Sir chris odonnel

S ir C h r is R etired C hief E xecutive, Smith & N ephew O ’ D o n n e llF u t u r e M e d ic a l T e c h n o lo g ie s a n d D r iv e r s

F E S T IV A L S H E F F I E L D 2 0 12 Medical Technology Innovative high-value added manufacturing technologySir Christopher O’DonnellMarch 2012

1970’s 1990’s• High speed clinical chemistry analyser •Hydrocellular wound dressings• Servo-control infant incubator • Lightweight fracture casting products• Portable human isolation nursing system • High vapour permeable IV dressings • ‘Easy to use’ orthopaedic implant instruments Medical Technology Innovation – Personal History1980’s 2000’s• Infection control urinary catheter • Tissue engineered wound dressings• Integrated heart by-pass oxygenator • Oxidised zirconium hips/knees& tube packs • Bio-resorbable arthroscopic fixation Sir Christopher O’Donnell – Sheffield 2012

Healthcare system demands innovationM a r k e t d y n a m ic s V a lu e a d d e d in n o v a t io n s• Demographics• Active lifestyle • Smarter materials• Better-informed patients • Less invasive (MIS) procedures• Declining surgeon income • Accelerated healing• Nurse shortage • Alternative therapies• Healthcare Spending • Faster patient turn-round• Specialization • Positive health economics• New technologies • Ease/convenience of use Sir Christopher O’Donnell – Sheffield 2012

Global Medical Technology Market by Region 2011 Global Market Value: $250bnSource: Espciom 2011 Sir Christopher O’Donnell – Sheffield 2012

to innovate / differentiate products 1. D i f f e r e n c e s i n c u s t o m e r d e m a n d :- • Levels of healthcare spend per capita • Approval, procurement and reimbursement practicesSource: Arthur D Little/ DTI report 2004 Sir Christopher O’Donnell – Sheffield 2012

Factors affecting national ability to innovate / differentiate products Ø A c c e s s t o s c i e n t i f i c /c l i n i c a l k n o w le d g e : - • Varies according to maturity of technology Increasing Technology Maturity • Clinicians have multiple linkages with innovation Embryonic Growth Mature Ageing process IV Diagnostics reagents Orthopaedics Market Size Active wound First“product” management Imaging breakthrough Advanced wound Elec.med/respiratory Radiotherapy management (Tissue engineering) TimeSource: Arthur D Little/ DTI report 2004 Sir Christopher O’Donnell – Sheffield 2012

MedTech Innovation• Medical technology is a large and growing global industry• Innovation is the key driver of growth and is global in nature• Technology plays a major role in driving this innovation – but needs strong industry / clinician / health service collaboration to succeed Sir Christopher O’Donnell – Sheffield 2012

MedTech Sector in the UK UK Yorkshire Region Companies - 150Companies - 2,500+ Turnover - £1.8bnDomestic Market - £6bn Strengths - WoundcareExports - £5bn+ Orthopaedic Devices Surgical InstrumentsEmployees - 50,000 Sir Christopher O’Donnell – Sheffield 2012

Example of Innovation: Knee Joint Replacement SMITH & NEPHEW GENESIS II Knee Systemwith Oxinium™ Technology Sir Christopher O’Donnell – Sheffield 2012

OXINIUM™ – a major innovation in reducing wear • Ceramic is generally accepted as the ideal bearing surface for total joints but has strength limitations• For more than 15 years Smith & Nephew worked to develop an innovative material that combines the benefits of ceramic with the strength of metal• The result OXINIUM™, a metal with an integral ceramic surface• Performing clinically equivalent to or better than conventional alternative Cobalt Chrome• In the Laboratory OXINIUM™ wear at 30 years is less than Cobalt Chrome at 3 years Sir Christopher O’Donnell – Sheffield 2012

Manufacturing Process DevelopmentProcess IssuesDefine & Prove Alloy Biocompatibility Scale Up and Small scale novel alloyProve Smelting Net Shape No other Manufacturer Forging forges Zirconium Shaping & Zirconium dust combusts Grinding Process spontaneously and burns at 3,000°C Finishing & Completely novel mirror Polishing Processes finish requirements Sir Christopher O’Donnell – Sheffield 2012

innovationM a r k e t d y n a m ic s O X IN IU M• Demographics • Smarter materials• Active lifestyle • Less invasive (MIS) procedures• Better-informed patients • Accelerated healing• Declining surgeon income • Alternative therapies• Nurse shortage • Faster patient turn-round• Healthcare Spending • Positive health economics• Specialization • Ease/convenience of use• New technologies Sir Christopher O’Donnell – Sheffield 2012

More Information?• INDUSTRY OVERVIEW Strengths and Opportunity: Annual Update Dec 2011 HMG; www.bis.gov.uk• LOCAL INDUSTRY NETWORK/ASSISTANCE Medilink Yorkshire & Humber Ltd www.medilink.co.uk Telephone: 01142 329200• INNOVATION IN THE HEALTH SERVICE Devices for Dignity (D4D) Healthcare Technology Co-Operative Sheffield Teaching Hospital www.devicesfordignity.org.uk Sir Christopher O’Donnell – Sheffield 2012

F E S T IV A L S H E F F I E L D 2 0 12 Medical Technology Innovative high-value added manufacturing technologySir Christopher O’DonnellMarch 2012

Sir chris odonnel

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