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    Essential trace elements for humans, animals and    plants    Naturally present in some foods, added to others,    a...
    Average Adult Body: 1.4-2.5 g Zn     Typically found in bone, prostate, choroid of    the eye    90% total body zin...
    An essential component of several metalloenzymes    Development of male reproductive functions and formation of    t...
    Hydrolization    Zinc must separate from the amino acids which takes place in the stomach    Absorption    It occurs...
Absorption Inhibitors    Absorption of zinc decreases with fiber, phytate, copper, calcium,    phosporus, cadmium, casein...
The major sources of zinc are found in animal foods like:o  Milko  Beef meato  Livero  Oysterso  Eggso  Crimni mushroomso ...
Zinc deficiency is characterized by:    retardation    loss of appetite    impaired immune function    alopecia    di...
    People with gastrointestinal and other diseases    Vegetarians    Pregnant and lactating women    Older infants wh...
    Acute adverse effects of high zinc intake include nausea,    vomiting, loss of appetite, abdominal cramps, diarrhea, ...
Zinc in the Body
Zinc in the Body
Zinc in the Body
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Zinc in the Body

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Absorption,Utilization,Sources, Deficiency, Toxicity

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Transcript of "Zinc in the Body"

  1. 1.  Essential trace elements for humans, animals and plants Naturally present in some foods, added to others, and available as a dietary supplement Involved in numerous aspects of cellular metabolism Required for the catalytic activity of approximately 100 enzymes
  2. 2.  Average Adult Body: 1.4-2.5 g Zn Typically found in bone, prostate, choroid of the eye 90% total body zinc are found in the bone and skeletal system 0.5% total body zinc are found in the blood Plasma zinc level: 75 – 120 ug/dL
  3. 3.  An essential component of several metalloenzymes Development of male reproductive functions and formation of testosterone An accelerator of wound healing and for a normal sense of taste Vital for the immune system Vital for growth and cell division Vital for vision
  4. 4.  Hydrolization Zinc must separate from the amino acids which takes place in the stomach Absorption It occurs along the upper jejunum which comes from food or from enteropancreatic circulation of endogenous zinc, Zinc may pass to the enterocytes by passive diffusion (at very high intestinal concentrations) Absorption Enhancers The presence of substances that bind with zinc and help carry it across to the enterocytes enahnce zinc absorption Presence of glucose, lactose, soy protein, meat protein, Vitamin C, glutamate, citrate Amino acids: histidine, cysteine, methionine
  5. 5. Absorption Inhibitors Absorption of zinc decreases with fiber, phytate, copper, calcium, phosporus, cadmium, casein Transport and Storage It is carried through the bloodstream bound to albumin and taken to the liver before redistribution to other tissues. Zinc that is not needed immediately is stored throughout the body. Excretion It is excreted through feces. Significant amounts are lost from the urine, hair loss, and sweating.
  6. 6. The major sources of zinc are found in animal foods like:o Milko Beef meato Livero Oysterso Eggso Crimni mushroomso Spinacho Pumpkin seedso Green Peaso Nutso Legumeso Whole grain cerealso Wheat and branNote: Availability is less in plants sources.. Food processing removes a large proportion of zinc as well as other trace elements.
  7. 7. Zinc deficiency is characterized by: retardation loss of appetite impaired immune function alopecia diarrhea delayed sexual maturation Impotence in males eye and skin lesions
  8. 8.  People with gastrointestinal and other diseases Vegetarians Pregnant and lactating women Older infants who are exclusively breastfed People with sickle cell disease Alcoholics
  9. 9.  Acute adverse effects of high zinc intake include nausea, vomiting, loss of appetite, abdominal cramps, diarrhea, and headaches. It has an effect of decrease in HDL-cholesterol in adult males. Associated with inhalation of zinc chloride from industrial pollution, causing loss of iron from the liver and a loss of copper.
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