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HVE 2014 Pecha Kucha: Paul de Jonge
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HVE 2014 Pecha Kucha: Paul de Jonge

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Transcript

  • 1. Van koeienpoot tot urologisch product Paul de Jonge, MSc Afdeling urologie, Radboudumc
  • 2. Tissue engineering of weefseltechnologie 2
  • 3. Scaffolds 3
  • 4. Klinische problemen 4
  • 5. Behandelingsstrategieën 5
  • 6. Wereldwijde ontwikkelingen 6
  • 7. Onderzoekslijnen 7
  • 8. Van koeienpoot tot urologisch product COLLAGEN PURIFICATION Cow Achilles tendon PulverizationPurify Freeze drying Purified collagen 0.5 m2 8
  • 9. Van koeienpoot tot urologisch product BIOMATRIX PRODUCTION Purified collagen Freeze dryingBiomatrix Crosslinking Cellen toevoegen Homogenization Bioactive matrix 9
  • 10. Van product naar de patient RA 1 RA 2 RA 3 RA 4 RA5 EMA Clinical trialsMatrices Cell Interaction Animal experiments Clinical Trials Ethics, Patient registry 10
  • 11. Technologie van het Radboudumc 11
  • 12. Productie in cleanroom faciliteiten 12
  • 13. Diermodellen in het CDL 13
  • 14. Blaas model 14
  • 15. Plasbuis model 15
  • 16. Urinederivatie model 16
  • 17. Radboudumc
  • 18. Regionale samenwerking Kennis Kunde Kassa 19
  • 19. Van koeienpoot tot urologisch product Paul de Jonge, MSc Paul.dejonge@radboudumc.nl