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  1. 1. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page F3 FR A N K H. N E T T E R, M. D. I N T E R A C T I V E ATLAS OF CLINICAL ANATOMY USER’S GUIDE F3
  2. 2. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page F4 © 1997-98 Novartis, 556 Morris Avenue, Summit, NJ 07901, for artwork, text, and packaging. All rights reserved. © 1997-98 DxR Development Group, Inc., 150 East Pleasant Hill Road, Carbondale, IL 62901, for software template, screen designs, and icons. All rights reserved. No part of this CD-ROM publication, including artwork, text, and software, may be utilized, reproduced, stored, or transmitted in any form or by any means, electronic or mechanical, or by any information storage or retrieval system, without permission in writing from the copyright holder. Address inquiries to Novartis Pharmaceuticals Corporation, Novartis Medical Education, 556 Morris Avenue, Summit, NJ 07901. Macintosh® is a registered mark of Apple Computer, Inc. Windows™ is a trademark of Microsoft. Portions of the Macintosh version of the Interactive Atlas of Clinical Anatomy were created using SuperCard®, © 1989–1996 Allegiant Technologies, Inc. Portions of the Windows version of the Interactive Atlas of Clinical Anatomy were created using Toolbook® II, © 1992–1996 Asymetrix Corporation. The Visible Human movies were created from data obtained from Research Systems’ Visible Human CD. The original data are from the Visible Human Project™ provided by the National Library of Medicine. CT reformations and high-resolution CT images were provided courtesy of Elscint, Inc. Zurich™ Font is copyright Bitstream, Inc. Brands and product references noted are the trademarks of their respective companies. Design by Kingswood Advertising, Inc., Ardmore, PA. F4
  3. 3. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page F5 I N T E R A C T I V E ATLAS OF CLINICAL ANATOMY Illustrations Frank H. Netter, M.D. and John A. Craig, M.D. Carlos Machado, M.D. Content and Text Development Arthur F. Dalley II, Ph.D. Professor of Anatomy Creighton University School of Medicine Omaha, Nebraska Software Development J. Hurley Myers, Ph.D. Professor of Physiology and Internal Medicine Southern Illinois University School of Medicine Carbondale, Illinois Radiology Editor Michael R. Williamson, M.D. Professor of Radiology The University of New Mexico Health Sciences Center Albuquerque, New Mexico
  4. 4. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page F6 CONTRIBUTORS Terminology Reviewers Robert J. Leonard, Ph.D. Division of Biomedical Sciences University of California, Riverside Riverside, California Duane Haines, Ph.D. Department of Anatomy University of Mississippi Medical Center Jackson, Mississippi F6
  5. 5. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page F7 CONTENTS Page From the Publisher . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . i Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ii Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . iii HOW TO FIND HELP IN THIS PROGRAM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Manual Tutorials On-line Help Hotline HOW TO MAKE THE MOST OF THIS PROGRAM . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Students Practice Tests Pronunciation of Terms Anatomy in a Clinical Setting Instructors Integrated Approach Compare Screens Study Guide and Plate Notes Tests Create-A-Show Medical Professionals Quick Reference Staff Training Patient Education WHAT THIS PROGRAM CONTAINS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Visual Content Navigational Features Educational Features Tutorials Study Preparation Buttons Plate Control Buttons LICENSE AGREEMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 INSTALLING AND RUNNING THE PROGRAM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 F7
  6. 6. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page i FROM THE PUBLISHER In January 1997, a historic event within the pharmaceutical industry took place, when Ciba-Geigy Corporation merged with Sandoz Pharmaceuticals to form Novar- tis Pharmaceuticals Corporation. In this merger, Ciba Medical Education became Novartis Medical Education. Although our name has changed, our prime objective remains the same: to provide high-quality, relevant educational resources for the medical community. The Interactive Atlas of Clinical Anatomy is our first release under the Novartis name. This work is actually our response to recommendations we received from you, our associates. When we published the Interactive Atlas of Human Anatomy in August 1995, we achieved a milestone of our own. The Interactive Atlas was our first entry into the field of interactive medical education, and it was well received, indeed, hugely successful. Students, instructors, and practitioners alike gave this work high marks. Soon after its release, the Interactive Atlas, like its parent soft- cover anatomy book, became the favorite of students of anatomy everywhere. But the Interactive