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Go camp 2010_cacao

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  • 1. CACAO Community Assessment of Community Annotation with Ontologies i.e. Undergrads doing functional annotation using Gene Ontology
  • 2. Basic problem for Community Annotation • People are enthusiastic in theory but too busy in practice • Our approach: annotation as a teaching activity provides incentives to participate (for some)
  • 3. Student curation focused on IEA validation • Without much experience with GO, students can still – look for experiments to support IEA or ISS annotations – deprecate incorrect annotations
  • 4. CACAO 0.1 • 20 students volunteered • 16 students completed it ~ 2.5 weeks later • Mini GO camp – meeting 1: Survey/GO overview – meeting 2: annotate 2 papers as group • Paper 1: everyone • Paper 2: divided into teams • Each team got a list of E. coli genes; annotation on EcoliWiki • meeting 3: Survey/Evaluate annotations/announce winners – Peer review by competition = Teams steal points by correcting annotations
  • 5. Results • Got many more annotations than we expected • Quality was not bad • Survey provided insight into student strategies – Conversion of non-GO functional annotations – new annotations
  • 6. Lessons/Refinements • Students loved the competition • Need to tweak the training – More on finding appropriate papers • Need multiple rounds – Students did not use the mentors enough • More time for challenges • Better wiki tools for mentors/judges to track student annotation
  • 7. Scoreboard extension
  • 8. Scoreboard extension
  • 9. CACAO 1.0 • Recruiting participants for Fall 2010 – ASM, ASMCUE, AgBase, … – Not just E. coli!! • We will offer – Content related to GO/genomics/function – Support for assessment • Rubrics, surveys etc. – Plans for possible publications • Incentives – Credit for innovative teaching on their campuses – NSF broader impacts – inter-institution teams for recruiting