Basic pharmacology   hamza
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Basic pharmacology hamza

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Basic pharmacology   hamza Basic pharmacology hamza Presentation Transcript

  • Hamza HemalRadiant Pharmaceuticals Ltd.
  • Brand Name•Trade name•Given by the Manufacturer company•To distinguish products from each other.Example:ACOS (Radiant)ZIMAX ( Square)
  • Generic NameOfficial medical name for the active ingredient of the medicine.Example:AzithromycinEsomeprazole Hamza
  • API• Active Pharmaceutical Ingredient• Any component that provides pharmacological activity Hamza
  • Dosage Form• A dosage form is the physical form in which a drug is produced and dispensed.• Example: – Tablet, – Capsule, – PFS (Powder for Suspension) – Injection Hamza
  • StrengthAmount of the active ingredient is present in each dosage. Example: 500mg Tablet 200mg/5ml PFS Hamza
  • Brand Name Strength Generic NameDosageForm Hamza
  • COGS• Cost of Goods sold• Raw material + Packaging Material + Utility cost + Per head costTP•Trade Price•COGS + ProfitInvoice PriceTP+ VATMRPMaximum Retail Price HamzaTP+ VAT+ Chemist Profit
  • Pharmacodynamicswhat the drug does to the body Pharmacokineticswhat the body does to the drug Hamza
  • Bioavailability• Amount of drug that present in blood after administration.• INTRAVENOUS Route- Bioavaiability 100% Hamza
  • Peak Plasma concentration, CmaxThe maximum plasma concentration of the drug achieved in blood after a doseTmaxThe time when themaximum plasmaconcentration (Cmax) isreached. Hamza
  • Plasma half life/Elimination Half Life, T1/2Time necessary for the drug to be reduced to half of its plasma concentration 11 10 9 8 7 6 5 4 3 2 1 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 T1/2
  • Area Under the Curve (AUC)The area under the plot of plasma concentration of drug against time after drug administration.
  • MEC• Minimum Effective Concentration• The smallest concentration of a drug that will induce the desired pharmacological effect MIC• Minimum inhibitory concentration• MIC is defined as the minimum concentration of antibiotic which will inhibit the growth of the microorganism Hamza
  • Hamza
  • First pass effect/ First pass metabolismThe removal of a drug by the liver, before the drug has become available for use, is called the first pass effect. Hamza
  • EfficacyPower or capacity to produce a desired effectPotencyAmount of drug required to produce a particular responseAffinity:Tendency of a drug to combine with receptor Hamza
  • Therapeutic doseThe dose that may be required to produce a desired effect.Sub Therapeutic doseIndicating a dosage of a drug, less than the amount required for a therapeutic effect. Hamza
  • BacteriostaticAntibiotics that inhibit the growth or reproduction of bacteriaBactericidalAntibiotic that kills the bacteria Hamza
  • Hamza