Atlas seemed to have whetted the appetite for more. We received many requests for an electronic atlas that would include imaging data and clinical material to complement the anatomical plates. And so, drawing from our extensive archive of medical art published over the years in The Ciba Collection of Medical Illustrations and Clinical Symposia, and from noteworthy outside sources, we developed the Interactive Atlas of Clinical Anatomy, replete with visualizations of the human body in various media, concise explanatory texts, and meaningful educational features. You asked for a practical, useful atlas of clinical anatomy, and we responded. It is not possible to describe the enormous amount of work involved in putting together a program of this complexity. We are grateful for the efforts of many dedicated people: the tireless, extraordinary Dr. Arthur F. Dalley II, at Creighton Uni- versity; Dr. J. Hurley Myers and his team at DxR Development Group, Inc.; and the Clinical Atlas team at Novartis, all of whom accepted nothing but the best, especially from themselves. We hope our new electronic atlas fulfills your expectations. We welcome your comments and suggestions as we continue our long-term commitment to medical education. Peter Carlin Executive Director, Health Policy and Medical Education From the Publisher i
  7. 7. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page ii PREFACE As with the initial Interactive Atlas of Human Anatomy, it was once again a pleasure to work with Dr. Arthur Dalley, the editors of Novartis Medical Education, and the devel- opment team of the DxR Group to create what is sure to be a significant addition to the teaching and learning of human anatomy. To create this new program, we reached deep into the vaults at Novartis to find Netter illustrations that provide important corre- lations to many of the anatomical plates used in the Interactive Atlas. In addition, Dr. Michael Williamson provided the majority of the relevant radiographs, and Novartis commissioned their current artists to create key cross sections, which complement the data we have included from the Visible Human Project™. The result is a new work, with thousands of illustrations, enhanced with explanatory texts written by Dr. Dalley to explain the relationship between anatomical and correlating clinical images. As we developed the Interactive Atlas of Clinical Anatomy, we discovered that with additional information and features comes a greater need to understand how to use, organize, and manage the learning material. To aid with this task, we have provided three avenues of assistance. The narrated tutorials give an overview of important user features and show how they function. The Help section, available from every screen in the program, deals concisely and immediately with “how-to” issues related to the spe- cific features of the Atlas. Finally, this manual contains a quick-reference glossary of the key features of the Clinical Atlas with only the briefest explanation of how they work. The Clinical Atlas has some special features for students, such as spoken labels and a Study Guide that allows for individual customization. In addition, there are a couple of “teacher features” that make the Clinical Atlas an important adjunct to anatomy educa- tion. The classroom teacher who gives slide presentations using Netter illustrations will appreciate the Create-A-Show feature. Now you can export illustrations from the Clinical Atlas directly into the Create-a-Show application where you can organize, modify, enhance, and supplement the imported images using a built-in paint utility. Moreover, you will be able to import electronic images from other sources into Create- A-Show, so you can go to class with one file containing your electronic lecture edited and organized the way you want to present it. Many instructors use Netter illustrations to evaluate a student’s knowledge of anatomy. The Exam Record Utility provides an easy way to review and evaluate the results of large classes of anatomy students—it is the teacher’s best friend. We encourage you to explore these features and the enormous amount of anatomi- cal material in the Clinical Atlas to discover how it works best for you. As always, we welcome your reactions to our programs as we strive to develop powerful and practi- cal tools to enhance your study and teaching of medical science. J. Hurley Myers, Ph.D. Professor of Physiology and Internal Medicine Preface ii
