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SOLO review 2011 part 1
SOLO review 2011 part 1
SOLO review 2011 part 1
SOLO review 2011 part 1
SOLO review 2011 part 1
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SOLO review 2011 part 1

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  • 1. 0.0 <ul><li>Case order is randomized </li></ul><ul><li>A blank page precedes every diagnosis </li></ul><ul><li>Every diagnosis is verbatim from answer key </li></ul><ul><li>Case numbers </li></ul><ul><ul><li>1-15: July 2010 </li></ul></ul><ul><ul><li>16-30: August 2010 </li></ul></ul><ul><ul><li>31-50: September 2010 </li></ul></ul><ul><ul><li>51-72: November 2010 </li></ul></ul><ul><ul><li>73-87: February 2011 </li></ul></ul><ul><ul><li>88-97: April 2011 </li></ul></ul><ul><ul><li>98-113: May 2011 </li></ul></ul>
  • 2. 16.0 57F, hysterectomy for uterine prolapse Case 1
  • 3. 16.1 Case 1
  • 4. 16.2 Case 1
  • 5. 16.3 Case 1
  • 6. 16.4
  • 7. 16.5 <ul><li>Cervical atrophy </li></ul>
  • 8. 22.0 Case 7 32F, LGSIL on Pap, HPV DNA+ by history. Biopsy from cervix.
  • 9. 22.1 Case 7
  • 10. 22.2 Case 7
  • 11. 22.3
  • 12. 22.4 <ul><li>Unremarkable ectocervix </li></ul>
  • 13. 83.0 Case 11 49M: Retroperitoneal/mesenteric mass
  • 14. 83.1 Case 11
  • 15. 83.2 Case 11
  • 16. 83.3 Case 11
  • 17. 83.4 Case 11
  • 18. 83.5 Case 11
  • 19. 83.6 Case 11
  • 20. 83.7 <ul><li>Diagnosis </li></ul><ul><li>Name the stain </li></ul>
  • 21. 83.8 <ul><li>Case 11 . </li></ul><ul><li>2 Diagnosis: Fibromatosis </li></ul><ul><li>1 Name the stain: B-catenin </li></ul>
  • 22. 12.0 Case 12 FNA palpable breast mass
  • 23. 12.1 Case 12
  • 24. 12.2 Case 12
  • 25. 12.3
  • 26. 12.4 <ul><li>Fibroadenoma </li></ul>
  • 27. 105.0 Bilateral ovarian masses Case 8
  • 28. 105.1 Case 8
  • 29. 105.2 Case 8
  • 30. 105.3 Case 8
  • 31. 105.4 Case 8
  • 32. 105.5
  • 33. 105.6 <ul><li>Serous borderline tumor, typical </li></ul>
  • 34. 60.0 61F: Once again, a mass in front of the ear Case 10
  • 35. 60.1 Case 10
  • 36. 60.2 Case 10
  • 37. 60.3 Case 10
  • 38. 60.4 Case 10
  • 39. 60.5 Case 10
  • 40. 60.6
  • 41. 60.7 <ul><li>Myoepithelial carcinoma dd clear cell carcinoma, RCC, HCC but you would have to discuss and exclude (immunos for former, vascularity for latter) </li></ul>
  • 42. 78.0 Case 6 An invasive mammary carcinoma
  • 43. 78.1 Case 6
  • 44. 78.2 Case 6
  • 45. 78.3 <ul><li>a. Name the stain </li></ul>
  • 46. 78.4 <ul><li>Case 6 . An immunostain performed on an invasive breast carcinoma. </li></ul><ul><li>2 a. Name the stain: Her-2 </li></ul>
  • 47. 26.0 46F Endometrial biopsy Case 11
  • 48. 26.1 Case 11
  • 49. 26.2 Case 11
  • 50. 26.3 Case 11
  • 51. 26.4 Case 11
  • 52. 26.5 Case 11
  • 53. 26.6
  • 54. 26.7 <ul><li>Extreme exogenous hormonal influence (progesterone) </li></ul>
  • 55. 24.0 Case 9 23 F, cervical biopsy
  • 56. 24.1 Case 9
  • 57. 24.2 Case 9
  • 58. 24.3
  • 59. 24.4 <ul><li>HGSIL/CIN II </li></ul>
  • 60. 57.0 6M: Enlarged retro-auricular lymph node Case 7
  • 61. 57.1 Case 7
  • 62. 57.2 Case 7
  • 63. 57.3 Case 7
  • 64. 57.4 Case 7
  • 65. 57.5
  • 66. 57.6 <ul><li>Langerhan cell histriocytosis </li></ul>
  • 67. 18.0 55F complains of vulvar irritation Vulva biopsy Case 3
  • 68. 18.1 Case 3
  • 69. 18.2 Case 3
  • 70. 18.3 Case 3
  • 71. 18.4
  • 72. 18.5 <ul><li>VIN3 with microinvasion </li></ul>
