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BioOhio Update Name or Date An Ohio Thomas Edison Center
<ul><li>hallo  </li></ul><ul><li>bonjour  </li></ul><ul><li>shalom  </li></ul><ul><li>konnichiwa  </li></ul><ul><li>Nihao ...
Ohio More than you know… <ul><li>7th largest state with 11.4 million people </li></ul><ul><li>4 th  in the nation for biot...
The Original Biotechnologies
What is Bioscience? <ul><ul><li>… a broad sector, including: </li></ul></ul><ul><ul><li>Pharmaceuticals </li></ul></ul><ul...
Bioscience Subsectors Agricultural Feedstock & Chemicals <ul><li>Agricultural  processing </li></ul><ul><li>Basic organic ...
Why Listen to me? <ul><li>We want to give you > business, help create regional jobs, give you all > visibility,  > bio lin...
Our History <ul><li>1987 Edison BioTechnology Center (EBTC) </li></ul><ul><li>2001 Moved HQS to Columbus </li></ul><ul><li...
Our History <ul><li>Founded in 1987 as the  Edison BioTechnology Center , BioOhio (formerly  Omeris ) is a non-profit orga...
Be Proud…Be Strategic “ Ohio is one of the best places in the world to optimize the growth of your bioscience company beca...
* Total Ohio bioscience establishments are 1141 (March 1, 2009)
 
Large Ohio Bioscience Companies <ul><li>Procter & Gamble Pharmaceuticals  </li></ul><ul><li>  www.pgpharma.com </li></ul><...
 
3 cities in the top 40 Biotech locations in USA #4 in biotechnology industry strength 2008 All three cities rank higher th...
 
 
 
 
 
 
Direct Commercial Bioscience Economic Impact Summary
Central Ohio Regional Impact
Northeast Ohio Regional Impact
Southwest Ohio Regional Impact
West Central Ohio Regional Impact
Southeast Ohio Regional Impact
Northwest Ohio Regional Impact
 
 
Total Bioscience Funding 2004-2007
 
Top Employers
Top Employers
Top Employers
NAICS
NAICS
Ohio is ranked 8 th  nationally in total patents issued and has more than every country in the world except for Japan, Ger...
Fantastic Hospitals <ul><li>2008 US News and World Report  found 14 top hospitals in Ohio </li></ul><ul><ul><li>Cleveland ...
 
16% of all clinical trials in the US are conducted in Ohio
Distribution of Active Clinical Trials  by Disease As of November 4, 2008
<ul><li>Now 63 Ohio Health Care Venture Funds…More than 100 have invested into Ohio bioscience companies </li></ul><ul><li...
Business Climate Improved <ul><li>Jobs and Progress Plan </li></ul><ul><li>10-year, $5 billion investment in Ohio’s highwa...
Tax Reform
<ul><li>Cardiovascular </li></ul><ul><li>BioPharma </li></ul><ul><li>BioPolymers </li></ul><ul><li>Biomedical Imaging </li...
Ohio Ranks 4 th  in the Nation in Biotech Strength in the latest report
Ohio – National Top 10 AdvaMed
Ohio claims its third Governor's Cup in a row, 06-08, for the most new or expanded capital projects, thanks to the Strickl...
BioOhio’s Balanced Strategy industry growth, resource optimization, community building Company & Capital Formation Company...
BioOhio Strategic Elements   <ul><li>Industry Function: </li></ul><ul><ul><li>Membership </li></ul></ul><ul><ul><li>Fact S...
BioOhio Statewide Board <ul><li>John A Bantle, II ,  PhD, Vice President - Research, Wright State University </li></ul><ul...
By-The Numbers, then & now Year 1991 2001 2008/2009 Number of bio entities in Ohio 170 352 1141  (3.2X) 2009 University R&...
Your Member Organization Your Trade Association / Your Bioscience Chamber <ul><li>Marketing Ohio’s Collaboration & Partner...
Ohio Bioscience Growth Report & Magazines
Company & Capital Formation <ul><ul><li>www.biostart.org </li></ul></ul>www.bioenterprise.com www.techcolumbus.org www.ohi...
What do our Incubators / Accelerators do? <ul><li>Collaborations  with universities, established companies, and start-up c...
Attraction & Expansion <ul><li>Regional Partners – more than 50 </li></ul><ul><ul><li>Monthly phone calls and e-mail updat...
Workforce & Education <ul><li>Community College Partnerships.  Coordinating the efforts of Ohio’s 2 year college’s to prov...
Workforce & Education <ul><li>In Progress & Planned </li></ul><ul><li>Proposals.  </li></ul><ul><ul><li>Will submit BioOhi...
Bioscience Jobs <ul><li>Research & Testing   20,565 companies </li></ul><ul><li>Medical Devices   15,190 companies </li></...