  8. 8. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page iii FOREWORD The anatomical illustrations of Frank H. Netter, M.D., have been used extensively in medical and health sciences education for decades but were not readily available to students until 1989, when Dr. Netter’s Atlas of Human Anatomy was published. Almost immediately, the Atlas became the top-selling anatomical atlas in the world, and clearly has become the students’ choice. The clinical, functional, and procedur- al artwork by Dr. Netter has also appeared over the years. There is hardly a clinical course, continuing education event, or health professional association meeting today that does not include these illustrations, yet these, too, have had limited availability to students. I am very excited to play a part in bringing more Netter art- work—and new artwork in the Netter style—to today’s students of medicine and all the health sciences. Recent years have seen a revolution in the health sciences curricula, once clearly divided into basic science and clinical components. Clinical application has become increasingly integrated into the teaching of the basic sciences, and vice versa, making learning of the basics more acceptable, efficient, and even exciting when its relevance and application can be appreciated. Similarly, recent dramatic developments in medical imaging have made the demonstration of internal anatomy—in the living patient—both increasingly routine and important in diag- nosis and treatment. A natural integration of gross and radiologic anatomy has resulted from this. Parallel developments in technology have also added new options and approaches to the way that information can be presented and learned. Thus, the time is right for introduction of a teaching and learning instrument that combines all of these things: a clinically oriented, interactive atlas of human gross and radiologic anatomy on CD-ROM. Along with these new developments, anatomical terminology has changed. Internationally, Latin and Greek anatomical terms have been replaced with Anglicized forms, in both common usage and scholarly endeavors. The Interactive Atlas of Clinical Anatomy incorporates the most up-to-date standard for anatomical terminol- ogy. Because this terminology is an international standard, and because the Atlas is utilized around the world, the “spoken labels,” although not likely to be an essen- tial feature for all, will prove to be worthwhile for many. An additional motivation for me in this project was a wish to design a practical anatomical reference that extended far beyond first-year courses in terms of informa- tion and utility—a work relevant and useful during the clinical years as well as in prac- tice, making it an investment for a career, not just for a course. In preparing the Clinical Atlas, I always kept in mind that it would be used by many students training for professions other than medicine. The Clinical Atlas thus includes features and Foreword iii
  9. 9. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page iv information useful for any student requiring anatomical knowledge, in fields such as dentistry, radiographic technology, and many other areas of conventional or alterna- tive health care. In addition, several features have been added to make this program worthwhile to educators as well as to their students. While the great majority of what is offered by this work can truly be described as state-of-the-art, there are a few procedures and techniques included which have obviously been superseded by new technology. However, new technologies are not universally available; some of the older techniques remain as standard procedure in some locations. Further, with an increasing population of senior citizens, there is a need to have awareness of procedures patients have previously experienced. All the procedures included represent innovative application of anatomical knowledge. This program is not intended to teach proficiency or the ability to employ any of the techniques or procedures described; its purpose is only to illustrate the clinical application of anatomical knowledge. I sincerely appreciate the efforts of all who contributed to the development of this work. I am especially grateful to our spouses, children, and significant others for their faith in our vision, made evident in their tremendous encouragement and patience. Arthur F. Dalley II, Ph.D. Clinical Anatomist Foreword iv
  10. 10. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 1 HOW TO FIND HELP IN THIS PROGRAM We have provided several avenues for obtaining help in using this program. MANUAL This manual gives you a handy reference describing the visual contents of the program and the navigational and educational features (the main “buttons”). In addi- tion, you can learn how to make the most of this program by reading the special section addressing students, instructors, and medical professionals. TUTORIALS Seeing a demonstration is often an easier way to learn than reading a set of instructions. We have provided five tutorials for you to watch: Getting Started, List Manager, Study Guide, Tests, and Create-A-Show. You can stop and start these tutorials anytime you want, and you can replay the parts you want to review. We suggest that you take advantage of the Getting Started tutorial, which will give you a good overview of the entire program. ON-LINE HELP The on-line help defines all buttons, icons, and menu items and also provides step-by-step instructions for a multitude of tasks related to the features of the pro- gram. Together with the tutorials, the on-line help should provide all the assistance you will need to use the program effectively. HOTLINE Help is available from DxR Development Group, Inc.: Phone: (800) 453-8040 or (618) 453-1140, between 9:00 A.M. and 5:00 P.M. central time, Monday through Friday Fax: (618) 453-5309 E-mail: For more information about medical education software from Novartis, visit our Web site at How to Find Help in This Program 1
