Pa2010 lymphatics


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Pa2010 lymphatics

  1. 1. Glacier National Park
  2. 2. Grimmell Glacier
  3. 3. FUNCTIONS OF THE LYMPHATIC SYSTEM <ul><li>Drainage of tissue fluid and macromolecules back into the circulation. </li></ul><ul><li>Absorption and transport of fat </li></ul><ul><li>Filtration of lymph </li></ul><ul><li>Dissemination of cancer cells </li></ul>
  4. 4. FACTORS INVOLVED IN LYMPH FLOW <ul><li>Smooth muscle in walls of lymph vessels </li></ul><ul><li>2. Compression of vessels due to contraction of surrounding muscles </li></ul><ul><li>3. Negative pressure in thorax generated by respiratory movements </li></ul><ul><li>4. Gravity </li></ul><ul><li>5. Pulsations of arteries </li></ul>
  5. 5. Lymphatic capillaries <ul><li>begin as blind-ended tubes </li></ul><ul><li>converge to form larger lymphatic </li></ul><ul><li>vessels </li></ul>Blood capillary Arteriole Lymph capillary Venule Tissue cell Interstitial fluid Interstitial fluid Endothelium of lymph capillary Anchoring filament Opening
  6. 6. Lymph Capillary Tissue Space (Interstitium) Blood Capillary Arterial End Venous End Water Proteins Oxygen Dust Particles Bacteria 80-90 % of fluid returns to blood stream 1.5-3 L / 24 hrs
  7. 7. Lymph Capillary Tissue Space (Interstitium) Blood Capillary Arterial End Venous End 1.5-3 L / 24 hrs &quot;An adult who weighs 160 pounds has about 5 quarts (4.7 liters) of blood.&quot;
  8. 8. Lymph Capillary Tissue Space (Interstitium) Blood Capillary Arterial End Venous End Fluid component Blood Capillary = Plasma Tissue Space = Interstitial Fluid Lymph Capillary = Lymph
  9. 9. COMPONENTS OF THE LYMPHATIC SYSTEM I. Vessels A. Capillaries 1. Not distributed evenly throughout the body a. Dense meshwork beneath the surfaces of the body b. Sparse in muscle, bone and fascia c. Absent in avascular tissues B. Small lymphatic vessels Contain numerous valves C. Large lymphatic vessels (Trunks or Ducts) Contain numerous valves
  10. 10. <ul><li>Lymph Nodes </li></ul><ul><li>A. Organized accumulation of lymphoid tissue </li></ul><ul><li>B. Scattered along lymphatic vessels </li></ul><ul><li>C. Vary in size </li></ul><ul><li>D. Basic concept of flow of lymph through lymph nodes </li></ul><ul><li>E. Function as filters of lymph </li></ul><ul><li>F. As a general rule, lymph flows through at least one lymph node before it is returned to the circulation </li></ul>
  11. 12. <ul><li>Aggregations of lymphoid tissue </li></ul><ul><li>A. Peyer’s patches ( in small intestines) </li></ul><ul><li>B. Tonsils </li></ul><ul><li>C. Bone marrow </li></ul><ul><li>IV. Lymphoid organs </li></ul><ul><li>A. Spleen </li></ul><ul><li>B. Thymus </li></ul><ul><li>V. Circulating T and B lymphocytes </li></ul>
  12. 13. Inguinal nodes Iliac nodes
  13. 14. Pink Area: Lymph drainage via the right lymphatic duct Gray Area: Lymph drainage via the thoracic duct
  14. 15. Intestinal Trunk Left Lumbar Trunk Thoracic Duct Right Lumbar Trunk
  15. 16. Left Jugular Trunk Left Mediastinal Trunk Thoracic Duct Left Subclavian Trunk
  16. 17. Right Mediastinal Trunk Right Lymphatic Duct Right Jugular Trunk Right Subclavian Trunk
  17. 18. <ul><li>Lymphadenectomy - Removal of a lymph node. </li></ul><ul><li>Lymphadenopathy - Enlarged, sometimes tender, lymph nodes. </li></ul><ul><li>Lymphadenitis - Enlarged, tender, and inflamed lymph nodes resulting from an infection </li></ul><ul><li>Lymphangioma - A benign tumor of the lymphatic vessels. </li></ul><ul><li>Lymphangitis - Inflammation of the lymphatic vessels. </li></ul><ul><li>Lymphedema - accumulation of lymph fluid producing subcutaneous tissue swelling. </li></ul><ul><li>Lymphoma - Any tumor composed of lymphatic tissue </li></ul><ul><li>Lymphostasis - A lymph flow stoppage. </li></ul><ul><li>Splenomegaly - Enlarged spleen </li></ul><ul><li>Elephantiasis - Long-standing edema of one or both lower extremities, and sometimes of the arms or other body parts, that is due to lymphatic obstruction. </li></ul>Medical Terminology Associated with the Lymphatic System
  18. 19. Glacier National Park