Bioscience Wage Trends <ul><li>The biosciences offer high-paying, quality jobs across a range of occupations </li></ul><ul...
AgBio <ul><li>Ohio is home to the world’s largest soup factory (Campbell’s)  </li></ul><ul><li>Ohio is home to the world’s...
Ohio’s Agricultural Output  $79.6 Billion Ohio’s Chemicals, Plastics, Rubber Materials Output $49 Billion Ohio BioProducts...
Ohio BioProducts Innovation Center   Bio-Polymers and Bio-Product System Solutions Bio-Derived  Feedstocks Monomers and Re...
Impact of the Human Genome Project
Bio-Informatics <ul><li>Genechips (shown) </li></ul><ul><li>Genetic Databases </li></ul><ul><li>Tissue Databases </li></ul...
<ul><li>Carbon Nanotube </li></ul>Nanotechnology / BioMEMS
Human/Computer <ul><li>Implantable Biochips </li></ul><ul><li>Glucose monitoring </li></ul><ul><li>Identification </li></u...
3-D Bioreactor - Mass Production of Embryonic Stem  <ul><li>Problem :  </li></ul><ul><li>Limited ES cell lines and supplie...
Genetically Modified Organisms <ul><li>Opportunity </li></ul><ul><ul><li>Improved pest and disease resistance </li></ul></...
Third Frontier Network (OSCnet) The most advanced IT research network in USA
Technology Innovation Cycle ADVANCED RESEARCH (8-15 years) PRODUCT CYCLE (1-3 years) BREAKTHROUGH (5-8 years) v: Discovery...
Medical Device Commercialization Pathway Concept Development and Initial Research Company Formation / Project Team Secure ...
Typical Product Development Process Source: PTRM
Critical Success Factors <ul><li>Differentiated, superior product/technology  </li></ul><ul><li>Sharp, early product defin...
Sources of Capital <ul><li>Bootstrapping </li></ul><ul><ul><li>Who will benefit from your success?  </li></ul></ul><ul><li...
Pitching <ul><li>10 slides, 20 minutes, 30 Point font </li></ul><ul><li>Differentiate for different audiences </li></ul><u...
Medical Product Development each step has defined Work Processes
Let me know how we can help you! John F. Lewis Jr. Vice President [email_address] 614-675-3686 x7 An Ohio Thomas Edison Ce...
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Bio Ohio Power Point Slide Set 3 10 09

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  • Transcript of "Bio Ohio Power Point Slide Set 3 10 09"

    1. 1. BioOhio Update Name or Date An Ohio Thomas Edison Center
    2. 2. <ul><li>hallo </li></ul><ul><li>bonjour </li></ul><ul><li>shalom </li></ul><ul><li>konnichiwa </li></ul><ul><li>Nihao </li></ul><ul><li>Anyohaseo </li></ul><ul><li>päivää </li></ul><ul><li>Fáilte </li></ul><ul><li>Hola </li></ul>
    3. 3. Ohio More than you know… <ul><li>7th largest state with 11.4 million people </li></ul><ul><li>4 th in the nation for biotech Industry strength </li></ul><ul><li>Within 1 day drive of 61% of USA, 50% Canada </li></ul><ul><li>Highly educated workforce </li></ul><ul><li>> 130 colleges and universities </li></ul>
    4. 4. The Original Biotechnologies
    5. 5. What is Bioscience? <ul><ul><li>… a broad sector, including: </li></ul></ul><ul><ul><li>Pharmaceuticals </li></ul></ul><ul><ul><li>Genomics </li></ul></ul><ul><ul><li>Diagnostics </li></ul></ul><ul><ul><li>Medical devices & equipment </li></ul></ul><ul><ul><li>Bioinformatics </li></ul></ul><ul><ul><li>Biomedical imaging </li></ul></ul><ul><ul><li>Biomaterials </li></ul></ul><ul><ul><li>Clinical Research Organizations </li></ul></ul><ul><ul><li>Environmental </li></ul></ul><ul><ul><li>Regenerative medicine </li></ul></ul><ul><ul><li>Research and development & Testing Labs </li></ul></ul><ul><ul><li>Agricultural bioproducts </li></ul></ul><ul><ul><li>Healthcare Informatics </li></ul></ul><ul><ul><li>Nutraceutical/Food </li></ul></ul>
    6. 6. Bioscience Subsectors Agricultural Feedstock & Chemicals <ul><li>Agricultural processing </li></ul><ul><li>Basic organic chemicals </li></ul><ul><li>Ethyl alcohol mfg. </li></ul><ul><li>Organic fiber mfg. </li></ul><ul><li>Fertilizers </li></ul><ul><li>Pesticides and other agricultural chemicals </li></ul><ul><li>Medicinal & botanicals </li></ul><ul><li>Pharma- ceutical preparations </li></ul><ul><li>Diagnostic substances </li></ul><ul><li>Biological products </li></ul>Drugs & Pharmaceuticals Medical Devices & Equipment <ul><li>Laboratory apparatus & furniture </li></ul><ul><li>Surgical, medical, dental, ophthalmic & analytical instruments & equipment </li></ul><ul><li>Irradiation apparatus & electromedical equipment </li></ul>Hospitals <ul><li>Specialty hospitals </li></ul><ul><li>University medical research hospitals </li></ul><ul><li>Clinical research institutions </li></ul>Research, Testing, & Medical Laboratories <ul><li>Biological research </li></ul><ul><li>Commercial medical research </li></ul><ul><li>Testing laboratories </li></ul><ul><li>Medical laboratories & diagnostic imaging centers </li></ul>Product-Oriented Service -Oriented
