65 years:  Women with NIDDM present similar Body Fat Distribution, as men with NIDDM.  Conicity Index is closely related to WHR. 6th European Congress on Obesity 1995