Berry fruit supplementation and the aging brain 2

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Berry fruit supplementation and the aging brain 2

  1. 1. Berry Fruit Supplementation and the Aging Brain Helin Raudnagel Food Technology EMÜ 2011
  2. 2. Introduction <ul><li>With aging may come several motor and cognitive behavioral defects, such as decreases in balance and coordination and memory deficits </li></ul><ul><li>Occurring to a research carried out at the Tufts University in Boston, these problems can be reduced with combinations of antioxidant/anti-inflammatory polyphenolics found in fruits and vegetables </li></ul><ul><li>These compounds have been recognized to possess many health-promoting benefits </li></ul>
  3. 3. Materials and methods <ul><li>R ats underwent longterm feeding from adulthood (6 months) to middle age (15 months) with a control diet or diets supplemented with vitamin E or with extracts of strawberry or spinach that contained identical antioxidant content to determine if the feeding would prevent age-related decrements in motor and cognitive behavior as well as brain function </li></ul>
  4. 4. Result <ul><li>It has been discovered, that additionally to containing vitamins, fruits and vegetables also contain phytochemical components that contribute substantially to the overall dietary antioxidant intake </li></ul><ul><li>So far, only blueberries, cranberries, Concord grape juice and strawberries have been effective in reversing the motor behavioral deficits. Different studys have shown, that diffenrent fruits (compounds in them) might be acting in different brain regions to produce their beneficial effects </li></ul><ul><li>In addition to antioxidant/anti-inflammatory effects, fruits may also enhance neuronal communication, help out in buffering against excess calcium and reduce stress signals </li></ul>
  5. 5. Result <ul><li>Many findings suggest that the putative properties of flavonoids may prove to be invaluable in altering the neuronal and behavioral effects of aging </li></ul><ul><li>It appears from studies that at least part of the beneficial effects of the berry fruit supplementation may involve enhancements of cell signaling associated with learning and memory </li></ul>
  6. 6. Conclusion <ul><li>It appears that berry fruit, such as blueberries and strawberries, may exert their effects directly through alterations in cell signaling to improve or increase neuronal communication, calcium buffering ability, neuroprotective stress shock proteins, plasticity, and stress signaling pathways </li></ul>
  7. 7. Conclusion <ul><li>N utritional interventions containing polyphenolics, such as berry fruits, may prove to be a valuable asset in strengthening the brain against the ravages of time as they could retard or prevent the development of age-related neurodegenerative diseases </li></ul><ul><li>Early nutritional interventions may even prevent or delay the onset of diseases such as Alzheimer’s disease, because they can reduce oxidative stress and inflammation superimposed upon a stress-vulnerable aging brain </li></ul>
  8. 8. References <ul><li>Journal of agricultural and good chemistry </li></ul><ul><li>http://ddr.nal.usda.gov/bitstream/10113/18349/1/IND44089072.pdf </li></ul>
  9. 9. Thank you for your attention !

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