  • 73. 113.0 46F Each ovary measures approximately 4 x 3 x 3 cm. Cut surface is white and bosselated. Case 15
  • 74. 113.1 Case 15
  • 75. 113.2 Case 15
  • 76. 113.3 Case 15
  • 77. 113.4 Case 15
  • 78. 113.5
  • 79. 113.6 <ul><li>Metastatic lobular carcinoma </li></ul>
  • 80. 77.0 Case 5 No history
  • 81. 77.1 Case 5
  • 82. 77.2 Case 5
  • 83. 77.3 Case 5
  • 84. 77.4 Case 5
  • 85. 77.5 Case 5
  • 86. 77.6 <ul><li>a. Name the stain </li></ul><ul><li>b. What is the diagnosis? </li></ul>
  • 87. 77.7 <ul><li>Case 5 . </li></ul><ul><li>1 a. Name the stain: S-100 </li></ul><ul><li>2 b. What is the diagnosis? Benign lymph node; no melanoma </li></ul>
  • 88. 85.0 Case 13 66M: Elevated PSA
  • 89. 85.1 Case 13
  • 90. 85.2 Case 13
  • 91. 85.3 Case 13
  • 92. 85.4 Case 13
  • 93. 85.5 Case 13
  • 94. 85.6 Case 13
  • 95. 85.7 <ul><li>a. Most comprehensive diagnosis on sections provided </li></ul><ul><li>b. Name the stain </li></ul>
  • 96. 85.8 <ul><li>Case 13 . </li></ul><ul><li>2 a. Most comprehensive diagnosis on sections provided: </li></ul><ul><li>Ductal adenocarcinoma Gleason 4+4 score 8. Perineural invasion is present </li></ul><ul><li>1 b. Name the stain: P63 </li></ul>
  • 97. 63.0 62F: Increasing abdominal girth Case 13
  • 98. 63.1 Case 13
  • 99. 63.2 Case 13
  • 100. 63.3 Case 13
  • 101. 63.4 Case 13
  • 102. 63.5 Case 13
  • 103. 63.6 Case 13
  • 104. 63.7
  • 105. 63.8 <ul><li>Mucinous adenocarcinoma adherent/metastatic to spleen depending on whether you think that it is in the organ or not </li></ul>
  • 106. 99.0 Bilateral cystic ovarian masses Case 2
  • 107. 99.1 Case 2
  • 108. 99.2 Case 2
  • 109. 99.3 Case 2
  • 110. 99.4 Case 2
  • 111. 99.5 Case 2
  • 112. 99.6 Case 2
  • 113. 99.7 Case 2
  • 114. 99.8
  • 115. 99.9 <ul><li>Serous papillary cystadenofibroma </li></ul>
  • 116. 50.0 Case 20 45M: Dysphagia
  • 117. 50.1 Case 20
  • 118. 50.2 Case 20
  • 119. 50.3 Case 20
  • 120. 50.4 Case 20
  • 121. 50.5
  • 122. 50.6 <ul><li>Herpses esophagitis </li></ul>
  • 123. 112.0 43F Left ovarian mass 16 x 14 x 11 cm, 1139 gms Solid and cystic cut surface Case 14
  • 124. 112.1 Case 14
  • 125. 112.2 Case 14
  • 126. 112.3 Case 14
  • 127. 112.4 Case 14
  • 128. 112.5 Case 14
  • 129. 112.6 Case 14
  • 130. 112.7 Case 14
  • 131. 112.8 Case 14
  • 132. 112.9
  • 133. 112.10 <ul><li>Clear cell carcinoma </li></ul>
  • 134. 30.0 28F: Tissue designated as endometrial polyp Case 15
  • 135. 30.1 Case 15
  • 136. 30.2 Case 15
  • 137. 30.3 Case 15
  • 138. 30.4 Case 15
  • 139. 30.5 Case 15
  • 140. 30.6 Case 15
  • 141. 30.7
  • 142. 30.8 <ul><li>Proliferative endometrium </li></ul>
  • 143. 94.0 Case 7 64F
  • 144. 94.1 Case 7
  • 145. 94.2 Case 7
  • 146. 94.3 Case 7
  • 147. 94.4 Case 7
  • 148. 94.5 Case 7
  • 149. 94.6
  • 150. 94.7
  • 151. 45.0 Case 15 20M: Rectal biopsy
  • 152. 45.1 Case 15
  • 153. 45.2 Case 15
  • 154. 45.3 Case 15
  • 155. 45.4
  • 156. 45.5 <ul><li>Non-nec granulomas AFB, GMS, r/o Crohn’s </li></ul>
  • 157. 109.0 Cystic ovarian mass Case 12
  • 158. 109.1 Case 12
  • 159. 109.2 Case 12
  • 160. 109.3 Case 12
  • 161. 109.4
  • 162. 109.5 <ul><li>Serous borderline tumor micropapillary </li></ul>
  • 163. 2.0 Case 2 28F: Right breast mass
  • 164. 2.1 Case 2
  • 165. 2.2 Case 2
  • 166. 2.3 Case 2
  • 167. 2.4 Case 2
  • 168. 2.5 Case 2
  • 169. 2.6
  • 170. 2.7 <ul><li>Lactational change </li></ul>
  • 171. 80.0 Case 8 49M: Resection for metastases.
