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Figure 1

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  • 1. Figure 1. Renal pathology in Fabry disease. (A) Glomerulus showing extensive inclusion bodies of glycolipid in podocytes (arrowhead), and mild mesangial widening (PAS stain;magnification, x80). (B) Plastic embedded tissue showing in-site deposition of glycolipidin glomerular podocytes (arrowhead; toluidine blue stain; magnification, x80). (C) Plastic embedded renal tissue demonstrating glycolipid inclusion bodies in distal tubules (asterisk), with relative sparing of proximal tubules, and interstitial fibrosis (toluidine blue stain; magnification, x80). (D) Deposition of glycolipid in endothelial cells of peritubular capillaries (asterisk; toluidine blue stain; magnification, x200). (E) Urine showing vacuolated urinary epithelial cells (oval fat bodies) in a Fabry patient(Papanicolaou stain; magnification, x160). Figure modified with permission from Branton et al. (14).
  • 2. The kidneys are responsible for removing wastes from the body, regulating electrolytebalance and blood pressure, and stimulating red blood cell production.
  • 3. --http://groups.google.com.sa/group/ksa14/boxsubscribe

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