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Joe Keil

Joe Keil



This power point is from Joe's presentation on October 11, 2013.

This power point is from Joe's presentation on October 11, 2013.



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    Joe Keil Joe Keil Presentation Transcript

    • WELCOME Joe Keil www.whenjustsaynodoesntwork.com 920-323-2354
    • na wi we that do gs ow dru H f or on st r wa have lo 0+ e t4 w as e p e a rs ? th y ION! T VEN PRE
    • day STAT S  NYC consumes 10 tons of illegal drugs each  121 Million Scripts for Hydrocodone in 2012  20% of people who take Benadryl become stimulated  Illegal Drug Business is a 400 billion market  Meth: 2011 MS 2096, TN 1687, ID 1437 and KY 1188
    •  20% of people in US using pills for no reason  More people are using Pills than Cocaine, Heroin, Hallucinogens and Inhalants COMBINED  2010 2.4 million people tried Marijuana for the first time  2010 2.2 million tried pain pills for the first time
    • n: t io es Qu v ia ri T do e s t Wha ean? RX m
    • In 20 01 C han g e in Vi tal Sig n s  Respi ratio ns  Heart rate  Blood pres sure  Body  Big C temp eratu re ha n g adde e: PA d IN w as
    • 6 Ty pe s o f Dru gs  OTC  RX Pr escr  RX Co iption ntrol led  Contr rolle d Ille Drug gal S s treet Desi gner Drug Herb s al  
    • Typ e s of Dr ug Use  Expe a sub rimentat by p stance b ion: Tryin eer p y ch o g ressu ice o re r  Abus get h e: using a dr u igh g  Addic phys ction: Wh body ical harm en the long and you to your er m r l if e atter no s! to
    • EYE EXAM and Drug Influence III-1
    • M-U-R-D-E-R-S, I-N-C, I VI-3A
    • The Eleven Systems of Human Physiology: Murders, Inc. I M is for Muscular System U is for Urinary System R is for Respiratory System D is for Digestive System E is for Endocrine System R is for Reproductive System S is for Skeletal System I is for Integumentary system N is for Nervous System* C is for Circulatory System* I is for Immune System VI-3B
    •  The body has three different Muscular System kinds of muscles  The heart, or cardiac muscle  Smooth muscles, which control the body’s involuntary operations  Striated muscles, which carry out our voluntary movements
    • Urinary System • This system consists of two • kidneys, the bladder, ureters connecting the kidneys to the bladder, and the urethra, which transports the urine out of the body Kidneys filter waste or harmful products, such as drugs and their metabolites, from the blood, and dump these waste products into the bladder. What the Hell is a metabolite?
    • Respiratory System  The major parts of the Respiratory System are the lungs and the diaphragm  The diaphragm is a smooth muscle that draws the air into the lungs and forces it out  Lungs take oxygen and transfer it to the blood, and remove carbon dioxide and some other waste products from the blood, and expel them into the outside air
    • Digestive System  Major components of this system are the tongue, teeth, esophagus, stomach, intestines, liver and pancreas  The Digestive System breaks down large particles of food, until they are of a size and chemical composition that can be absorbed in the blood
    • Endocrine System • The Endocrine System is made up of a number • • of different glands, that secrete hormones Hormones are complex chemicals that travel through the blood stream and that control or regulate certain body processes Some drugs can mimic the effects of hormones, or can react with the hormones in ways that alter the hormones’ effects
    • Reproductive System  The functions of the Reproductive System fall into two roles 1. Self producing (cytogenic) 2. Hormone producing (endocrinic)  We are primarily concerned with hormone production since the hormones produced by the Reproductive System aid the nervous system in its regulatory role
    • Skeletal System  Consists of bones, cartilage and ligaments  The Skeletal System provides support to the body, permits movement, and forms blood cells  It is however, affected by drug abuse, we just may not be able to see it
    • 1981 1982 1985 My Prom Date
    • Integumentary System  Consists of skin, hair, finger and toe nails, and accessory structures  The chief functions of the Integumentary System include protection of the body, control of body temperature, excretion of wastes (i.e. through the sweat) and sensory perception
    • Outside Temperature 14
    • Nervous System  This system consists of the brain, the    brain stem, the spinal cord and the nerves Nerves keep the brain informed of changes in the body’s external and internal environments Nerves also carry messages from the brain to the body’s muscles, tissues and organs The Nervous System controls, coordinates and integrates all physiological process, so the normal body functions can be maintained
