SOLO review 2011 part 1

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SOLO review 2011 part 1

  1. 1. 0.0 <ul><li>Case order is randomized </li></ul><ul><li>A blank page precedes every diagnosis </li></ul><ul><li>Every diagnosis is verbatim from answer key </li></ul><ul><li>Case numbers </li></ul><ul><ul><li>1-15: July 2010 </li></ul></ul><ul><ul><li>16-30: August 2010 </li></ul></ul><ul><ul><li>31-50: September 2010 </li></ul></ul><ul><ul><li>51-72: November 2010 </li></ul></ul><ul><ul><li>73-87: February 2011 </li></ul></ul><ul><ul><li>88-97: April 2011 </li></ul></ul><ul><ul><li>98-113: May 2011 </li></ul></ul>
  2. 2. 16.0 57F, hysterectomy for uterine prolapse Case 1
  3. 3. 16.1 Case 1
  4. 4. 16.2 Case 1
  5. 5. 16.3 Case 1
  6. 6. 16.4
  7. 7. 16.5 <ul><li>Cervical atrophy </li></ul>
  8. 8. 22.0 Case 7 32F, LGSIL on Pap, HPV DNA+ by history. Biopsy from cervix.
  9. 9. 22.1 Case 7
  10. 10. 22.2 Case 7
  11. 11. 22.3
  12. 12. 22.4 <ul><li>Unremarkable ectocervix </li></ul>
  13. 13. 83.0 Case 11 49M: Retroperitoneal/mesenteric mass
  14. 14. 83.1 Case 11
  15. 15. 83.2 Case 11
  16. 16. 83.3 Case 11
  17. 17. 83.4 Case 11
  18. 18. 83.5 Case 11
  19. 19. 83.6 Case 11
  20. 20. 83.7 <ul><li>Diagnosis </li></ul><ul><li>Name the stain </li></ul>
  21. 21. 83.8 <ul><li>Case 11 . </li></ul><ul><li>2 Diagnosis: Fibromatosis </li></ul><ul><li>1 Name the stain: B-catenin </li></ul>
  22. 22. 12.0 Case 12 FNA palpable breast mass
  23. 23. 12.1 Case 12
  24. 24. 12.2 Case 12
  25. 25. 12.3
  26. 26. 12.4 <ul><li>Fibroadenoma </li></ul>
  27. 27. 105.0 Bilateral ovarian masses Case 8
  28. 28. 105.1 Case 8
  29. 29. 105.2 Case 8
  30. 30. 105.3 Case 8
  31. 31. 105.4 Case 8
  32. 32. 105.5
  33. 33. 105.6 <ul><li>Serous borderline tumor, typical </li></ul>
  34. 34. 60.0 61F: Once again, a mass in front of the ear Case 10
  35. 35. 60.1 Case 10
  36. 36. 60.2 Case 10
  37. 37. 60.3 Case 10
  38. 38. 60.4 Case 10
  39. 39. 60.5 Case 10
  40. 40. 60.6
  41. 41. 60.7 <ul><li>Myoepithelial carcinoma dd clear cell carcinoma, RCC, HCC but you would have to discuss and exclude (immunos for former, vascularity for latter) </li></ul>
  42. 42. 78.0 Case 6 An invasive mammary carcinoma
  43. 43. 78.1 Case 6
  44. 44. 78.2 Case 6
  45. 45. 78.3 <ul><li>a. Name the stain </li></ul>
  46. 46. 78.4 <ul><li>Case 6 . An immunostain performed on an invasive breast carcinoma. </li></ul><ul><li>2 a. Name the stain: Her-2 </li></ul>
  47. 47. 26.0 46F Endometrial biopsy Case 11
  48. 48. 26.1 Case 11
  49. 49. 26.2 Case 11
  50. 50. 26.3 Case 11
  51. 51. 26.4 Case 11
  52. 52. 26.5 Case 11
  53. 53. 26.6
  54. 54. 26.7 <ul><li>Extreme exogenous hormonal influence (progesterone) </li></ul>
  55. 55. 24.0 Case 9 23 F, cervical biopsy
  56. 56. 24.1 Case 9
  57. 57. 24.2 Case 9
  58. 58. 24.3
  59. 59. 24.4 <ul><li>HGSIL/CIN II </li></ul>
  60. 60. 57.0 6M: Enlarged retro-auricular lymph node Case 7
  61. 61. 57.1 Case 7
  62. 62. 57.2 Case 7
  63. 63. 57.3 Case 7
  64. 64. 57.4 Case 7
  65. 65. 57.5
  66. 66. 57.6 <ul><li>Langerhan cell histriocytosis </li></ul>
  67. 67. 18.0 55F complains of vulvar irritation Vulva biopsy Case 3
  68. 68. 18.1 Case 3
  69. 69. 18.2 Case 3
  70. 70. 18.3 Case 3
  71. 71. 18.4
  72. 72. 18.5 <ul><li>VIN3 with microinvasion </li></ul>
  73. 73. 113.0 46F Each ovary measures approximately 4 x 3 x 3 cm. Cut surface is white and bosselated. Case 15
  74. 74. 113.1 Case 15
  75. 75. 113.2 Case 15
  76. 76. 113.3 Case 15
  77. 77. 113.4 Case 15
