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SOLO review 2011 part 1
 

SOLO review 2011 part 1

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    SOLO review 2011 part 1 SOLO review 2011 part 1 Presentation Transcript

    • 0.0
      • Case order is randomized
      • A blank page precedes every diagnosis
      • Every diagnosis is verbatim from answer key
      • Case numbers
        • 1-15: July 2010
        • 16-30: August 2010
        • 31-50: September 2010
        • 51-72: November 2010
        • 73-87: February 2011
        • 88-97: April 2011
        • 98-113: May 2011
    • 16.0 57F, hysterectomy for uterine prolapse Case 1
    • 16.1 Case 1
    • 16.2 Case 1
    • 16.3 Case 1
    • 16.4
    • 16.5
      • Cervical atrophy
    • 22.0 Case 7 32F, LGSIL on Pap, HPV DNA+ by history. Biopsy from cervix.
    • 22.1 Case 7
    • 22.2 Case 7
    • 22.3
    • 22.4
      • Unremarkable ectocervix
    • 83.0 Case 11 49M: Retroperitoneal/mesenteric mass
    • 83.1 Case 11
    • 83.2 Case 11
    • 83.3 Case 11
    • 83.4 Case 11
    • 83.5 Case 11
    • 83.6 Case 11
    • 83.7
      • Diagnosis
      • Name the stain
    • 83.8
      • Case 11 .
      • 2 Diagnosis: Fibromatosis
      • 1 Name the stain: B-catenin
    • 12.0 Case 12 FNA palpable breast mass
    • 12.1 Case 12
    • 12.2 Case 12
    • 12.3
    • 12.4
      • Fibroadenoma
    • 105.0 Bilateral ovarian masses Case 8
    • 105.1 Case 8
    • 105.2 Case 8
    • 105.3 Case 8
    • 105.4 Case 8
    • 105.5
    • 105.6
      • Serous borderline tumor, typical
    • 60.0 61F: Once again, a mass in front of the ear Case 10
    • 60.1 Case 10
    • 60.2 Case 10
    • 60.3 Case 10
    • 60.4 Case 10
    • 60.5 Case 10
    • 60.6
    • 60.7
      • Myoepithelial carcinoma dd clear cell carcinoma, RCC, HCC but you would have to discuss and exclude (immunos for former, vascularity for latter)
    • 78.0 Case 6 An invasive mammary carcinoma
    • 78.1 Case 6
    • 78.2 Case 6
    • 78.3
      • a. Name the stain
    • 78.4
      • Case 6 . An immunostain performed on an invasive breast carcinoma.
      • 2 a. Name the stain: Her-2
    • 26.0 46F Endometrial biopsy Case 11
    • 26.1 Case 11
    • 26.2 Case 11
    • 26.3 Case 11
    • 26.4 Case 11
    • 26.5 Case 11
    • 26.6
    • 26.7
      • Extreme exogenous hormonal influence (progesterone)
    • 24.0 Case 9 23 F, cervical biopsy
    • 24.1 Case 9
    • 24.2 Case 9
    • 24.3
    • 24.4
      • HGSIL/CIN II
    • 57.0 6M: Enlarged retro-auricular lymph node Case 7
    • 57.1 Case 7
    • 57.2 Case 7
    • 57.3 Case 7
    • 57.4 Case 7
    • 57.5
    • 57.6
      • Langerhan cell histriocytosis
    • 18.0 55F complains of vulvar irritation Vulva biopsy Case 3
    • 18.1 Case 3
    • 18.2 Case 3
    • 18.3 Case 3
    • 18.4
    • 18.5
      • VIN3 with microinvasion
    • 113.0 46F Each ovary measures approximately 4 x 3 x 3 cm. Cut surface is white and bosselated. Case 15
    • 113.1 Case 15
    • 113.2 Case 15
    • 113.3 Case 15
    • 113.4 Case 15
    • 113.5
    • 113.6
      • Metastatic lobular carcinoma
    • 77.0 Case 5 No history
    • 77.1 Case 5
    • 77.2 Case 5
    • 77.3 Case 5
    • 77.4 Case 5
    • 77.5 Case 5
    • 77.6
      • a. Name the stain
      • b. What is the diagnosis?
    • 77.7
      • Case 5 .
      • 1 a. Name the stain: S-100
      • 2 b. What is the diagnosis? Benign lymph node; no melanoma
    • 85.0 Case 13 66M: Elevated PSA
    • 85.1 Case 13
    • 85.2 Case 13
    • 85.3 Case 13
    • 85.4 Case 13
    • 85.5 Case 13
    • 85.6 Case 13
    • 85.7
      • a. Most comprehensive diagnosis on sections provided
      • b. Name the stain
    • 85.8
      • Case 13 .
