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Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
Prostate disease
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Prostate disease

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  • 1. Prostate Disease Important information for men !
  • 2. Test your prostate knowledge
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  • 5. 3 most common disease of the prostate <ul><li>Benign Prostatic Hyperplasia </li></ul><ul><li>Prostate Cancer </li></ul><ul><li>Prostatitis (inflammation of the prostate) </li></ul><ul><li>Important ! </li></ul><ul><li>Men > 35years old should be aware of these problems. </li></ul>
  • 6. What is the prostate? <ul><li>Small gland, size & shape of chestnut </li></ul><ul><li>20g, 1.2 inches </li></ul><ul><li>Situated below the bladder, surrounding the urethra. Urethra is the passage that carries the urine from the bladder through the penis during urination. </li></ul><ul><li>Important! </li></ul><ul><li>Women do not have prostate. </li></ul>
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  • 8. What is the function of the prostate? <ul><li>Secretes fluid that forms part of the semen. </li></ul><ul><li>Prostate fluid provides nourishment and energy for the sperm to be active and be able to ‘swim’. </li></ul>
  • 9. How do I know if I have a prostate problem? <ul><li>The following symptoms suggest a prostate problem:- </li></ul><ul><li>Frequent urination </li></ul><ul><li>Waking up at night to urinate </li></ul><ul><li>Unable to postpone urination </li></ul><ul><li>Feeling being unable to empty the bladder </li></ul><ul><li>Delay in starting to urinate </li></ul><ul><li>Weak urination stream – straining </li></ul><ul><li>Intermittent stream – stopping & starting </li></ul><ul><li>Incontinence – loss of urinary control </li></ul>
  • 10. Other symptoms:- <ul><li>Painful urination </li></ul><ul><li>Blood in urine </li></ul><ul><li>BPH and prostate cancer can cause similar symptoms but early prostate cancer does NOT produce any symptoms. </li></ul>
  • 11. What is Benign Prostatic Hyperplasia? <ul><li>With increasing age, the prostate tissue will grow and thicken. </li></ul><ul><li>Normal weight 20g 150g </li></ul><ul><li>BPH is present in 80% of 60 year old men. </li></ul><ul><li>Changes due to change in hormone as men age and environmental factors </li></ul><ul><li>Eg) Diet. </li></ul>
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  • 13. How is BPH diagnosed? <ul><li>Digital examination </li></ul>
  • 14. <ul><li>If there are any lumps, the doctor will suggest other tests </li></ul><ul><li>eg) urinalysis, biopsy, blood test, </li></ul><ul><li>Treatment?? </li></ul><ul><li>Prostatectomy – remove inner obstruction ( TURP ) </li></ul><ul><li>Drugs to shrink or relax prostate. </li></ul><ul><li>Microwaves treatments, prostate stents, lasers </li></ul>
  • 15. Prostate cancer <ul><li>Most common cancer in elderly men and the 2 nd most common cause of cancer-related death in men. </li></ul>
  • 16. What is cancer? <ul><li>Cells in the body normally grow in an organized, controlled manner with new cells replacing dying cells. </li></ul><ul><li>When this control is lost, cells can grow rapidly and abnormally, forming a tumor or growth. </li></ul><ul><li>Some of these are called benign because they grow slowly and do not spread elsewhere in the body. </li></ul>
  • 17. <ul><li>Other tumors invade and destroy normal tissue and spread (metastasize) to other parts of the body where they can grow. </li></ul><ul><li>These tumors are malignant and are called cancerous cells. When they spread to other parts of the body, they are called metastases. </li></ul>
  • 18. What is prostate cancer? <ul><li>Cancer of the prostate. </li></ul><ul><li>Early stages causes no symptoms </li></ul><ul><li>This cancer can spread to lymph nodes and blood circulation causing cancer in other parts of the body. Eg) bones </li></ul><ul><li>BPH & cancer can occur together in the prostate. </li></ul>
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  • 23. How is prostate cancer detected? <ul><li>DRE reveals a lump. </li></ul><ul><li>Blood test is abnormal, prostate specific antigen (PSA). </li></ul><ul><li>Not all lump is a cancer. PSA is produced by prostate. Level suspicious. </li></ul><ul><li>Prostate biopsy. </li></ul><ul><li>Transrectal ultrasound ( TRUS ) </li></ul>
  • 24. Treatment <ul><li>Surgical removal </li></ul><ul><li>Radiation therapy </li></ul><ul><li>Hormonal therapy </li></ul>Early detection and prevention is still the best !