  11. 11. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 2 HOW TO MAKE THE MOST OF THIS PROGRAM In preparing the Interactive Atlas of Clinical Anatomy, we sorted through thou- sands of images to select visual material that best exemplified the clinical contexts for the basic gross anatomy as presented in the Atlas of Human Anatomy. We designed the program’s features to give users the most efficient tools for exploring these clinical and anatomical relationships. Users who are familiar with the Interactive Atlas of Human Anatomy will find much in common with that program. The key utilities that were essential in the Interactive Atlas of Human Anatomy —an ability to organize and manage the information contained in the program (the List Manager), a way to facilitate the learning process (the Study Guide), and a vehicle for testing oneself and others (the Tests)—are present in this new, more complex program and, in some cases, have been improved. Following is a synopsis of the main features of the Clinical Atlas program that will be of interest to students, instructors, and medical professionals. STUDENTS Students can derive both short-term and long-term benefits from this program. Of immediate value is that it helps you pass your exams, and, more lastingly, you gain an understanding of the relevance of basic knowledge to clinical medicine, a firm foundation for a career in medicine. Practice Tests It’s no secret that students are motivated by a desire to pass exams. This need at least partially accounts for the great popularity of the print and electronic ver- sions of the Atlas of Human Anatomy. No artist captured the clinical story better than Dr. Netter, and, therefore, the Clinical Atlas should be equally helpful to you in preparing for exam questions that test your knowledge not only of anatomy but also of its clinical meaning. The Interactive Atlas of Clinical Anatomy includes a Practice Test feature that allows you, whenever you are viewing a plate, to test your knowledge quickly by locating the point corresponding to the “test question” label. The Practice Test option can give you hints and show you the right answer. Although the Custom Exam feature was essentially designed for instructors, students can also use it to create different types of practice tests simulating the real tests they will be taking. The Locate Structures format is basically the same as the Practice Test, but, using the custom feature, you can choose to test yourself How to Make the Most of This Program 2
  12. 12. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 3 on any structures you are having difficulty learning. The Name Structures format is particularly useful if you want to learn to spell the anatomical terms correctly, since this format requires you to type in the correct answer. In real testing, your instruc- tor may decide that spelling counts, so you’ll want to be prepared. Pronunciation of Terms We added an audio feature that allows you to hear any of the anatomical labels pronounced. You can click on most anatomical labels to hear the spoken pronunciation. Anatomy in a Clinical Setting The convenience of having a wealth of interrelated clinical material within one anatomy resource is just as valuable to time-pressed students as to instructors. Students who are seeking the greater wisdom that comes from recognizing the clinical significance of basic anatomy will be able to enrich their own learning expe- rience by investigating all of the clinical material that is linked and cross-referenced in this program. INSTRUCTORS Integrated Approach The Interactive Atlas of Clinical Anatomy embodies the approach that instructors in the medical sciences have told us they want to see in educational materials today: basic knowledge presented in the context of practical applications. We chose material which best illustrates a clinical problem that a study of the anatomy helps to clarify. We know that students will see many conditions in their patient encounters that are the result of disruption or dysfunction of the underlying anatomy. Having the clinical problem closely associated with the basic anatomy in the learning process helps students remember the basic anatomy more readily and use it more effec- tively in their diagnostic reasoning. By experiencing this integrated approach to the study of anatomy, they will begin to practice a fundamental problem-solving strate- gy that all medical professionals employ: the use of basic knowledge to help solve clinical problems. This approach to the teaching of anatomy also helps students answer, for themselves, the question they all ask, implicitly or explicitly: Why do I have to know this? How to Make the Most of This Program 3
