2.22.2010 organelles

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2.22.2010 organelles

  1. 1. 2.22.2010 – Organelles<br /><ul><li>Slide 1
  2. 2. Cells create organelles where the proteins/enzymes are concentrated in particular areas in the cell.
  3. 3. Endomembrane System
  4. 4. Endoplasmic Reticulum
  5. 5. Golgi
  6. 6. Transport Vesicles
  7. 7. Endosomes
  8. 8. Lysosomes
  9. 9. Continuous w/ nuclear envelope, specifically ER
  10. 10. Transport vesicles to the plasma membrane
  11. 11. Isolated Organelles
  12. 12. Nucleus
  13. 13. Mitochondria
  14. 14. Peroxisomes
  15. 15. Debated issue if part of isolated or endomembrane system
  16. 16. Can bud off from ER like a similar organelle, lysosomes
  17. 17. Can bud off from ER so can be isolated or part of endomembrane sys.
  18. 18. Can regenerate themselves
  19. 19. Endoplasmic Reticulum
  20. 20. Smooth ER
  21. 21. Buds and sends vesicles to golgi
  22. 22. Cis
  23. 23. Medial
  24. 24. Trans regions of golgi
  25. 25. Trans golgi to plasma membrane is the direction of budding
  26. 26. Synthesis of lipids, cholesterol, steroids
  27. 27. Calcium storage site
  28. 28. Ca2+ must be kept at low concentrations because it’s a signaling molecule.
  29. 29. Detoxifying alcohol/drugs
  30. 30. Hydroxylation, where –OH groups are placed on to alcohol and drug molecules to make them more soluble so they can be removed easier
  31. 31. Catalyzed by cytochrome P-450
  32. 32. Upregulated when high levels of alcohol or drugs
  33. 33. Alcoholics have cronically high levels of cytochrome P-450
  34. 34. Breakdown of glycogen to glucose
  35. 35. Storage molecules can be broken down and used for glycolysis (example)
  36. 36. Rough ER
  37. 37. Contains ribosome on its membrane
  38. 38. Synthesizes proteins
  39. 39. Modification of proteins
  40. 40. Glycosylation of proteins
  41. 41. Carb groups are placed onto proteins to glycosylate
  42. 42. N-glycosylation
  43. 43. Cisternae
  44. 44. The name ER tells you that it’s a network within the cytoplasm continuous with nuclear envelope.

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