    7. 7. Why Listen to me? <ul><li>We want to give you > business, help create regional jobs, give you all > visibility, > bio linkages with rest of the state, more wins </li></ul><ul><ul><li>but we need your help!!! </li></ul></ul><ul><li>Licensed attorney in Ohio 1987 </li></ul><ul><li>18 years international and TBED experience </li></ul><ul><li>Lived in 3 countries, traveled to >50 </li></ul><ul><ul><li>VC in Caribbean, Medical/Pharma/Opto Asia </li></ul></ul><ul><li>Started offices, JV’s in Korea & China, closed one in PRC </li></ul><ul><li>Since 2001 been with BioOhio </li></ul><ul><ul><li>Helped raised more than $1 billion </li></ul></ul>
    8. 8. Our History <ul><li>1987 Edison BioTechnology Center (EBTC) </li></ul><ul><li>2001 Moved HQS to Columbus </li></ul><ul><li>2002 Omeris </li></ul><ul><li>2007 BioOhio </li></ul>
    9. 9. Our History <ul><li>Founded in 1987 as the Edison BioTechnology Center , BioOhio (formerly Omeris ) is a non-profit organization designed to build and accelerate bioscience industry, research, and education in Ohio </li></ul><ul><li>Headquartered in Columbus, with affiliates around the state </li></ul>
    10. 10. Be Proud…Be Strategic “ Ohio is one of the best places in the world to optimize the growth of your bioscience company because we can imbed you in an asset base, 1141 companies and growing; We are a partner that allows you to maximize any or all phases of your business strategy”
    11. 11. * Total Ohio bioscience establishments are 1141 (March 1, 2009)
    12. 13. Large Ohio Bioscience Companies <ul><li>Procter & Gamble Pharmaceuticals </li></ul><ul><li> www.pgpharma.com </li></ul><ul><li>Ethicon Endo-Surgery (J&J) </li></ul><ul><ul><li>www.ethiconendo.com </li></ul></ul><ul><li>Cardinal Health </li></ul><ul><ul><li>www.Cardinal.com </li></ul></ul><ul><li>Battelle Memorial Institute </li></ul><ul><li> www.battelle.org </li></ul><ul><li>STERIS </li></ul><ul><ul><li>www.steris.com </li></ul></ul><ul><li>Philips Medical Systems </li></ul><ul><ul><li>www.medical.philips.com </li></ul></ul><ul><li>Abbott Nutrition (Ross Laboratories) </li></ul><ul><li> http://abbottnutrition.com/ </li></ul><ul><li>Chemical Abstracts </li></ul><ul><ul><li>www.cas.org </li></ul></ul><ul><li>Mettler-Toledo </li></ul><ul><ul><li>www.mt.com </li></ul></ul><ul><li>Invacare </li></ul><ul><ul><li>www.invacare.com </li></ul></ul>… and lots of emerging and mid sized companies
    13. 15. 3 cities in the top 40 Biotech locations in USA #4 in biotechnology industry strength 2008 All three cities rank higher than the 100 city average in Research grant awards in Bio- Sciences $630 Million in NIH Awards in 2008! State City Rank OH Cleveland-Akron 20 Columbus 22 Cincinnati 28
    14. 22. Direct Commercial Bioscience Economic Impact Summary
    15. 23. Central Ohio Regional Impact
    16. 24. Northeast Ohio Regional Impact
    17. 25. Southwest Ohio Regional Impact
    18. 26. West Central Ohio Regional Impact
    19. 27. Southeast Ohio Regional Impact
    20. 28. Northwest Ohio Regional Impact
    21. 31. Total Bioscience Funding 2004-2007
    22. 33. Top Employers
    23. 34. Top Employers
    24. 35. Top Employers
    25. 36. NAICS
    26. 37. NAICS
    27. 38. Ohio is ranked 8 th nationally in total patents issued and has more than every country in the world except for Japan, Germany, and the UK
    28. 39. Fantastic Hospitals <ul><li>2008 US News and World Report found 14 top hospitals in Ohio </li></ul><ul><ul><li>Cleveland Clinic 4 th best hospital in the nation and Top Heart Center in the country for 14 straight years </li></ul></ul><ul><ul><li>Rainbow Babies Children’s Hospital (Cleveland) 2 nd in neonatal care </li></ul></ul><ul><ul><li>4 pediatric hospitals ranked in the Top 15 </li></ul></ul><ul><ul><li>6 of the top 50 Endocrinology Centers, most in the nation </li></ul></ul><ul><ul><li>6 top 50 Orthopedic centers </li></ul></ul><ul><ul><li>3 top 50 adult cancer centers, </li></ul></ul><ul><li>Child Magazine ranked Nationwide Children’s Hospital (Columbus) as the #1 facility for pediatric emergency care in 2007 </li></ul><ul><li>Thomson Reuters National Top 100, which measures hospital reliability, ranked 14 Ohio hospitals, tied for most in the nation in 2007 </li></ul><ul><ul><li>Most ranked facilities in the nation over the last four years </li></ul></ul>