  • 172. 80.1 Case 8
  • 173. 80.2 Case 8
  • 174. 80.3 Case 8
  • 175. 80.4 Case 8
  • 176. 80.5 <ul><li>a. Name the organ </li></ul><ul><li>b. What is/are the most likely primary site(s ) ? </li></ul><ul><li>c. This immunostain supports the phenotype of the metastasis. Name the stain </li></ul>
  • 177. 80.6 <ul><li>Case 8 . </li></ul><ul><li>1 a. Name the organ: Liver </li></ul><ul><li>2 b. What is/are the most likely primary site(s ) ? </li></ul><ul><li>Esophagus, lung, head and neck </li></ul><ul><li>1 c. This immunostain supports the phenotype of the metastasis. </li></ul><ul><li>Name the stain: P63 </li></ul>
  • 178. 72.0 Diarrhea Case 22
  • 179. 72.1 Case 22
  • 180. 72.2 Case 22
  • 181. 72.3 Case 22
  • 182. 72.4
  • 183. 72.5 <ul><li>cryptosporidiosis </li></ul>
  • 184. 79.0 Case 7 62M: History of treated acute myeloid leukemia. Testicular mass
  • 185. 79.1 Case 7
  • 186. 79.2 Case 7
  • 187. 79.3 Case 7 b
  • 188. 79.4 Case 7 c
  • 189. 79.5 <ul><li>a. What is the diagnosis? </li></ul><ul><li>b. Name the stain </li></ul><ul><li>c. Name the stain </li></ul>
  • 190. 79.6 <ul><li>Case 7 . </li></ul><ul><li>2 a. What is the diagnosis? Seminoma </li></ul><ul><li>1 b. Name the stain: Oct3/4 </li></ul><ul><li>1 c. Name the stain: PLAP/C-Kit </li></ul>
  • 191. 38.0 Case 8 32F: No history provided
  • 192. 38.1 Case 8
  • 193. 38.2 Case 8
  • 194. 38.3 Case 8
  • 195. 38.4 Case 8
  • 196. 38.5
  • 197. 38.6 <ul><li>SIL (P16, MIB1) to CIN II/HGSIL </li></ul>
  • 198. 73.0 Case 1 No history
  • 199. 73.1 Case 1
  • 200. 73.2 Case 1
  • 201. 73.3 Case 1 a
  • 202. 73.4 Case 1 b
  • 203. 73.5 <ul><li>Case 1 . A section of breast tissue. Name the stains. </li></ul>
  • 204. 73.6 <ul><li>1 a. ER/PR </li></ul><ul><li>1 b. SMA/Smooth muscle heavy chain myosin/Caldesmon </li></ul>
  • 205. 101.0 Middle aged woman Enormously enlarged unilateral multiloculated ovarian mass Smooth lining, viscous contents Case 4
  • 206. 101.1 Case 4
  • 207. 101.2 Case 4
  • 208. 101.3 Case 4
  • 209. 101.4 Case 4
  • 210. 101.5 Case 4
  • 211. 101.6
  • 212. 101.7 <ul><li>Mucinous cystadenoma </li></ul>
  • 213. 110.0 62 F Two masses in the ovary. The first is homogenous, white and firm It measures 2.5 x 1 x 1 cm Case 13a
  • 214. 110.1 Case 13a
  • 215. 110.2 Case 13a
  • 216. 110.3 Case 13a
  • 217. 110.4 Case 13a
  • 218. 110.5 Case 13a
  • 219. 110.6
  • 220. 110.7 <ul><li>Fibroma </li></ul>
  • 221. 111.0 The other mass is cystic with a smooth lining and an intramural nodule. The cyst lining is smooth I made that up because somebody did not comment on the lining Case 13b
  • 222. 111.1 Case 13b
  • 223. 111.2 Case 13b
  • 224. 111.3 Case 13b