      • 2 a. Most comprehensive diagnosis on sections provided:
      • Ductal adenocarcinoma Gleason 4+4 score 8. Perineural invasion is present
      • 1 b. Name the stain: P63
    • 63.0 62F: Increasing abdominal girth Case 13
    • 63.1 Case 13
    • 63.2 Case 13
    • 63.3 Case 13
    • 63.4 Case 13
    • 63.5 Case 13
    • 63.6 Case 13
    • 63.7
    • 63.8
      • Mucinous adenocarcinoma adherent/metastatic to spleen depending on whether you think that it is in the organ or not
    • 99.0 Bilateral cystic ovarian masses Case 2
    • 99.1 Case 2
    • 99.2 Case 2
    • 99.3 Case 2
    • 99.4 Case 2
    • 99.5 Case 2
    • 99.6 Case 2
    • 99.7 Case 2
    • 99.8
    • 99.9
      • Serous papillary cystadenofibroma
    • 50.0 Case 20 45M: Dysphagia
    • 50.1 Case 20
    • 50.2 Case 20
    • 50.3 Case 20
    • 50.4 Case 20
    • 50.5
    • 50.6
      • Herpses esophagitis
    • 112.0 43F Left ovarian mass 16 x 14 x 11 cm, 1139 gms Solid and cystic cut surface Case 14
    • 112.1 Case 14
    • 112.2 Case 14
    • 112.3 Case 14
    • 112.4 Case 14
    • 112.5 Case 14
    • 112.6 Case 14
    • 112.7 Case 14
    • 112.8 Case 14
    • 112.9
    • 112.10
      • Clear cell carcinoma
    • 30.0 28F: Tissue designated as endometrial polyp Case 15
    • 30.1 Case 15
    • 30.2 Case 15
    • 30.3 Case 15
    • 30.4 Case 15
    • 30.5 Case 15
    • 30.6 Case 15
    • 30.7
    • 30.8
      • Proliferative endometrium
    • 94.0 Case 7 64F
    • 94.1 Case 7
    • 94.2 Case 7
    • 94.3 Case 7
    • 94.4 Case 7
    • 94.5 Case 7
    • 94.6
    • 94.7
    • 45.0 Case 15 20M: Rectal biopsy
    • 45.1 Case 15
    • 45.2 Case 15
    • 45.3 Case 15
    • 45.4
    • 45.5
      • Non-nec granulomas AFB, GMS, r/o Crohn’s
    • 109.0 Cystic ovarian mass Case 12
    • 109.1 Case 12
    • 109.2 Case 12
    • 109.3 Case 12
    • 109.4
    • 109.5
      • Serous borderline tumor micropapillary
    • 2.0 Case 2 28F: Right breast mass
    • 2.1 Case 2
    • 2.2 Case 2
    • 2.3 Case 2
    • 2.4 Case 2
    • 2.5 Case 2
    • 2.6
    • 2.7
      • Lactational change
    • 80.0 Case 8 49M: Resection for metastases.
    • 80.1 Case 8
    • 80.2 Case 8
    • 80.3 Case 8
    • 80.4 Case 8
    • 80.5
      • a. Name the organ
      • b. What is/are the most likely primary site(s ) ?
      • c. This immunostain supports the phenotype of the metastasis. Name the stain
    • 80.6
      • Case 8 .
      • 1 a. Name the organ: Liver
      • 2 b. What is/are the most likely primary site(s ) ?
      • Esophagus, lung, head and neck
      • 1 c. This immunostain supports the phenotype of the metastasis.
      • Name the stain: P63
    • 72.0 Diarrhea Case 22
    • 72.1 Case 22
    • 72.2 Case 22
    • 72.3 Case 22
    • 72.4
    • 72.5
      • cryptosporidiosis
    • 79.0 Case 7 62M: History of treated acute myeloid leukemia. Testicular mass
    • 79.1 Case 7
    • 79.2 Case 7
    • 79.3 Case 7 b
    • 79.4 Case 7 c
    • 79.5
      • a. What is the diagnosis?
      • b. Name the stain
      • c. Name the stain
    • 79.6
      • Case 7 .