  • 25. Prostatitis <ul><li>3 types of prostatitis:- </li></ul><ul><li>Acute bacterial prostatitis </li></ul><ul><li>Chronic bacterial prostatitis </li></ul><ul><li>Non-bacterial prostatitis </li></ul>
  • 26. How is prostatitis diagnosed? <ul><li>DRE </li></ul><ul><li>Urine specimens </li></ul><ul><li>Treatment? </li></ul><ul><li>Antibiotics </li></ul><ul><li>Muscle relaxants </li></ul><ul><li>Anti-inflammatory </li></ul>
  • 27. Supplements shown to help prevent and reduce prostate problems. <ul><li>Widely used in other countries to treat BPH. 50% treatment in Italy and 90% treatments in Germany. </li></ul><ul><li>Reduce symptoms of BPH. </li></ul><ul><li>Similar efficacy to medications such as finasteride ( Proscar ). Better tolerated & less expansive. </li></ul><ul><li>American Family Physician 2003; 67:1281-3, 2003) </li></ul>Saw Palmetto
  • 28. Broccoli Contains chemicals that block growth of human prostate cancer cells and aid in cancer prevention. Major compound, indole-3-carbinol ( 13C ) have cancer prevention properties. 13C converted to DIM, which acts as powerful male hormone blocker and stops prostate cancer cells from growing and dividing. Dihydrotestosterone ( DHT ) is the primary male hormone that causes prostate cancer. Journal of Biological Chemistry, University of California, June 6, 2003
  • 29. Pygeum <ul><li>First used by Zulu tribe in Africa. </li></ul><ul><li>Most popular treatment for symptoms of BPH in France, Italy and America. </li></ul><ul><li>Worldwide demand increased, in 1998 it was a threatened species. </li></ul><ul><li>Inhibits binding of DHT to receptors. </li></ul><ul><li>Reduce symptoms of mild to moderate BPH. </li></ul><ul><li>Good tolerability. </li></ul>
  • 30. Soya and Isoflavones <ul><li>In 1990, the US National Cancer Institute allocated USD 3 million to study anti-cancer properties of soy. </li></ul><ul><li>Soya bean isoflavones, genistin inhibits growth of all types of cancer cells. </li></ul><ul><li>It also reduce and inhibit prostate tumor development and growth. </li></ul><ul><li>1 serving of soya per day was associated with 70% reduction in prostate cancer. </li></ul><ul><li>Isoflavones also responsible in preventing progression of latent prostate cancer to the more advance form of cancer. </li></ul>
  • 31. Zinc and Selenium <ul><li>Important for normal cellular function. </li></ul><ul><li>Dosage is important. Recommended:- </li></ul><ul><li>Zinc = 11mg – 40 mg/day </li></ul><ul><li>Selenium = 55 – 400 mg/day </li></ul><ul><li>American Institute of Medicine of the National Academies, Dietary reference intakes. </li></ul>
  • 32. Calcium d-Glucarate <ul><li>A form of glucaric acid. Enhances process of glucuronidation, a process by which the body rids itself of dangerous carcinogens and harmful chemicals. </li></ul><ul><li>Non-toxic, natural substance in fruits and vegetables. </li></ul><ul><li>Highly protective against cancer – lung, skin, liver, breast, colon and prostate. Reduce cancer by 60% ( Walaszek, 1990 ) </li></ul><ul><li>Enhance the detoxification of carcinogens and androgens and inhibits prostate cancer. </li></ul><ul><li>M.D Anderson Cancer Centre, No.2 cancer center in USA. </li></ul>
  • 33. Lycopene <ul><li>Anti-cancer properties </li></ul>
  • 34. Zinc & Selenium Saw Palmetto Isoflavones Lycopene Pygeum Extract Nettle Extract Soya Bean Extract Broccoli Extract Calcium d-Glucarate
  • 35. 4Life Targeted Transfer Factor <ul><li>Helps keep the immune system efficient. </li></ul><ul><li>From cow colostrum and chicken egg yolk. </li></ul><ul><li>Small protein 10,000 Daltons. </li></ul><ul><li>Simple protein, easily absorbed. Goes directly into blood stream and lymphatics to immune cells. </li></ul><ul><li>Educate immune cells to recognize, respond and remember invaders. </li></ul>
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