  78. 78. 113.5
  79. 79. 113.6 <ul><li>Metastatic lobular carcinoma </li></ul>
  80. 80. 77.0 Case 5 No history
  81. 81. 77.1 Case 5
  82. 82. 77.2 Case 5
  83. 83. 77.3 Case 5
  84. 84. 77.4 Case 5
  85. 85. 77.5 Case 5
  86. 86. 77.6 <ul><li>a. Name the stain </li></ul><ul><li>b. What is the diagnosis? </li></ul>
  87. 87. 77.7 <ul><li>Case 5 . </li></ul><ul><li>1 a. Name the stain: S-100 </li></ul><ul><li>2 b. What is the diagnosis? Benign lymph node; no melanoma </li></ul>
  88. 88. 85.0 Case 13 66M: Elevated PSA
  89. 89. 85.1 Case 13
  90. 90. 85.2 Case 13
  91. 91. 85.3 Case 13
  92. 92. 85.4 Case 13
  93. 93. 85.5 Case 13
  94. 94. 85.6 Case 13
  95. 95. 85.7 <ul><li>a. Most comprehensive diagnosis on sections provided </li></ul><ul><li>b. Name the stain </li></ul>
  96. 96. 85.8 <ul><li>Case 13 . </li></ul><ul><li>2 a. Most comprehensive diagnosis on sections provided: </li></ul><ul><li>Ductal adenocarcinoma Gleason 4+4 score 8. Perineural invasion is present </li></ul><ul><li>1 b. Name the stain: P63 </li></ul>
  97. 97. 63.0 62F: Increasing abdominal girth Case 13
  98. 98. 63.1 Case 13
  99. 99. 63.2 Case 13
  100. 100. 63.3 Case 13
  101. 101. 63.4 Case 13
  102. 102. 63.5 Case 13
  103. 103. 63.6 Case 13
  104. 104. 63.7
  105. 105. 63.8 <ul><li>Mucinous adenocarcinoma adherent/metastatic to spleen depending on whether you think that it is in the organ or not </li></ul>
  106. 106. 99.0 Bilateral cystic ovarian masses Case 2
  107. 107. 99.1 Case 2
  108. 108. 99.2 Case 2
  109. 109. 99.3 Case 2
  110. 110. 99.4 Case 2
  111. 111. 99.5 Case 2
  112. 112. 99.6 Case 2
  113. 113. 99.7 Case 2
  114. 114. 99.8
  115. 115. 99.9 <ul><li>Serous papillary cystadenofibroma </li></ul>
  116. 116. 50.0 Case 20 45M: Dysphagia
  117. 117. 50.1 Case 20
  118. 118. 50.2 Case 20
  119. 119. 50.3 Case 20
  120. 120. 50.4 Case 20
  121. 121. 50.5
  122. 122. 50.6 <ul><li>Herpses esophagitis </li></ul>
  123. 123. 112.0 43F Left ovarian mass 16 x 14 x 11 cm, 1139 gms Solid and cystic cut surface Case 14
  124. 124. 112.1 Case 14
  125. 125. 112.2 Case 14
  126. 126. 112.3 Case 14
  127. 127. 112.4 Case 14
  128. 128. 112.5 Case 14
  129. 129. 112.6 Case 14
  130. 130. 112.7 Case 14
  131. 131. 112.8 Case 14
  132. 132. 112.9
  133. 133. 112.10 <ul><li>Clear cell carcinoma </li></ul>
  134. 134. 30.0 28F: Tissue designated as endometrial polyp Case 15
  135. 135. 30.1 Case 15
  136. 136. 30.2 Case 15
  137. 137. 30.3 Case 15
  138. 138. 30.4 Case 15
  139. 139. 30.5 Case 15
  140. 140. 30.6 Case 15
  141. 141. 30.7
  142. 142. 30.8 <ul><li>Proliferative endometrium </li></ul>
  143. 143. 94.0 Case 7 64F
  144. 144. 94.1 Case 7
  145. 145. 94.2 Case 7
  146. 146. 94.3 Case 7
  147. 147. 94.4 Case 7
  148. 148. 94.5 Case 7
  149. 149. 94.6
  150. 150. 94.7
  151. 151. 45.0 Case 15 20M: Rectal biopsy
  152. 152. 45.1 Case 15
  153. 153. 45.2 Case 15
  154. 154. 45.3 Case 15
  155. 155. 45.4
  156. 156. 45.5 <ul><li>Non-nec granulomas AFB, GMS, r/o Crohn’s </li></ul>
  157. 157. 109.0 Cystic ovarian mass Case 12
  158. 158. 109.1 Case 12
  159. 159. 109.2 Case 12
  160. 160. 109.3 Case 12
  161. 161. 109.4
  162. 162. 109.5 <ul><li>Serous borderline tumor micropapillary </li></ul>
  163. 163. 2.0 Case 2 28F: Right breast mass
  164. 164. 2.1 Case 2
  165. 165. 2.2 Case 2
  166. 166. 2.3 Case 2
  167. 167. 2.4 Case 2
  168. 168. 2.5 Case 2
  169. 169. 2.6
  170. 170. 2.7 <ul><li>Lactational change </li></ul>
  171. 171. 80.0 Case 8 49M: Resection for metastases.
