Once cleaning begins inside the enclosure: Start with cleaning removable top panel. Work from left to right, wiping back to front.
Remove upper panel – slight lift at the rear of panel and slide back. Drop front edge just below front lip and slide forward to clear rear panel. Once clear, lower back panel at an angle and bring to base. Rest front edge of panel on front, side airfoils. ** During the removal process, be careful to not raise panel too high as blower can create suction that can pull panel upwards to obstruct filter.
Wipe leading edge from left to right. Then on top side, wipe from front to back. Stand panel up and wipe reverse side from top to bottom. Remove cleaned panel from enclosure.
Wipe down front of rear baffle (Use EasyClean ™ 360 Isolator Cleaning Tool) to reach beyond arms length. The cleaning tool cover should be changed when visibly soiled and between surface cleanings.
Remove rear baffle and rest on front, side airfoils. Start on one side and wipe from front to back with 10% overlap with each pass. Remove clean baffle from enclosure.
Clean all upper surfaces (do not disturb HEPA filter).
Next clean back panel either by wiping from top to bottom with wiper or by using EasyClean ™ 360 Isolator Cleaning Tool. The cleaning tool cover should be changed when visibly soiled and between surface cleanings.
Use smooth strokes top to bottom applying light pressure.
Clean both the right and left side of the enclosure. Start at back and move forward, wiping from top to bottom. Be sure to wipe down any hooks or screwheads. Also wipe down side airfoils.
Clean the rear baffle supports. For this purpose a cleanroom swab may also be used.
For sterile or USP <797> applications a more rigorous cleaning routine is required and the use of “non-shedding” polyester wipers is recommended. For sterile or aseptic applications it is also recommended that any cleaning product used is sterile.
USP <797> Cleaning Requirement Critical Site Minimum Frequency Monthly Storage shelves Monthly Ceilings Monthly Walls Daily Floors Daily Counters and work surfaces
At the beginning of each shift.
Before each batch.
Not longer than 30 minutes after the previous surface disinfection ( during ongoing compounding activities ).