    29. 41. 16% of all clinical trials in the US are conducted in Ohio
    30. 42. Distribution of Active Clinical Trials by Disease As of November 4, 2008
    31. 43. <ul><li>Now 63 Ohio Health Care Venture Funds…More than 100 have invested into Ohio bioscience companies </li></ul><ul><li>Adena Ventures </li></ul><ul><li>Akron ArchAngels Network </li></ul><ul><li>Alpha Capital Partners </li></ul><ul><li>Arboretum Ventures </li></ul><ul><li>Athenian Ventures </li></ul><ul><li>Battelle Ventures </li></ul><ul><li>Blue Chip Venture Company </li></ul><ul><li>Blue Point Capital </li></ul><ul><li>Bridge Investment Fund </li></ul><ul><li>Case Technology Ventures </li></ul><ul><li>Charter Life Sciences </li></ul><ul><li>Chrysalis Ventures </li></ul><ul><li>CID Equity Partners </li></ul><ul><li>Cincinnati Children's Tomorrow Fund </li></ul><ul><li>CincyTech Ventures </li></ul><ul><li>Cleveland Clinic Innovations </li></ul><ul><li>Core Network </li></ul><ul><li>Draper Triangle Ventures </li></ul><ul><li>Early Stage Partners </li></ul><ul><li>Edgewater Capital </li></ul><ul><li>Entrepreneurs “E” Fund </li></ul><ul><li>Everett Partners </li></ul><ul><li>Fletecher Spaght </li></ul><ul><li>Fort Washington Capital </li></ul><ul><li>Foundation Medical Partners </li></ul><ul><li>Frantz Medical Ventures </li></ul><ul><li>Glengary Ventures </li></ul><ul><li>GLIDE Fund </li></ul><ul><li>iNetwork BioOpportunity </li></ul><ul><li>Innovation Fund of LCCC </li></ul><ul><li>Isabella Capital </li></ul><ul><li>JumpStart </li></ul><ul><li>Kadima Partners </li></ul><ul><li>Miami Valley Ventures </li></ul><ul><li>Morgenthaler Ventures </li></ul><ul><li>Mutual Capital </li></ul><ul><li>NCIC Capital </li></ul><ul><li>NCT Ventures </li></ul><ul><li>North Coast Angels </li></ul><ul><li>Oakwood Medical </li></ul><ul><li>Ohio Tech Angels I, II & III </li></ul><ul><li>Primus Capital </li></ul><ul><li>Queen City Angels </li></ul><ul><li>Radius Ventures </li></ul><ul><li>Redwood Holdings </li></ul><ul><li>Reservoir Ventures </li></ul><ul><li>River Cities Capital Funds </li></ul><ul><li>Riverside Capital </li></ul><ul><li>Rivervest Ventures </li></ul><ul><li>Scius (Spire Capital) </li></ul><ul><li>Soin International </li></ul><ul><li>RMS Investments </li></ul><ul><li>Rocket Ventures </li></ul><ul><li>Southern Ohio Creates Capital </li></ul><ul><li>Summit Health Ventures </li></ul><ul><li>Sycamore Partners </li></ul><ul><li>Talisman Capital </li></ul><ul><li>TechColumbus TechGenesis </li></ul><ul><li>TechColumbus RCF </li></ul><ul><li>Teton Capital </li></ul><ul><li>Triathlon Medical Ventures </li></ul>
    32. 44. Business Climate Improved <ul><li>Jobs and Progress Plan </li></ul><ul><li>10-year, $5 billion investment in Ohio’s highways </li></ul><ul><li>Tax Reform </li></ul><ul><ul><li>21 percent income tax reduction </li></ul></ul><ul><ul><li>Eliminating property taxes on investments in machinery and equipment </li></ul></ul><ul><ul><li>No business tax on products exported out of Ohio </li></ul></ul><ul><ul><li>First $1 million of gross receipts tax-free </li></ul></ul><ul><li>Lawsuit Reform </li></ul><ul><li>Third Frontier $1.6 billion </li></ul><ul><li>Ohio’s Bipartisan Jobs Stimulus Plan $1.57 billion </li></ul><ul><ul><li>($100 million, $50 million, $250 million) </li></ul></ul>
    33. 45. Tax Reform
    34. 46. <ul><li>Cardiovascular </li></ul><ul><li>BioPharma </li></ul><ul><li>BioPolymers </li></ul><ul><li>Biomedical Imaging </li></ul><ul><li>AgBio </li></ul>
    35. 47. Ohio Ranks 4 th in the Nation in Biotech Strength in the latest report
    36. 48. Ohio – National Top 10 AdvaMed
    37. 49. Ohio claims its third Governor's Cup in a row, 06-08, for the most new or expanded capital projects, thanks to the Strickland Administration's focus on taking steps necessary to be competitive, even in a challenging economic environment.
