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Transcript

  • 1. About this lecture
    • Composition of Blood
    • Plasma make up and roles
    • Various cell types, origin and roles
    • Red blood cells, hemoglobin & iron metabolism
  • 2. Blood Components: Plasma Transports Solutes
    • Water, ions, trace elements
    • Gasses: O 2 & CO 2
    • Organic Molecules
      • Glucose
      • N–wastes
      • Proteins
      • Antibodies
      • Hormones
  • 3. Blood Components: Plasma Transports Solutes Figure 16-1: Composition of blood
  • 4. Blood Components: "Blood Count" – % of Each Component Figure 16-2: The blood count
  • 5. Blood Components: Cells
    • Erythrocytes
      • Red Blood Cells (RBC)
      • O 2 & CO 2 transport
    • White Blood Cells (WBC)
      • Immune defense
      • Phagocytosis
    • Platelets: clotting
  • 6. Hematopoiesis: Blood Cell Formation
    • Mostly in bone marrow from stem cells
    • Rate regulated by cytokines & growth factors
  • 7. Hematopoiesis: Blood Cell Formation Figure 16-3: Hematopoiesis
  • 8. Focus on RBCs: Figure 16-5c: Bone marrow
  • 9. Focus on RBCs: Figure 16-7a, b: Bone marrow
  • 10. Iron Metabolism: Key to Hemoglobin O 2 Transport Figure 16-8: Iron metabolism
  • 11. Some Diseases of RBCs and O 2 Transport Table 16-3: Causes of Anemia