  • 225. 111.4 Case 13b
  • 226. 111.5 Case 13b
  • 227. 111.6 Case 13b
  • 228. 111.7
  • 229. 111.8 <ul><li>Brenner tumor </li></ul>
  • 230. 43.0 Case 13 Calcifications in breast
  • 231. 43.1 Case 13 0.2 cm
  • 232. 43.2 Case 13
  • 233. 43.3 Case 13
  • 234. 43.4 Case 13
  • 235. 43.5 Case 13
  • 236. 43.6 Case 13
  • 237. 43.7
  • 238. 43.8 <ul><li>ADH from columnar lesion; Ca++ </li></ul>
  • 239. 103.0 32F Unilateral enlarged ovary Approximately 7.0 cm Cystic and solid Case 6
  • 240. 103.1 Case 6
  • 241. 103.2 Case 6
  • 242. 103.3 Case 6
  • 243. 103.4 Case 6
  • 244. 103.5 Case 6
  • 245. 103.6
  • 246. 103.7 <ul><li>Sertoli Leydig cell tumor </li></ul>
  • 247. 74.0 Case 2 49F: Breast biopsy for calcifications.
  • 248. 74.1 Case 2
  • 249. 74.2 Case 2
  • 250. 74.3 Case 2
  • 251. 74.4 Case 2
  • 252. 74.5 Case 2
  • 253. 74.6 Case 2
  • 254. 74.7 <ul><li>a. Name the stai n </li></ul><ul><li>b. Most comprehensive diagnosis on sections provided: </li></ul>
  • 255. 74.8 <ul><li>Case 2 . </li></ul><ul><li>1 a. Name the stai n: E-cadherin </li></ul><ul><li>2 b. Most comprehensive diagnosis on sections provided: </li></ul><ul><li>Low grade DCIS </li></ul><ul><li>LCIS with comedo necrosis </li></ul><ul><li>Calcifications present in LCIS </li></ul>
  • 256. 5.0 Case 5 History of DCIS in this breast
  • 257. 5.1 Case 5
  • 258. 5.2 Case 5
  • 259. 5.3 Case 5
  • 260. 5.4 Case 5
  • 261. 5.5 Case 5
  • 262. 5.6 Case 5
  • 263. 5.7
  • 264. 5.8 <ul><li>Radial scar, calcifications present </li></ul>
  • 265. 14.0 Case 14 No history
  • 266. 14.1 Case 14
  • 267. 14.2 Case 14
  • 268. 14.3 Case 14
  • 269. 14.4 Case 14
  • 270. 14.5 Case 14
  • 271. 14.6 Case 14
  • 272. 14.7
  • 273. 14.8 <ul><li>Well diff neuroendocrine tumor </li></ul>
  • 274. 9.0 Case 9 Mastectomy specimen
  • 275. 9.1 Case 9
  • 276. 9.2 Case 9
  • 277. 9.3 Case 9
  • 278. 9.4 Case 9
  • 279. 9.5 Case 9
  • 280. 9.6
  • 281. 9.7 <ul><li>Peripheral papillomas </li></ul>
  • 282. 90.0 Case 3 43F: Tumor, right wrist
  • 283. 90.1 Case 3
  • 284. 90.2 Case 3
  • 285. 90.3 Case 3
  • 286. 90.4 Case 3
  • 287. 90.5 Case 3
  • 288. 90.6
  • 289. 90.7
  • 290. 75.0 Case 3 55M: Tonsillar mass
  • 291. 75.1 Case 3
  • 292. 75.2 Case 3
  • 293. 75.3 Case 3
  • 294. 75.4 Case 3
  • 295. 75.5 <ul><li>a. Most comprehensive diagnosis on sections provided </li></ul><ul><li>b. Name the stain </li></ul>
  • 296. 75.6 <ul><li>Case 3 . </li></ul><ul><li>2 a. Most comprehensive diagnosis on sections provided: </li></ul><ul><li>Basaloid squamous cell carcinoma </li></ul><ul><li>2 b. Name the stain: P16 </li></ul>

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