  13. 13. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 4 Compare Screens Because we linked, or “correlated,” all of the clinical material with its anatomical counterparts, instructors can easily reinforce the integrated approach to learning by using the Clinical Atlas program in the class- room. You can discuss a specific anatomical illustration with the stu- dents and then immediately show them correlated images with associated text that are of importance to healthcare professionals. The “compare” screens let you show this material side by side and easily refer to each component as often as necessary. For example, you can first show a full-screen image of the bronchial tree of the lungs and then, using the com- pare screen, show a bronchogram. The Clinical Atlas program compiles a signifi- cant amount of supplementary material in one convenient place. Study Guide and Plate Notes You can direct students’ learning by preparing Study Guide plates; that is, elimi- nating all but the labels and points that are especially important for them to know and loading these as a special file. You can further guide students by attaching special text or audio notes to plates, in order to record additional observations or highlight the salient points. Tests Instructors will particularly like the testing features. In addition to the simple Practice Test option, there are the more controlled Custom Exam selections. With these, you can click specific labels on many different plates to create a test, or write related questions and then require the students to select one or more points on an illustration to answer the question. Create-A-Show Create-A-Show allows you to create customized lectures by exporting Clinical Atlas plates to this application, where you can modify the graphics and text. You can also import your own graphics to personalize your presentation. How to Make the Most of This Program 4
  14. 14. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 5 MEDICAL PROFESSIONALS Quick Reference The Interactive Atlas of Clinical Anatomy is an up-to-date reference for practicing professionals who may want to refresh their knowledge from time to time. Staff Training The same features that make the program ideal for teaching students in the classroom—for example, the side-by-side “compare” screens showing normal anatomy and medical imaging views or clinical procedures—make this program useful for staff training and for patient education. Patient Education Patient education is an important—and time-consuming—part of any clinical practice. The Clinical Atlas screens can be printed out with or without labels and handed to patients for their reference. Practitioners find this a useful and timesaving program feature. Moreover, they can use the List Manager function to prepare their own personal collections of images for use with the various types of patients they see in their practice. How to Make the Most of This Program 5
  15. 15. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 6 WHAT THIS PROGRAM CONTAINS VISUAL CONTENT Visual Index Thumbnail-size pictures of all the images in the program, organized by the type of plate (see next items). Go directly to a plate by double-click- ing its thumbnail picture. Atlas Plates All 525 plates (translating into 930 screens) of normal anatomy from the Interactive Atlas of Human Anatomy. Cross Sections 183 cross-sectional illustrations. Correlations 532 plates, derived from The Ciba Collection of Medical Illustrations and Clinical Symposia, plus a variety of radiographic images. Each plate “correlates” with one or more Atlas plates (or, in some cases, anoth- er correlation), and can be shown side-by-side with it on a “compare screen.” Each correlate plate has a brief explanatory text. Seven types of correlations: Clinical Imaging* Procedural Anatomical Functional Developmental Histological *Imaging correlations are also grouped as a separate collection called Imaging (see next item). Imaging 222 radiographs, CT scans, MRIs, 3-D CTs, and other types of diagnostic images; organized by body region. Brief text for each. Visible Human 21 interactive movies based on the National Library of Medicine’s Visual Human™ data set. See sections of male body and the female pelvis* in axial, sagittal, and coronal planes. For key frames of the Visible Male, overlay a correlating CT scan and cross-sectional illustration. *When Version 1.0 of the Clinical Atlas was being prepared, only the male portion of the database was available. Now, although the female database is complete, the space limitations of the CD-ROM do not permit us to include both sets of complete data. We have, therefore, retained the complete set of images for the male, which contains all the essential normal human data, and completed the human database with the female pelvis and perineum. What This Program Contains 6