  172. 172. 80.1 Case 8
  173. 173. 80.2 Case 8
  174. 174. 80.3 Case 8
  175. 175. 80.4 Case 8
  176. 176. 80.5 <ul><li>a. Name the organ </li></ul><ul><li>b. What is/are the most likely primary site(s ) ? </li></ul><ul><li>c. This immunostain supports the phenotype of the metastasis. Name the stain </li></ul>
  177. 177. 80.6 <ul><li>Case 8 . </li></ul><ul><li>1 a. Name the organ: Liver </li></ul><ul><li>2 b. What is/are the most likely primary site(s ) ? </li></ul><ul><li>Esophagus, lung, head and neck </li></ul><ul><li>1 c. This immunostain supports the phenotype of the metastasis. </li></ul><ul><li>Name the stain: P63 </li></ul>
  178. 178. 72.0 Diarrhea Case 22
  179. 179. 72.1 Case 22
  180. 180. 72.2 Case 22
  181. 181. 72.3 Case 22
  182. 182. 72.4
  183. 183. 72.5 <ul><li>cryptosporidiosis </li></ul>
  184. 184. 79.0 Case 7 62M: History of treated acute myeloid leukemia. Testicular mass
  185. 185. 79.1 Case 7
  186. 186. 79.2 Case 7
  187. 187. 79.3 Case 7 b
  188. 188. 79.4 Case 7 c
  189. 189. 79.5 <ul><li>a. What is the diagnosis? </li></ul><ul><li>b. Name the stain </li></ul><ul><li>c. Name the stain </li></ul>
  190. 190. 79.6 <ul><li>Case 7 . </li></ul><ul><li>2 a. What is the diagnosis? Seminoma </li></ul><ul><li>1 b. Name the stain: Oct3/4 </li></ul><ul><li>1 c. Name the stain: PLAP/C-Kit </li></ul>
  191. 191. 38.0 Case 8 32F: No history provided
  192. 192. 38.1 Case 8
  193. 193. 38.2 Case 8
  194. 194. 38.3 Case 8
  195. 195. 38.4 Case 8
  196. 196. 38.5
  197. 197. 38.6 <ul><li>SIL (P16, MIB1) to CIN II/HGSIL </li></ul>
  198. 198. 73.0 Case 1 No history
  199. 199. 73.1 Case 1
  200. 200. 73.2 Case 1
  201. 201. 73.3 Case 1 a
  202. 202. 73.4 Case 1 b
  203. 203. 73.5 <ul><li>Case 1 . A section of breast tissue. Name the stains. </li></ul>
  204. 204. 73.6 <ul><li>1 a. ER/PR </li></ul><ul><li>1 b. SMA/Smooth muscle heavy chain myosin/Caldesmon </li></ul>
  205. 205. 101.0 Middle aged woman Enormously enlarged unilateral multiloculated ovarian mass Smooth lining, viscous contents Case 4
  206. 206. 101.1 Case 4
  207. 207. 101.2 Case 4
  208. 208. 101.3 Case 4
  209. 209. 101.4 Case 4
  210. 210. 101.5 Case 4
  211. 211. 101.6
  212. 212. 101.7 <ul><li>Mucinous cystadenoma </li></ul>
  213. 213. 110.0 62 F Two masses in the ovary. The first is homogenous, white and firm It measures 2.5 x 1 x 1 cm Case 13a
  214. 214. 110.1 Case 13a
  215. 215. 110.2 Case 13a
  216. 216. 110.3 Case 13a
  217. 217. 110.4 Case 13a
  218. 218. 110.5 Case 13a
  219. 219. 110.6
  220. 220. 110.7 <ul><li>Fibroma </li></ul>
  221. 221. 111.0 The other mass is cystic with a smooth lining and an intramural nodule. The cyst lining is smooth I made that up because somebody did not comment on the lining Case 13b
  222. 222. 111.1 Case 13b
  223. 223. 111.2 Case 13b
  224. 224. 111.3 Case 13b
  225. 225. 111.4 Case 13b