    38. 50. BioOhio’s Balanced Strategy industry growth, resource optimization, community building Company & Capital Formation Company Attraction & Expansion Member / Trade Association Industry Function Bioscience Workforce & Education
    39. 51. BioOhio Strategic Elements <ul><li>Industry Function: </li></ul><ul><ul><li>Membership </li></ul></ul><ul><ul><li>Fact Sourcing </li></ul></ul><ul><ul><li>Networking </li></ul></ul><ul><ul><li>Branding </li></ul></ul><ul><ul><li>Advocacy </li></ul></ul><ul><li>Asset-based Company Attraction & Expansion </li></ul><ul><li>Workforce & Education </li></ul><ul><li>Company & Capital Formation </li></ul>
    40. 52. BioOhio Statewide Board <ul><li>John A Bantle, II , PhD, Vice President - Research, Wright State University </li></ul><ul><li>Timothy G. Biro , CEO - MORK Process; Partner, Ohio Innovation Fund & Reservoir Ventures </li></ul><ul><li>Greg Blackmore, Sr. Vice President and Group President, Life Sciences - STERIS </li></ul><ul><li>Rathindra Bose, PhD, Vice President for Research & Creative Activity - Ohio University </li></ul><ul><li>Mark A. Collar , Chairman - Third Frontier Advisory Board </li></ul><ul><li>Mark J. Coticchia, VP Research and Technology Management - Case Western Reserve </li></ul><ul><li>Sandra J. Degen , PhD, Vice President for Research - University of Cincinnati </li></ul><ul><li>Anthony J. Dennis, PhD, President & CEO - BioOhio </li></ul><ul><li>Paul DiCorletto, Chairman - Lerner Research Institute (Cleveland Clinic) </li></ul><ul><li>Kevin Driscoll, PhD , Exec Director, Global Health Care Connect & Develop-Procter & Gamble </li></ul><ul><li>John Fisher, Executive Vice President - Ohio Farm Bureau Federation </li></ul><ul><li>Mike Hooven , President & CEO - Enable Medical Technologies </li></ul><ul><li>Peter G. Kleinhenz , General Partner - CID Equity Partners </li></ul><ul><li>Barbara Kunz, President - Health & Life Science Global Division Battelle </li></ul><ul><li>Thomas J. Murphy, President & COO - Ben Venue Laboratories </li></ul><ul><li>John M. Rice , PhD, Managing Partner - Triathlon Medical Ventures </li></ul><ul><li>David R. Scholl , PhD, President & CEO - Diagnostic Hybrids </li></ul><ul><li>James A. Scozzie , PhD, Senior Vice President - BioEnterprise </li></ul><ul><li>Arnold W. Strauss, MD, Director - Cincinnati Children’s Research Foundation </li></ul><ul><li>Caroline Whitacre, PhD, Senior Vice President for Research - The Ohio State University </li></ul>
    41. 53. By-The Numbers, then & now Year 1991 2001 2008/2009 Number of bio entities in Ohio 170 352 1141 (3.2X) 2009 University R&D expenditures $285 million $481 million $1.1 billion (2.3X) New Company starts ≈ 12 12 65 per year (5.4X) 2004-08 Private capital raised for new starts Unknown $14 million $189 million (13.5X) $473 million IPO/Acquisitions 2008 Bioscience Capital sources (in State) 4 8 63 (7.9) 2009 BioOhio (EBTC) membership 52 86 280 (3.3X) 2009
    42. 54. Your Member Organization Your Trade Association / Your Bioscience Chamber <ul><li>Marketing Ohio’s Collaboration & Partnership Opportunities </li></ul><ul><ul><ul><li>New Website launched July 2008 </li></ul></ul></ul><ul><ul><ul><li>Trade Missions (Japan, Taiwan, China, USA, Germany, Israel) </li></ul></ul></ul><ul><ul><ul><li>Various Publications </li></ul></ul></ul><ul><ul><ul><li>LinkedIn </li></ul></ul></ul><ul><ul><ul><li>News Ticker, Webinars, Newsletters and much more </li></ul></ul></ul><ul><li>Networking </li></ul><ul><ul><ul><li>BioOhio </li></ul></ul></ul><ul><ul><ul><li>BIO Mid America Venture Forum </li></ul></ul></ul><ul><ul><ul><li>PhRMA events </li></ul></ul></ul><ul><ul><ul><li>AdvaMed events </li></ul></ul></ul><ul><ul><ul><li>AgBio events </li></ul></ul></ul><ul><ul><ul><li>National BIO events </li></ul></ul></ul><ul><ul><ul><li>Regional Affiliate events </li></ul></ul></ul><ul><li>Advocacy ( National & Ohio) </li></ul><ul><ul><ul><li>SBIR Legislation, Patent Reform </li></ul></ul></ul><ul><ul><ul><li>Drug Pricing and importation </li></ul></ul></ul><ul><ul><ul><li>Stem cell research / Human Cloning </li></ul></ul></ul><ul><ul><ul><li>Bioscience workforce training </li></ul></ul></ul><ul><ul><ul><li>Third Frontier funding strategies </li></ul></ul></ul>
