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Hypothalamus
 

Hypothalamus

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hypothalamus

hypothalamus

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    Hypothalamus Hypothalamus Presentation Transcript

    • ENDOCRINE SYSTEM HYPOTHALAMUS
    • HUMAN ENDOCRINE SYSTEM
    • WHAT IS HYPOTHALAMUS?• The portion of the brain that contains a number of small nuclei with a variety of functions.• The control center of all autonomic regulatory activities of the body.
    • LOCATION AND STRUCTURE• It is located in the middle of the base of the brain, and encapsulates the ventral portion of the third ventricle.• A small cone-shaped structure, it projects downward, ending in the pituitary stalk, a tubular connection to the pituitary gland.
    • FUNCTION• The most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland.• It synthesizes and secretes certain neurohormones, often called hypothalamic-releasing hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones.
    • ACTIONPITUITARY GLAND
    • NEUROHORMONES• Thyrotrophin- releasing hormone (TRH)• Corticotrophin-releasing hormone (CRH)• Gonadotropin-releasing hormone (GnRH)• Growth hormone-releasing hormone (GHRH)• Growth hormone-inhibiting hormone• Prolactin-inhibiting hormone• Oxytocin• Vasopressin
    • NEUROHORMONES• Hormone ~ Thyrotrophin-releasing hormone• Other names ~ Prolactin-releasing hormone• Symbol(s)~ TRH/TRF/ or PRH• stimulate thyroid-stimulating hormone (TSH) release from anterior pituitary hormone (primarily).• Stimulate prolactin (PRL) release from anterior pituitary.
    • NEUROHORMONES• Hormone~ Corticotrophin-releasing hormone• Symbols (s) ~ CRH/CRF• Stimulate adrenocorticotrophic hormones (ACTH) release from anterior pituitary.
    • NEUROHORMONES• Hormone~ Gonadotropin-releasing hormone• Symbols (s) ~ GnRH/ LHRH• Stimulating follicle-stimulating hormone (FSH) release from anterior pituitary.• Stimulate luteinizing hormone (LH) release from anterior pituitary.
    • NEUROHORMONES• Hormone~ Growth hormone-releasing hormone.• Symbol (s)~GHRH• Stimulate Growth hormone (GH) release from anterior pituitary.
    • NEUROHORMONES• Hormone~ Somatostatin• Other names~ growth hormone- inhibiting hormone• Symbols (s)~ SS/GHIH• Inhibit the Growth hormone (GH) release from anterior pituitary• Inhibit thyroid-stimulating hormone (TSH) release from anterior pituitary.
    • NEUROHORMONES• Hormone~ Dopamine• Other names~ Prolactin-inhibiting hormone• Symbols (s)~ DA/PIH• Inhibit prolactin release from anterior pituitary.• Responsible for sexual arousal
    • NEUROHORMONES• Hormone~ Oxytocin• For uterine contraction.• Lactation (letdown reflex or milk ejection reflex)
    • NEUROHORMONES• Hormone~ Vasopressin• Other names ~ antidiuretics hormone• Symbols (s)~ ADH/AVP• Increased water permeability in the distal convoluted tubule and collecting duct of nephrons, thus promoting water reabsorption and increasing blood volume