  16. 16. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 7 NAVIGATIONAL FEATURES These icons give you access to all the visual content in the program. Regions Find all of the plates in the program pertaining to a body region. Systems Find all of the plates in the program pertaining to an organ system. Search Find plate titles or labels containing the term you input. EDUCATIONAL FEATURES These buttons allow you to personalize the contents of the program to fulfill your educational needs as a student, instructor, or medical professional. List Manager Create your own list of plates. Save them, and use them for study guides, tests, or presentations. Your Personal List File can contain many lists. The Active List is the list you are currently working with. Study Guide Make a group of plates into a study guide by displaying only certain points and labels. Attach a Guide Note (an audio or text note pertaining to that plate). Test Ⅲ Take a Practice Test on the plate you are viewing. Ⅲ Create a Custom Exam—either “Name Structures” or “Locate Structures.” Ⅲ Create a Written Questions Exam. Create-A-Show Export plates from the Clinical Atlas into this application and alter them to suit your purpose (change fields, lines, graphics). Print Print out anatomical plates with or without labels and points, in color or black and white. What This Program Contains 7
  17. 17. ACL guide WORKING.hpc copy 4/23/98 11:47 AM Page 8 Exam Record Utility Load one or more exam records into the Exam Record Utility, which provides you with the ability to calculate the class average and range for a given test, review the test records for individual students, and print a grade list. TUTORIALS To better understand how to use this program, watch step-by-step instructional movies for these features: Getting Started List Manager Study Guide Tests Create-A-Show STUDY PREPARATION BUTTONS These buttons permit you to load files that have been previously saved to a disk. PLATE CONTROL BUTTONS These buttons appear on the side of the plate screen and allow you to fully explore the plate, its correlations, and lists of plates you have created. Plate Navigation Move through the plates sequentially, and see a list of the plates and compare screens you viewed in the current session. What This Program Contains 8
  18. 18. ACL guide WORKING.hpc copy 4/23/98 11:48 AM Page 9 Labels, Points See labels and points (or hide them) for a plate on the screen. Select List Work with any lists in the file you have loaded. See the name of the Active List and the items it contains. Study Plates Work with the Study Guide plates. Read text notes (or listen to audio notes) attached to a study plate. A check mark in the Guide Note box means there is an audio or text note attached to the study plate. Correlates See correlate anatomical and clinical images on a side-by-side (compare) screen, or access correlate texts. An arrow in the box means this plate has correlate images. Plate Notes Create and read text notes attached to a plate. A check mark in the Plate Note box means there is a note attached to this plate. Use this button also to create general notes on your notepad. Magnify Activate a 2x magnification window. Help Use the on-line Help for features and functionality of the program. Stop Exit the program. What This Program Contains 9
  19. 19. ACL guide WORKING.hpc copy 4/23/98 11:48 AM Page 10 LICENSE AGREEMENT SINGLE USER/SINGLE COMPUTER LICENSE AGREEMENT FOR INTERACTIVE ATLAS OF CLINICAL ANATOMY Please read this license carefully before using the software. By using this software, the licensee agrees to be bound by the terms of this license. If the licensee does not agree to the terms of this license, licensee should return the unused software promptly to DxR Development Group, Inc., 150 E. Pleasant Hill Road, Carbondale, IL 62901 (800-453-8040) or Novartis Pharmaceuticals Corpo- ration, Novartis Medical Education, 556 Morris Avenue, Summit, NJ 07901 (800- 631-1181). 1. LICENSE. Interactive Atlas of Clinical Anatomy (hereafter “Software”) software program and related documentation accompanying this License, whether on disk, in read-only memory, or on any other media, are licensed to you (hereafter “Licensee”) by Novartis Pharmaceuticals Corporation, Novartis Medical Educa- tion (hereafter “Novartis”) and DxR Development Group, Inc. (hereafter “DxR”). The Licensee may use the Software, but Novartis and DxR retain title to the Software and related documentation, which are protected by United States and international copyright laws and international trade provisions. The Licensee must treat this Software like any other copyrighted material. Novartis and DxR grant the Licensee a nonexclusive license to use one copy of the Software on a single computer, and to make one copy of the Software for archival purposes, or copy the Software onto the hard drive of the Licensee’s computer and retain the original for archival purposes. The Licensee may not make copies of the Soft- ware for use on any other computer or permit any other person to use the Soft- ware. Licensee may not use this Software in whole or in part for any com- mercial enterprise. 