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Expert C Kurt Zatloukal 16 Dec 09 Ok
 

Expert C Kurt Zatloukal 16 Dec 09 Ok

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    Expert C Kurt Zatloukal 16 Dec 09 Ok Expert C Kurt Zatloukal 16 Dec 09 Ok Presentation Transcript

    • BBMRI Expert Centres K. Zatloukal Medical University of Graz, Austria Paris, December 16th 2009
    • About BBMRI • BBMRI should provide a pan-European research inrastructure to foster excellence in biomedical research Better projects, faster, cheaper • Access to high quality resources, technologies, services, education and training • Partner for academia and industry SMEs: Strategic partner, customer Pharma: Biomarker and drug development • Incubator for regional development
    • BBMRI Expert Centres A new model of public-private-partnership to improve efficacy of biospecimen research for academia and industry
    • Why Expert Centres? • To generate best possible use of biological samples Specific medical/scientific expertise required for proper sample selection, study design and data interpretation Standardized state of the art analysis platforms prerequisite for data sharing and generation of knowledge High level quality management is prerequisite for industry to trust in data generated in public environment • Alternative to sample shipment Opportunity for research collaborations with countries with export restrictions Improved access to industry (and academia) Avoids impression of sample commercialisation
    • Access by the Industry Surgeons Pathologists Scientific Samples collaboration Med. data Patient Radiologists Patient‘s Sample Industry Oncologists Med. data Cost recovery Lab medicine etc. Problem if no scientific collaboration is possible since financial compensation is no reasonable incentive for contributors and not accepted by public
    • Expert Centers: Model A Samples Samples Med. data Med. data Research data Expertise Expertise Expertise Hospital Expert Industry Biobank Centers Patients Cost recov. Data Expertise Cost recov. In-kind Cost recov. Public-Private Public pre-competitive Private – competitive (not-for-profit) (not-for-profit) (for-profit) Provides efficient access to samples, data and expertise Mutual benefit from expertise and in-kind contributions Joint generation of pre-competitive data and knowledge Reduces requirements for sample shipment Gateway for global collaborations
    • Expert Centers: Model B Samples Samples Med. data Med. data Research data Expertise Expertise Expertise Hospital Expert Industry Biobank Centers Patients Data Data In-kind Cost recov. Cost recov. Cost recov. Public Private – competitive (not-for-profit) (for-profit) Provides efficient access to samples, data and expertise Benefit from in-kind contributions Generation of pre-competitive data and knowledge Reduces requirements for sample shipment Gateway for global collaborations
    • Expert Centers: Model C Samples Samples Processed Med. data Med. data samples Expertise Expertise Expertise Hospital Expert Industry Biobank Centers Patients Cost recov. Cost recov. Cost recov. Public Private – competitive (not-for-profit) (for-profit) Provides efficient access to samples, data and expertise Reduces requirements for raw sample shipment
    • Expert Centers Features • Specifications defined together with industry • Industry participates in QM • Participation in ring trials • Common reference samples • Certification / Accreditation • Confidentialy guaranteed like by CRO • Different models, great flexibility / brand
    • Global Integration of BBMRI by Implementation of the OECD GBRCN Concept in Europe
    • Expert Centres as Highways for Transnational Research Collaborations Biological Biological Resource Samples Resource Centre Samples Medical data Centre Samples Medical Medical Data Data Europe China Research Expert Expert Centre Data Centre
    • Thank you www.bbmri.eu M. Yuille et al. Briefing in Bioinformatics 9: 14-24 (2008)