    43. 55. Ohio Bioscience Growth Report & Magazines
    44. 56. Company & Capital Formation <ul><ul><li>www.biostart.org </li></ul></ul>www.bioenterprise.com www.techcolumbus.org www.ohiou.edu/biotech www.rgp.org www.ci.akron.oh.us
    45. 57. What do our Incubators / Accelerators do? <ul><li>Collaborations with universities, established companies, and start-up companies; national and international collaborations </li></ul><ul><li>Business development to help established and startup companies make contacts and pursue success </li></ul><ul><li>Management support for startup companies, “portable executives,” “entrepreneurs in residence” until the company operates on its own </li></ul><ul><li>Professional Services referrals to attorneys, accountants, regulatory expertise and others who understand the technology, the startup company environment, international business </li></ul><ul><li>Access to Capital helping startups find investors, and helping investors find companies to invest in </li></ul>
    46. 58. Attraction & Expansion <ul><li>Regional Partners – more than 50 </li></ul><ul><ul><li>Monthly phone calls and e-mail updates </li></ul></ul><ul><li>Program Operations </li></ul><ul><ul><li>Finished an attraction brochure </li></ul></ul><ul><ul><li>Workforce/Talent recruitment remains #1 issue </li></ul></ul><ul><li>Global Cardiovascular Innovation Center (GCIC) </li></ul><ul><ul><li>Relationship and Partnership growing and functioning well </li></ul></ul><ul><ul><li>Supply Chain directory </li></ul></ul><ul><li>Expansions </li></ul><ul><ul><li>Site Selection Magazine “Governor’s Cup” 3 years in a row </li></ul></ul><ul><ul><li>Area Development Magazine Silver Shovel Award </li></ul></ul><ul><ul><li>119 Bioscience expansions or new facilities 05-07 </li></ul></ul><ul><li>OEDA/TeamOhio relationship </li></ul><ul><li>Israel, Taiwan, Finland, Ireland, Hungary, China, Germany </li></ul>
    47. 59. Workforce & Education <ul><li>Community College Partnerships. Coordinating the efforts of Ohio’s 2 year college’s to provide comprehensive programs in support of bioscience industry expansion, e.g. introduction of manufacturing content </li></ul><ul><li>Proposals Submitted. Submitted NSF & DOL proposals seeking additional funding in support of biomanufacturing industry expansion </li></ul><ul><li>Blue Ribbon Panel. Invited participant on national 50 member NSF panel to set standards for education bio-technicians. Report published August 2008; www.aacc.nche.edu/ateprogram </li></ul><ul><li>Career Fairs. Held 3 rd annual Ohio Bioscience Career Fair in November 2008, and rolling out regional events during 2009 </li></ul><ul><li>Job awareness & Community Outreach. Entered into partnership with the Society for Manufacturing Engineers Educational Foundation to address improving bio-manufacturing image </li></ul>
    48. 60. Workforce & Education <ul><li>In Progress & Planned </li></ul><ul><li>Proposals. </li></ul><ul><ul><li>Will submit BioOhio led NSF-ATE proposal, and partner in Lakeland CC led NSF-ATE proposal focused on outreach and awareness in northeast Ohio. </li></ul></ul><ul><ul><li>Engage consulting group to secure additional federal funds </li></ul></ul><ul><ul><li>Continue to push proposal to develop a comprehensive workforce strategy for Bio in Ohio </li></ul></ul><ul><li>Job Awareness & Community Outreach . Work with SME Educational Foundation and others (Indianapolis WIB, MichBio) to implement a comprehensive plan for Ohio/Indiana/Michigan then expand to midwest, and possibly nationally </li></ul><ul><li>Career Fairs. Hold annual Ohio Bioscience Career Fair, and support/initiate others. Lakeland CC will hold NE Ohio bioscience career fair November 5, sponsored by BioOhio. </li></ul><ul><li>Community College Partnerships. Continue to enhance and roll out bioscience workforce support program in partnership with OBOR </li></ul><ul><li>Strategy. Continue working with State (OBOR, ODOD, ODE) to develop comprehensive biosciences “Industry Sector” workforce strategy </li></ul>