2. RESTRICTIONS. The Software contains copyrighted material, trade secrets, and other proprietary information, and, in order to protect them, the Licensee agrees not to disassemble or otherwise reduce the Software to a human- perceivable form. The Licensee agrees not to modify, rent, lease, loan, distribute, or create derivative works based upon the Software in whole or in part. The Licensee shall take reasonable precautions to prevent any unauthorized use or dissemination of the Software. Rights assigned the Licensee in this agreement are not transferable. Licensee may not use the Software in whole or in part for any commercial applications. 3. TERMINATION. This License is effective until terminated. The Licensee may terminate this License at any time by returning the original Software and related documentation. Copies of the Software shall either be returned to Novartis or License Agreement 10
  20. 20. ACL guide WORKING.hpc copy 4/23/98 11:48 AM Page 11 DxR, or destroyed by Licensee. If destroyed, the Licensee shall supply written verification of such destruction to DxR Development Group, Inc., 150 E. Pleasant Hill Road, Carbondale, IL 62901 (800-453-8040) or Novartis Pharmaceuticals Corporation, Novartis Medical Education, 556 Morris Avenue, Summit, NJ 07901 (800-631-1181). This License will terminate immediately without notice from Novartis or DxR if the Licensee fails to comply with any provision of this License. 4. DISCLAIMER OF WARRANTY ON SOFTWARE. The Licensee expressly acknowledges and agrees that use of the Software is at its sole risk. The Soft- ware and related documentation are provided “AS IS” and without warranty of any kind, and Novartis and DxR expressly disclaim all warranties, expressed or implied, including, but not limited to, the implied warranties of fitness for a partic- ular purpose. Novartis/DxR do not warrant that the functions contained in the Software will meet the Licensee’s requirements, or that the operation of the Soft- ware will be uninterrupted or error free, or that defects in the Software will be cor- rected. Furthermore, Novartis/DxR do not warrant or make any representations regarding the use or the results of the use of the Software or related documenta- tion in terms of their correctness, accuracy, reliability, or otherwise. No oral or written information or advice given by Novartis/DxR or its authorized representa- tive shall create a warranty or in any way increase the scope of this warranty. 5. LIMITATION OF LIABILITY. Under no circumstances, including negligence, shall Novartis/DxR be liable for any incidental, special, or consequential dam- ages that result from the use or inability to use the Software or related documen- tation, even if Novartis/DxR or its authorized representative has been advised of the possibility of such damages. 6. SEVERABILITY. If for any reason a court of competent jurisdiction finds any provision of this License, or portion thereof, to be unenforceable, that provision of the License shall be enforced to the maximum extent permissible so as to effect the intent of the parties, and the remainder of this License shall continue in full force and effect. 7. COMPLETE AGREEMENT. This License constitutes the entire agreement between the parties with respect to the use of the Software and related docu- mentation, and supersedes all prior or contemporaneous understandings or agreements, written or oral, regarding such subject matter. No amendment to or modification of this License will be binding unless in writing and signed by a duly authorized representative of Novartis and DxR. License Agreement 11
  21. 21. ACL guide WORKING.hpc copy 4/23/98 11:48 AM Page 12 INSTALLING AND RUNNING THE PROGRAM If you need assistance installing or running the Clinical Atlas, please call DxR Development Group, Inc., at (800) 453-8040 or (618) 453-1140 between 9 A.M. and 5 P.M. Central Time, Monday through Friday. You may also send e-mail to WINDOWSTM To install the program, please follow these steps: 1. Insert the CD into the tray and close the tray door. 2. To install the program, choose Run from the Program Manager File menu (Windows 3.1x) or choose Run from the Start menu on the Task Bar (Windows 95). Type D:SETUP.EXE (Where D is the letter of your CD-ROM drive), and click OK. 3. A Program Manager Group for the Clinical Atlas will be installed. Double-click the Clinical Atlas icon to start the program. Note: The Clinical Atlas software must be installed and the CD must be in the CD tray to use the Create-A-Show. MACINTOSH® To install the program, please follow these steps: 1. Insert the CD into the tray and close the tray door. 2. To begin the program, double-click the Clinical Atlas icon. Note: The Clinical Atlas CD must be in the CD tray to use the Create-A-Show. Installing and Running the Program 12
  22. 22. ACL guide WORKING.hpc copy 4/23/98 11:48 AM Page 13 Printed in USA 12M697HPC