Calcitriol Metabolism Resource

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Calcitriol Metabolism Resource

  1. 1. Calcitriol Biosynthesis and metabolism • Vitamin D is not strictly a vitamin, it can be synthesized in the skin, and under most conditions that is the major source of the vitamin. • Only when sunlight exposure is inadequate is a dietary source required. • Its main function is in the regulation of calcium absorption and homeostasis
  2. 2. Calcitriol Biosynthesis and metabolism • Most of its actions are mediated by way of nuclear receptors that regulate gene expression. • Deficiency, leading to rickets in children and osteomalacia in adults.

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