    49. 61. Bioscience Jobs <ul><li>Research & Testing 20,565 companies </li></ul><ul><li>Medical Devices 15,190 companies </li></ul><ul><li>Drugs & Pharmaceuticals 2,589 companies </li></ul><ul><li>Ag Feedstock & Chemicals 2,111 companies </li></ul>Distribution of Bioscience Employment by Subsector Source: Battelle calculations based on Bureau of Labor Statistics, QCEW program data from the Minnesota Implan Group. Data include Puerto Rico. Agricultural Feedstock & Chemicals Drugs & Pharmaceuticals Medical Devices & Equipment Research, Testing, & Medical Laboratories
    50. 62. Bioscience Wage Trends <ul><li>The biosciences offer high-paying, quality jobs across a range of occupations </li></ul><ul><li>Bioscience workers earn $26,772 more than the average U.S. private sector wage, with all four subsectors above the national average </li></ul><ul><li>Since 2001, real (inflation-adjusted) earnings are up 6.4% for bioscience workers, compared to just a 1.4% increase for private sector </li></ul>
    51. 63. AgBio <ul><li>Ohio is home to the world’s largest soup factory (Campbell’s) </li></ul><ul><li>Ohio is home to the world’s largest ketchup factory (Heinz) </li></ul><ul><li>Ohio is home to the world’s largest pizza plant (Pillsbury) </li></ul><ul><li>Ohio is home to the world’s largest yogurt plant (Dannon) </li></ul><ul><li>Ohio is home to the country’s largest fructose plant (Cargill) </li></ul><ul><li>More Swiss cheese is produced in Ohio than in Wisconsin </li></ul><ul><li>Center for Innovative Food Technology </li></ul><ul><li>935 food processing facilities 935 </li></ul><ul><li>Ohio Agricultural Research & Development Center </li></ul>
    52. 64. Ohio’s Agricultural Output $79.6 Billion Ohio’s Chemicals, Plastics, Rubber Materials Output $49 Billion Ohio BioProducts Innovation Center                        
    53. 65. Ohio BioProducts Innovation Center Bio-Polymers and Bio-Product System Solutions Bio-Derived Feedstocks Monomers and Resins <ul><li>Soybean Oils </li></ul><ul><li>Next Gen Soybean Oils </li></ul><ul><li>Soy Proteins </li></ul><ul><li>Corn based carbohydrates/sugars </li></ul><ul><li>Polyacids </li></ul><ul><li>Polyols </li></ul><ul><li>Monomers </li></ul><ul><li>Oligomers and Resins </li></ul><ul><li>Specialty Compounds </li></ul><ul><li>Coatings, Binders, Toners </li></ul><ul><li>Adhesives and Sealants </li></ul><ul><li>Composites </li></ul><ul><li>Solvents, Plasticizers </li></ul><ul><li>Lubricants </li></ul><ul><li>Surfactants, Cleaners </li></ul><ul><li>Fertilizer Systems </li></ul>
    54. 66. Impact of the Human Genome Project
    55. 67. Bio-Informatics <ul><li>Genechips (shown) </li></ul><ul><li>Genetic Databases </li></ul><ul><li>Tissue Databases </li></ul><ul><li>www.osc.edu </li></ul><ul><li>www.daytaohio.com </li></ul>
    56. 68. <ul><li>Carbon Nanotube </li></ul>Nanotechnology / BioMEMS
    57. 69. Human/Computer <ul><li>Implantable Biochips </li></ul><ul><li>Glucose monitoring </li></ul><ul><li>Identification </li></ul><ul><li>Retinal implant (shown) </li></ul>
    58. 70. 3-D Bioreactor - Mass Production of Embryonic Stem <ul><li>Problem : </li></ul><ul><li>Limited ES cell lines and supplies for regenerative medicine and other biomedical applications </li></ul><ul><li>Solution : in vitro expansion </li></ul><ul><li>2-D Cell culture: labor intensive (frequent sub culturing) and expensive (growth factors; surface coating) </li></ul><ul><li>Need : Better and cheaper 3-D culturing method in bioreactor with controlled environment </li></ul>
