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Residual monomer --it’s cytotoxicity /certified fixed orthodontic courses by Indian dental academy

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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.

Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078

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  • 1. RESIDUAL MONOMER--IT’S CYTOTOXIC POTENTIAL INDIAN DENTAL ACADEMY Leader in continuing dental education www.indiandentalacademy.com www.indiandentalacademy.com
  • 2. INTRODUCTION www.indiandentalacademy.com
  • 3. RESIDUAL MONOMER  The conversion of monomers to polymers – un reacted monomers -- residual monomers  Residual cause monomer has the potential to Irritation Inflammation Allergic response & Stomatitis Angular cheilitis www.indiandentalacademy.com
  • 4. ALLERGIC STOMATITIS www.indiandentalacademy.com
  • 5. ANGULAR CHEILITIS www.indiandentalacademy.com
  • 6. RESIDUAL MONOMER SIGNS AND SYMPTOMS.  Erythema  Erosion of oral mucosa  Burning sensation on mucosa and tongue www.indiandentalacademy.com
  • 7. RESIDUAL MONOMER  Allergic reaction few to several hours  Allergic contact stomatitis . Delayed type of hypersensitivity ---Hypersensitivity of mucosa and skin. www.indiandentalacademy.com
  • 8. RESIDUAL MONOMER  In 1956 ‘Fisher’ identified methyl methacrylate monomers as the cause of allergic dermatitis of 4 dentists and dental laboratory technicians. www.indiandentalacademy.com
  • 9. RESIDUAL MONOMER Biocompatibility Heat cure more than self cure Allergic response Self cure more than heat cure www.indiandentalacademy.com
  • 10. RESIDUAL MONOMER CONTACT DERMATITIS  Other side effects 1.Contact dermatitis 2.Respiratory distress 3.Cardiovascular effects www.indiandentalacademy.com
  • 11. RESIDUAL MONOMER  Parameters to monitor cytotoxic effects of dental materials are inhibition of cell growth, cytolysis, changes in the metabolic activity ( Janaina Habib Jorge and E . Teresinha et al; Effect of post polymerization heat treatments on the cytotoxicity of two denture base acrylic resins Appl Oral Sci; 2006;14(3);203-7 ) www.indiandentalacademy.com
  • 12. RESIDUAL MONOMER  “Smith ”found that in self cured acrylic resins different areas of denture appeared to have different percentage of residual monomer due to the difference in thickness of material. www.indiandentalacademy.com
  • 13. RESIDUAL MONOMER  An acrylic resin which contains high levels of residual monomer may exhibit low mechanical strength. ( A. M. Fletcher and S. Purnaveja et al ;The level of residual monomer in self curing denture base materials Dent Res 1983 ;62 ( 2 );118-120 ) www.indiandentalacademy.com
  • 14. FACTORS THAT INFLUENCE CYTOTOXICITY OF DENTURE BASE ACRYLIC RESINS  Polymer to monomer ratio  Type of polymerization cycle  Method of polymerization  Storage time and water immersion www.indiandentalacademy.com
  • 15. POLYMER TO MONOMER RATIO  ‘Kedjarune’ et al the more monomer added to the mixture the greater the amount of residual monomer and therefore more potential for cytotoxicity.  Resins prepared with a high proportion of polymer to monomer ratio ( 5:3) resulted in significantly lower levels of residual monomer as compared to those prepared with a lower ratio(4:3) www.indiandentalacademy.com
  • 16. POLYMERIZATION CYCLE Extended polymerization time—low levels of residual monomer—less cytotoxicity Harrison and Huggett tests 7hr at 700c 1hr at 1000c Maximum conversion of residual monomer www.indiandentalacademy.com 7hr at 600c 5min at 900c High residual monomer
  • 17. POLYMERIZATION METHOD  Cytotoxicity Auto polymerizing > Heat cure >Microwave www.indiandentalacademy.com
  • 18. WATER STORAGE  Water storage for 24 hrs  Longer storage--less cytotoxicity  50c for 60 min—reduce monomer—less cytotoxicity ( Janaina Habib Jorge DDS, and E.Teresinha et al; cytotoxity of denture base acrylic resins: a literature review; J Prosthet dent 2003;90:190-3) www.indiandentalacademy.com
  • 19. CONCLUSION www.indiandentalacademy.com
  • 20. ACKNOWLEDGEMENTS        Dr. P. MAHESH. M.D.S.(PROFF& HOD) Dr. P. SRINIVASA RAO.M.D.S.( ASS.PROFF) Dr. SASI DEEPTHI REDDY.M.D.S. Dr. KUMAR. M.D.S. Dr. DILEEP NAG.M.D.S. Dr. PAVAN.M.D.S. Dr. SUDHEER.M.D.S. www.indiandentalacademy.com
  • 21. THANK YOU www.indiandentalacademy.com

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