    • Circulatory System • • • • • For our purposes, the Circulatory System consists of the heart, the blood vessels (veins and arteries), and the blood Blood carries food, water, oxygen, hormones, antibodies etc. to the tissues and organs Blood also carries heat through the body Blood is the main carrier that brings drugs to the brain The heart pumps and forces the blood to circulate through the body
    • IMMUNE SYSTEM  The immune system protects against disease by destroying “foreign” cells and by inactivating toxins and other foreign chemicals with its antibodies.
    • Homeostasis • The human body is exposed to constantly changing external environment. • Changes are neutralized by the internal environment – the blood • Oxygen, foods, water and other substances are • • constantly leaving body fluids to enter cells, while carbon dioxide and other wastes are leaving the cells to enter these fluids Yet the chemical composition of these fluids remains within very narrow limits This phenomenon is called homeostasis
    • Homeostasis: is the key to drug use: the body is out of balance Dynamic balance or steady state involving levels of salts, water, sugars and other material in the body’s fluids VI-3D
    • Whe n you r sic k  You ta ake m your body eds to pu bala t back nce into Whe n you get h igh i take drug t is d your one s to b to pu to fe ody out t e l hi of ba gh o r fee lance l goo d. 
    • The Male Brain compared to the Female Brain
    • Seriously
    • S er io usly
    • Add in g E T OH to Da te Nigh t
    • Motor Nerves Sensory Nerves Efferent Afferent Voluntary Autonomic Parasympathetic Sympathetic
    • Motor Nerves Sensory Nerves Efferent Afferent Voluntary Autonomic Parasympathetic Sympathetic
    • Fundamental Notions  If something interferes with the messages to the brain sent along the motor nerves, the brain’s control over the heart, the lungs, the muscles and other organs will be distorted  If something interferes with the messages the brain receives from the sensory nerves, the brain’s perception of the outside world and of the body’s status will be distorted  THIS IS HOW DRUGS WORK ON THE FUNCTIONING OF THE NERVOUS SYTEM
    • Motor Nerves • There are two sub-systems of motor nerves: – The voluntary nerves send messages to the striated – muscles that we consciously control The autonomic nerves send messages to the muscles and organs that we do not consciously control, i.e., smooth muscle and cardiac muscle
    • The Autonomic Sub-System • The Autonomic Sub-System divides into two groups: – First, the Sympathetic nerves command the body to react in response to fear, stress, excitement, etc. • “Fight or Flight” Responses: – Blood pressure elevated – Pupils to dilate – Sweat glands to activate – Hair to stand on end – Heart beat to increase and strengthen – Blood vessels of the skin to constrict – Inhibited digestion
    • The Autonomic Sub-System • Second, the Parasympathetic nerves carry messages that produce relaxed and tranquil activities – Pupils to constrict – Heartbeat to slow – Peripheral blood vessels to dilate – Blood pressure to decrease – Digestion to be facilitated
    • Drugs & the Autonomic SubSystems • Some drugs mimic the neurotransmitters that • • travel in the Sympathetic and Parasympathetic nerve systems Drugs that mimic neurotransmitters in the Sympathetic system are called Sympathomimetic drugs. These drugs will artificially create the same effects. Drugs that mimic neurotransmitters in the Parsympathetic system are called Parasympathomimetic drugs. These drugs will artificially create the same effects.
    • A Simplified Concept of a Nerve  The nerves that carry messages to and from the brain often are pictured as “wires” or “telephone wires” that carry electrical signals  A more accurate, but still simplified concept would envision a nerve as a series of broken wire segments, with the segments separated by short spaces, or gaps
    • Simple Concept of a Nerve How does this affect your health?
    • T he abso rbtio elim inati n an d on o f dru gs  Alcoh at ? ol is a fix ed ra te Drug s are ½ liv Wha es t is a h a lf how life a does nd it wo rk?  
    • ½ liv es  Lets s a is 5 h y a drug o ur s s ha l f lif e T ha t simp 5 ho l ur ha y means l f of gone the d every r ug i T he r s efore hour s the the first 5 drug ma j o rity o is go ne o T he r r hal f the e are f of i t. half lives usually a b o ut 8   
    • ADDITIVE EFFECT Effect Effect 1 + 1 = reinforced 1
    • NULL EFFECT No Effect No Effect 0+0=0
    • OVERLAPPING EFFECT No Effect Effect 0+1=1
    • ANTAGONISTIC EFFECT Opposite Effect Effect 1 + -1 = ????