  226. 226. 111.5 Case 13b
  227. 227. 111.6 Case 13b
  228. 228. 111.7
  229. 229. 111.8 <ul><li>Brenner tumor </li></ul>
  230. 230. 43.0 Case 13 Calcifications in breast
  231. 231. 43.1 Case 13 0.2 cm
  232. 232. 43.2 Case 13
  233. 233. 43.3 Case 13
  234. 234. 43.4 Case 13
  235. 235. 43.5 Case 13
  236. 236. 43.6 Case 13
  237. 237. 43.7
  238. 238. 43.8 <ul><li>ADH from columnar lesion; Ca++ </li></ul>
  239. 239. 103.0 32F Unilateral enlarged ovary Approximately 7.0 cm Cystic and solid Case 6
  240. 240. 103.1 Case 6
  241. 241. 103.2 Case 6
  242. 242. 103.3 Case 6
  243. 243. 103.4 Case 6
  244. 244. 103.5 Case 6
  245. 245. 103.6
  246. 246. 103.7 <ul><li>Sertoli Leydig cell tumor </li></ul>
  247. 247. 74.0 Case 2 49F: Breast biopsy for calcifications.
  248. 248. 74.1 Case 2
  249. 249. 74.2 Case 2
  250. 250. 74.3 Case 2
  251. 251. 74.4 Case 2
  252. 252. 74.5 Case 2
  253. 253. 74.6 Case 2
  254. 254. 74.7 <ul><li>a. Name the stai n </li></ul><ul><li>b. Most comprehensive diagnosis on sections provided: </li></ul>
  255. 255. 74.8 <ul><li>Case 2 . </li></ul><ul><li>1 a. Name the stai n: E-cadherin </li></ul><ul><li>2 b. Most comprehensive diagnosis on sections provided: </li></ul><ul><li>Low grade DCIS </li></ul><ul><li>LCIS with comedo necrosis </li></ul><ul><li>Calcifications present in LCIS </li></ul>
  256. 256. 5.0 Case 5 History of DCIS in this breast
  257. 257. 5.1 Case 5
  258. 258. 5.2 Case 5
  259. 259. 5.3 Case 5
  260. 260. 5.4 Case 5
  261. 261. 5.5 Case 5
  262. 262. 5.6 Case 5
  263. 263. 5.7
  264. 264. 5.8 <ul><li>Radial scar, calcifications present </li></ul>
  265. 265. 14.0 Case 14 No history
  266. 266. 14.1 Case 14
  267. 267. 14.2 Case 14
  268. 268. 14.3 Case 14
  269. 269. 14.4 Case 14
  270. 270. 14.5 Case 14
  271. 271. 14.6 Case 14
  272. 272. 14.7
  273. 273. 14.8 <ul><li>Well diff neuroendocrine tumor </li></ul>
  274. 274. 9.0 Case 9 Mastectomy specimen
  275. 275. 9.1 Case 9
  276. 276. 9.2 Case 9
  277. 277. 9.3 Case 9
  278. 278. 9.4 Case 9
  279. 279. 9.5 Case 9
  280. 280. 9.6
  281. 281. 9.7 <ul><li>Peripheral papillomas </li></ul>
  282. 282. 90.0 Case 3 43F: Tumor, right wrist
  283. 283. 90.1 Case 3
  284. 284. 90.2 Case 3
  285. 285. 90.3 Case 3
  286. 286. 90.4 Case 3
  287. 287. 90.5 Case 3
  288. 288. 90.6
  289. 289. 90.7
  290. 290. 75.0 Case 3 55M: Tonsillar mass
  291. 291. 75.1 Case 3
  292. 292. 75.2 Case 3
  293. 293. 75.3 Case 3
  294. 294. 75.4 Case 3
  295. 295. 75.5 <ul><li>a. Most comprehensive diagnosis on sections provided </li></ul><ul><li>b. Name the stain </li></ul>
  296. 296. 75.6 <ul><li>Case 3 . </li></ul><ul><li>2 a. Most comprehensive diagnosis on sections provided: </li></ul><ul><li>Basaloid squamous cell carcinoma </li></ul><ul><li>2 b. Name the stain: P16 </li></ul>

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