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genegames.org/cure/

        B. Good
Group meeting Sep. 14, 2012
today
• First week of /cure/
  – What happened?
• Next steps
  – Changes for next deployment
Website
• 347 distinct site visitors
   – 62% US, 29% China
• 38% of visits > 2 minutes
• 4.7% of visits > 30 minutes
• analytics
Players
• 125 registered, 108 played mammal,
• 58 finished a board on cancer challenge.
                            of the 58 players

   Have Cancer       Consider               Most recent degree
   Knowledge         themselves a
                     Biologist
   no 41%            no 53%                 BS 29%
   NA 1              NA 1                   MA 17%
   yes 55%           yes 45%                NA 3%, other 3%
                                            PhD 47%

                 similar proportions if include the
                 ones that stopped at mammal
Registrations
 36 registrations on
 our Sunday, mostly
 China                                     created
             9/14/12


             9/13/12


             9/12/12


             9/11/12


             9/10/12
                                                                             created

              9/9/12


              9/8/12


              9/7/12
Launch day
              9/6/12
                       0   20    40   60        80   100        120    140


                                                           Accumulating registrations
Hands played
               350

stolo
               300


dreamtwister   250
ryanM
               200
kiefer89
               150


               100



    Hands       50


                 0
                     0   10   20        30   40   50   60


                               Player
Time spent
  RyanM 23 hours
  Shenyije
  Stolo
                   90000
                   80000
                   70000
                   60000
                   50000
Total seconds      40000                                             Series1
between cards      30000

played within      20000

one board          10000
                       0
                           0      10    20      30    40   50   60



                                             Player

                               About 61 hours spent in total.
                               This is a lower bound.
ryanM
Community progress
10+ players defeat board
So is it working?
• Baseline for random gene selection within our
  2500 genes.
  – Random samples of 10 genes, n = 1000
  – cross-validation performance
  – min: 47.46922024623803
  – max: 67.44186046511628
  –mean: 55.12311901504788
  – std dev: 4.140814369975244
  – median: 54.651162790697676
Gene ranking take 1
• For each board
  – find the first hand played by each (unfiltered)
    player
     • for all of those hands (min 5 diff players)
     • calculate the frequency of selection F for each gene.


• Sort genes according decreasing F
Ehh, sort of maybe
• Frequency-based selection, all players, top 10
  ranked genes
  – CV = 60
• Frequency-based selection, all players that
  declare knowledge of cancer and have played
  < 13 cards per hand on average, top 10 ranked
  genes
  – CV = 63
Next steps
• Open – how to stop people from optimizing
  hands based on cv performance yet still give
  them feedback on what is generally working?
• How to make it more fun?
• How to collect more useful data?

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Short update on The Cure game first week

  • 1. genegames.org/cure/ B. Good Group meeting Sep. 14, 2012
  • 2. today • First week of /cure/ – What happened? • Next steps – Changes for next deployment
  • 3. Website • 347 distinct site visitors – 62% US, 29% China • 38% of visits > 2 minutes • 4.7% of visits > 30 minutes • analytics
  • 4. Players • 125 registered, 108 played mammal, • 58 finished a board on cancer challenge. of the 58 players Have Cancer Consider Most recent degree Knowledge themselves a Biologist no 41% no 53% BS 29% NA 1 NA 1 MA 17% yes 55% yes 45% NA 3%, other 3% PhD 47% similar proportions if include the ones that stopped at mammal
  • 5. Registrations 36 registrations on our Sunday, mostly China created 9/14/12 9/13/12 9/12/12 9/11/12 9/10/12 created 9/9/12 9/8/12 9/7/12 Launch day 9/6/12 0 20 40 60 80 100 120 140 Accumulating registrations
  • 6. Hands played 350 stolo 300 dreamtwister 250 ryanM 200 kiefer89 150 100 Hands 50 0 0 10 20 30 40 50 60 Player
  • 7. Time spent RyanM 23 hours Shenyije Stolo 90000 80000 70000 60000 50000 Total seconds 40000 Series1 between cards 30000 played within 20000 one board 10000 0 0 10 20 30 40 50 60 Player About 61 hours spent in total. This is a lower bound.
  • 10. So is it working? • Baseline for random gene selection within our 2500 genes. – Random samples of 10 genes, n = 1000 – cross-validation performance – min: 47.46922024623803 – max: 67.44186046511628 –mean: 55.12311901504788 – std dev: 4.140814369975244 – median: 54.651162790697676
  • 11. Gene ranking take 1 • For each board – find the first hand played by each (unfiltered) player • for all of those hands (min 5 diff players) • calculate the frequency of selection F for each gene. • Sort genes according decreasing F
  • 12. Ehh, sort of maybe • Frequency-based selection, all players, top 10 ranked genes – CV = 60 • Frequency-based selection, all players that declare knowledge of cancer and have played < 13 cards per hand on average, top 10 ranked genes – CV = 63
  • 13. Next steps • Open – how to stop people from optimizing hands based on cv performance yet still give them feedback on what is generally working? • How to make it more fun? • How to collect more useful data?

Editor's Notes

  1. for 25 genes mean is 56. otherwise almost exactly the same