    59. 71. Genetically Modified Organisms <ul><li>Opportunity </li></ul><ul><ul><li>Improved pest and disease resistance </li></ul></ul><ul><ul><li>Better economics </li></ul></ul><ul><ul><li>Less use of chemicals Challenge </li></ul></ul><ul><li>Challenges </li></ul><ul><ul><li>Fear of the unknown </li></ul></ul><ul><ul><li>Misunderstanding </li></ul></ul><ul><ul><li>Scientists not attending to social issues </li></ul></ul>
    60. 72. Third Frontier Network (OSCnet) The most advanced IT research network in USA
    61. 73. Technology Innovation Cycle ADVANCED RESEARCH (8-15 years) PRODUCT CYCLE (1-3 years) BREAKTHROUGH (5-8 years) v: Discovery Development Application Product Development Involves the “Application” of Technology t e r C r o s s I n d u s t r y S o u r c e s F e d e r a l R e s e a r c h C o l l a b o r a t i v e R e s e a r c h R e s e a r c h U n i v e r s i t i e s G l o b a l S o u r c i n g C o r p o r a t e L a b s I n t e r n a t i o n a l S o u r c e s I n t e g r a t i o n S e n s e & L o c a t e G a p A s s e s s m e n t A s s e s s P r o d u c t P l a t f o r m P r o d u c C u s t o m D r i v e s U n m e t N e e d s Develop
    62. 74. Medical Device Commercialization Pathway Concept Development and Initial Research Company Formation / Project Team Secure IP Portfolio Product Engineering and Prototype Development Pre-Clinical and Clinical Studies Manufacturing Development/ expansion for clinical trials Clinical Trials/Outcomes FDA Approval and Market Launch Expansion/ Investment in Working Capital $ A B
    63. 75. Typical Product Development Process Source: PTRM
    64. 76. Critical Success Factors <ul><li>Differentiated, superior product/technology </li></ul><ul><li>Sharp, early product definition </li></ul><ul><li>Quality of pre-development activities </li></ul><ul><li>Strong market orientation </li></ul><ul><li>Reduced cost / drives revenue </li></ul><ul><li>Customers willing to pay $ </li></ul><ul><li>Effective organizational structure </li></ul><ul><li>Engaged Partners </li></ul><ul><li>Quality of execution </li></ul><ul><ul><li>Technical, Business </li></ul></ul>
    65. 77. Sources of Capital <ul><li>Bootstrapping </li></ul><ul><ul><li>Who will benefit from your success? </li></ul></ul><ul><li>FF&F </li></ul><ul><ul><li>Find enthusiastic supporters in your personal network </li></ul></ul><ul><ul><li>Put your own money in (investors want to see this commitment) </li></ul></ul><ul><li>Angels </li></ul><ul><ul><li>Looking to make money, but also hope to get involved and add value </li></ul></ul><ul><li>Grants </li></ul><ul><ul><li>Lots of free and cheap money out there </li></ul></ul><ul><li>Venture / Private Equity </li></ul><ul><ul><li>Care about making a return on investment </li></ul></ul><ul><ul><li>Often do not have time or ambition to get to involved </li></ul></ul><ul><li>SBA / Banks </li></ul><ul><ul><li>Always take debt before equity, but often difficult as they require security (receivables, assets…) </li></ul></ul>
    66. 78. Pitching <ul><li>10 slides, 20 minutes, 30 Point font </li></ul><ul><li>Differentiate for different audiences </li></ul><ul><li>Investor </li></ul><ul><li>Sales Prospect </li></ul><ul><li>Partner Prospect </li></ul><ul><li>B to B </li></ul><ul><li>Problem </li></ul><ul><li>Solution </li></ul><ul><li>Business Model </li></ul><ul><li>Your Magic </li></ul><ul><li>Mktg/Sales </li></ul><ul><li>Competition </li></ul><ul><li>Mgmt Team </li></ul><ul><li>Financial Projections </li></ul><ul><li>Current Status – The Ask </li></ul>
    67. 79. Medical Product Development each step has defined Work Processes
    68. 80. Let me know how we can help you! John F. Lewis Jr. Vice President [email_address] 614-675-3686 x7 An Ohio Thomas Edison Center
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