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Local hormone
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Local hormone

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local hormone

local hormone

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    Local hormone Local hormone Presentation Transcript

    • LOCAL HORMONE
    • LOCAL HORMONESecreted by body tissue to act locally 1) histamine 2) serotonin 3) prostaglandins 4) erythropoietin 5) gastrointestinal hormones
    • HISTAMINE Hormone that chemically similar to the hormone serotonin Produce by mast cells and basophilsFUNCTIONS: Plays a role in localized immune responses and allergic reaction Increase capillary permeability and vasodilatation Stimulates secretion of gastric juice
    • SEROTONIN Itis a neurotransmitter and primarily found in platelet, brain and intestinal wallFUNCTIONS: Causes intestinal secretion and contraction of smooth muscles Blood clotting
    • PROSTAGLANDIN produced naturally by the body derived from fatty acids, such as arachidonic acid or linoleic acid and they act as mediatorsFUNCTIONS: Inhibit aggregation Regulating blood pressure Blood clotting Uterine contraction during labour Mediating pain and inflammation
    • ERYTHROPOIETIN Synthesized in the kidneysFUNCTIONS: to promote the differentiation and development of red blood cells and to initiate the production of hemoglobin, the molecule within red cells that transports oxygen.
    • GASTROINTESTINAL HORMONE1. Gastrin2. secretin3. Cholecystokinin (CCK)
    • GASTRIN Polypeptidehormone secreted by the mucous lining of the stomachFUNCTION: promote gastric juice secretion
    • SECRETIN it stimulates adenylate cyclase activity and converts ATP to cyclic AMP as it combine with secretin receptor reduces acid secretion from the stomach by inhibiting gastrin release from G cell and helps neutralize the pH of the digestive products entering the duodenum from the stomach
    • CHOLECYSTOKININ mediates a number of physiological processes, including digestion located in the small intestine causes the increased production of hepatic bile stimulates the contraction of the gall bladder and the relaxation of the Sphincter of Oddi