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Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
Dyslipidemia case study
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Dyslipidemia case study

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Dyslipidemia case study

Dyslipidemia case study

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  1. Male patient aged 35 ys C/o of skin lesions over the extensor surface of both elbows and knees
  2. Bp 130/80, pulse 80 regular Neck Chest Heart AbdNS
  3. Lab Values Total cholesterol 508 mg% Trigliceride 2894 Random Sugar 338 ECG T wave changes in LIII, aVF,V3-V6
  4. Ask patient 3 questions Family history DM, Dyslipedimia Early IHD in family Thyroid disease Drug intake Liver,kidney diseases
  5. Inferiolateral ischemia
  6. Investigations recomended Lipid profile Liver function Renal function Thyroid function Cardiology consultation Why?
  7. Causes of secondary hyperlipidemia Cholestatic liver diseases Nephrotic syndrome Chronic renal failure Hypothyroidism Cigarette smoking Obesity Drugs
  8. Expected complications IHD, accelerated atherosclerosis Pancreatitis Gall bladder disease Related to medications Complications of Diabetes
  9. Lipoprotein
  10. Type of lipoproteins
  11. Lipoproteins suclasses
  12. Dyslipedimia
  13. Lipid Fredrekhsen classification
  14. Plan of your treatment Diet Diabetes control IHD, accelerated atherosclerosis Hypolipemic medications,Statin,Fibrate,Resin uptake,ezetimibe, nicotinic acid,lipid apheresis others
  15. Mechanism of action Statins Are specific competitive inhibitors of microsomal enzyme HMG-CoA reductase, which catalyses the conversion HMG-Co ATo mevalonate, a rate- determining step in cholesterol synthesis
  16. Mechanism of action of Fibrates
  17. ADR of Statins Statins , Rhabdomyalgia , Rhabdomyolysis Renal impairement Raise transaminases GIT
  18. APHERESIS

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