      • 2 a. What is the diagnosis? Seminoma
      • 1 b. Name the stain: Oct3/4
      • 1 c. Name the stain: PLAP/C-Kit
    • 38.0 Case 8 32F: No history provided
    • 38.1 Case 8
    • 38.2 Case 8
    • 38.3 Case 8
    • 38.4 Case 8
    • 38.5
    • 38.6
      • SIL (P16, MIB1) to CIN II/HGSIL
    • 73.0 Case 1 No history
    • 73.1 Case 1
    • 73.2 Case 1
    • 73.3 Case 1 a
    • 73.4 Case 1 b
    • 73.5
      • Case 1 . A section of breast tissue. Name the stains.
    • 73.6
      • 1 a. ER/PR
      • 1 b. SMA/Smooth muscle heavy chain myosin/Caldesmon
    • 101.0 Middle aged woman Enormously enlarged unilateral multiloculated ovarian mass Smooth lining, viscous contents Case 4
    • 101.1 Case 4
    • 101.2 Case 4
    • 101.3 Case 4
    • 101.4 Case 4
    • 101.5 Case 4
    • 101.6
    • 101.7
      • Mucinous cystadenoma
    • 110.0 62 F Two masses in the ovary. The first is homogenous, white and firm It measures 2.5 x 1 x 1 cm Case 13a
    • 110.1 Case 13a
    • 110.2 Case 13a
    • 110.3 Case 13a
    • 110.4 Case 13a
    • 110.5 Case 13a
    • 110.6
    • 110.7
      • Fibroma
    • 111.0 The other mass is cystic with a smooth lining and an intramural nodule. The cyst lining is smooth I made that up because somebody did not comment on the lining Case 13b
    • 111.1 Case 13b
    • 111.2 Case 13b
    • 111.3 Case 13b
    • 111.4 Case 13b
    • 111.5 Case 13b
    • 111.6 Case 13b
    • 111.7
    • 111.8
      • Brenner tumor
    • 43.0 Case 13 Calcifications in breast
    • 43.1 Case 13 0.2 cm
    • 43.2 Case 13
    • 43.3 Case 13
    • 43.4 Case 13
    • 43.5 Case 13
    • 43.6 Case 13
    • 43.7
    • 43.8
      • ADH from columnar lesion; Ca++
    • 103.0 32F Unilateral enlarged ovary Approximately 7.0 cm Cystic and solid Case 6
    • 103.1 Case 6
    • 103.2 Case 6
    • 103.3 Case 6
    • 103.4 Case 6
    • 103.5 Case 6
    • 103.6
    • 103.7
      • Sertoli Leydig cell tumor
    • 74.0 Case 2 49F: Breast biopsy for calcifications.
    • 74.1 Case 2
    • 74.2 Case 2
    • 74.3 Case 2
    • 74.4 Case 2
    • 74.5 Case 2
    • 74.6 Case 2
    • 74.7
      • a. Name the stai n
      • b. Most comprehensive diagnosis on sections provided:
    • 74.8
      • Case 2 .
      • 1 a. Name the stai n: E-cadherin
      • 2 b. Most comprehensive diagnosis on sections provided:
      • Low grade DCIS
      • LCIS with comedo necrosis
      • Calcifications present in LCIS
    • 5.0 Case 5 History of DCIS in this breast
    • 5.1 Case 5
    • 5.2 Case 5
    • 5.3 Case 5
    • 5.4 Case 5
    • 5.5 Case 5
    • 5.6 Case 5
    • 5.7
    • 5.8
      • Radial scar, calcifications present
    • 14.0 Case 14 No history
    • 14.1 Case 14
    • 14.2 Case 14
    • 14.3 Case 14
    • 14.4 Case 14
    • 14.5 Case 14
    • 14.6 Case 14
    • 14.7
    • 14.8
      • Well diff neuroendocrine tumor
    • 9.0 Case 9 Mastectomy specimen
    • 9.1 Case 9
    • 9.2 Case 9
    • 9.3 Case 9
    • 9.4 Case 9
    • 9.5 Case 9
    • 9.6
    • 9.7
      • Peripheral papillomas
    • 90.0 Case 3 43F: Tumor, right wrist
    • 90.1 Case 3
    • 90.2 Case 3
    • 90.3 Case 3
    • 90.4 Case 3
    • 90.5 Case 3
    • 90.6
    • 90.7
    • 75.0 Case 3 55M: Tonsillar mass
    • 75.1 Case 3
    • 75.2 Case 3
    • 75.3 Case 3
    • 75.4 Case 3
    • 75.5
      • a. Most comprehensive diagnosis on sections provided
      • b. Name the stain
    • 75.6
      • Case 3 .
      • 2 a. Most comprehensive diagnosis on sections provided:
      • Basaloid squamous cell carcinoma
      • 2 b. Name the stain: P16