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Cell Metabolism
Cell Respiration (Metabolism) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cellular Metabolism Metabolism  – all chemical reactions that occur in the body  Two types of metabolic reactions Anabolic ,[object Object]
Goal of Cell Respiration-Make ATP
Anabolic Anabolism provides the substances needed for cellular growth and repair  ,[object Object],[object Object],[object Object]
 
Catabolic Catabolism breaks down larger molecules into smaller ones ,[object Object],[object Object],[object Object],[object Object]
Control of Metabolic Reactions Enzymes-  all are proteins ,[object Object],[object Object],[object Object],[object Object]
Do not make anything happen that could not happen on its own Enzymes can be reused over and over Same enzymes catalyses the forward and reverse reactions.  They are  very  specific
 
 
Control of Metabolic Reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Control of Metabolic Reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Energy for Metabolic Reactions ,[object Object],[object Object],[object Object],[object Object]
Cellular Respiration ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Glycolysis  ,[object Object],[object Object],[object Object]
Citric Acid Cycle ,[object Object],[object Object],[object Object],[object Object],[object Object]
The Goal is the production of NADH and FADH2 for use in the ETC—they are electron carriers
ETC ,[object Object],[object Object],[object Object],[object Object],[object Object]
Oxygen if the Final Electron Acceptor Why do we Breath??
 
Summary of Catabolism of Proteins, Carbohydrates, and Fats 4-21
Carbohydrate Storage ,[object Object],[object Object],[object Object],[object Object]
Regulation of Metabolic Pathways Turned off when their product is in strong supply Works by supply and demand  4-23
Nucleic Acids and  Protein Synthesis Gene  – segment of DNA that codes for one protein Genome  – complete set of genes
The Central Dogma ,[object Object],[object Object],[object Object]
Structure of DNA ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
RNA Molecules mRNA rRNA tRNA
Protein Synthesis (Transcription and Translation)  ,[object Object],[object Object],[object Object]
 
 
Translation
Overview: Protein Synthesis
DNA Replication
Mutations Mutations  – change in genetic information ,[object Object],[object Object],[object Object],May or may not change the protein Some good some bad
Clinical Application Phenylketonuria PKU ,[object Object],[object Object],[object Object]

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Cell metabolism