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Engineering: a key knowledge for boosting the competitiveness of biotechnology-based companies
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Engineering: a key knowledge for boosting the competitiveness of biotechnology-based companies



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  • 1. Engineering: a key knowledge for boosting thecompetitiveness of biotechnology-based companies:
  • 2. PRODINTEC – Introduction Date created: October 2004. Formed as a private non-profit. Board composed of private companies in Asturias, University and Government of the Principality of Asturias. Location: Science and Technology Park of Gijón (Asturias) Delegation in Madrid: Science and Technology Park of Madrid, PC 28760 Madrid TarjetEnchancing competitiveness of enterprises through the application of technological advances boththeir products and their manufacturingprocesses and management.
  • 3. The bridge between research & innovation Tarjet: the market
  • 4. Research Spain: - 9º worldwide position - 3,3% scientific production Fuente: SCImago, Scopus, ISI, Thomson Reuters
  • 5. Innovation39º worldwide position36º in EuropeFuente: The Global Competitiveness Report 2011–2012
  • 6. What is the reason? Who would go? What steps do I follow? How I can have functional prototype pre-series or commercial? How I can industrialize my idea?
  • 7. Why innovate in Biotechnology?• Improving the quality of life of individuals and societyTechnologies, techniques, tools, equipment, devices, medical and surgical procedures, information systems, health programs, organization forms for the prevention, diagnosis, treatment and rehabilitation. DEMAND AS THE ECONOMY AS TECHNOLOGY SOCIETY REQUIRED ALLOWS HEALTH
  • 8. Value chain Law firm 1. Detect potentially interested +• From the research to the market 2. Contact potential applicants 3. Negotiations and drafting transfer agreementI Return l Return Mn i av ED CD DD c PE P M re e kn n e Estrategic Conceptual Detailed Product Production Merchandisingti Definition Design design s Engeneering to e Producto Concept Specification, Technical Manufacturingn definition generation assembly Solution and Process definition drawings, Manufacturing prototypes drawingsI VIABILITY,d INTELECTUAL PROPERTY RIGHTSea - Companie - Research group Licensee + - Spin Off - Hospital + - Tech Based companies
  • 9. Objetives• Provide technical support from invention / patent to the market.• Provide technological muscle for design and manufacturing process to provide "value" to the contact process, selection and negotiation with a licensee end. - "Convince" the licensee of the technical end. - Checking the operating principle and development prototypes to assist in this process.• Cover the gap between the licensee and technical office, production and commercialization. - Provide tools that facilitate the industrialization and placing on the market
  • 10. ApplicationsIVD: Kits and diagnostic devices, sensors, microfluidics, etc.. Detection and measurement of biochemical and biological parameters, identification of toxicsubstances, drugs, etc..Biomedical engineering:Surgical tools, implants, custom designs, accessories, new features, etc..Food Biotechnology: Systems for use in situ detection of contaminants or pollutants detection of biological agents.Biosensors / Equipment / Instruments: Prototypes (first series, enclosures, laboratory equipment, cells, interfaces, developinganalytical instrumentation, robotics).Security and Defence: Devices for the detection of biochemical weapons, explosives, and drugs, etc..Biocatalysis/ Bioreactors Scale-up, Industrialization, bioreactors design and manufacturing, etc.
  • 11. Predica Model
  • 13. Future
  • 14. Biomedical Models Patient/ModelGeneration 3D Modeling and CAD Choice of technology and manufacturing Rapid production of 3D models at low cost. Time reduction interventions, better communication and decision making, precise adjustment of implant training. Applications
  • 15. Tools, Implants, orthopedic, …Need, implementation,//Know how/IdeaGeneration 3D Modeling and CAD Choice of technology and manufacturing
  • 16. Medical Devices, PoC, Biosensors, … ProtocoloMechanical design and generation of CAD +Electrical and electronic design of the device,reading system, control, Choice of technology and Test manufacturing Product
  • 17. Equipment, Instruments, Machinery…Need / New functionality / Machinery ad hoc Mechanical design and simulation +3D modeling and design of components + Electrical and electronic design of the device, Choice of technology and Test Product reading system, control, manufacturing ...
  • 18. Case StudiesComplete redesign and manufacture a set of instruments for bone surgery highlyinnovative
  • 19. Case StudiesDesign and manufacture of a diagnostic device and electrochemical detection.Objective: miniaturization, microfluidics [capillary electrophoresis chips], portable,communication USD / Bluetooth.
  • 20. Case StudiesInstrumentatión Rakes Instrumentation rakes or combs. - Pressure and temperature probes - To manufacture complex parts - Withstands high temperatures Manufacture: - SLS part made ​by Inconel - Polished finish - Manufactured in one piece
  • 21. Equipment EOSINT M-270 EOSINT M-280 EOS FORMIGA P-100 EOS P-395Machine Fabrication of direct metal laser sintering: Manufacturing Machine direct laser sintering of plastics:Able to work with steels, stainless steels, cobalt chrome, brass, Able to work with plastics, nylons, etc.. Layered fabricationtitanium, etc.. Layered fabrication technology that can produce technology that can produce finished parts from 3D CAD andfinished parts from 3D CAD and metal powders. Typical polymeric materials. Typical applications: complex geometric parts,applications: complex geometric parts, tools, molds with machinery parts and small series without making molds, etc..conformal channels, custom inserts, prosthetic devices, etc.. Aplications
  • 22. Equipment EDEN 330 multijet OBJECT CONNEX 500Rapid Prototyping: Rapid Prototyping:Prototyping PolyJet technology by injection consisting of Prototyping PolyJet technology by injection consisting ofphotoresists and later cured by ultraviolet light. Direct photoresists (possibility of use of 2 different polymer resinsconnection to CAD and engineering software reverse simultaneously) and later cured by ultraviolet light. DirectPRODINTEC connection to CAD and engineering software reverse PRODINTEC Aplications Industries Materials Case Studies
  • 23. Equipment MCP 4/04 ZCORP Z510Vacuum Casting: Rapid prototyping, prototyping based on material by dustMaking pre-series in plastic and metal from a physical part. and its suburbs by colored liquid. Infiltration finish with cyanoacrylate (getting very hard piece) or epoxy resin (flexible piece collection). Aplications Industries Case Studies
  • 24. Equipment Wittmann-Battenfeld Deckel Maho KERN Evo Microsystem50Milling Microinjection machine, Micromilling machining by chipfully equipped robotic cell for automated that allows the injection of removal in high speed, to obtainmanufacturing via the machining of large plastic parts, metal and ceramic absolute accuracies in the vicinity ofparts (measuring up to several metres), with micro geometries, handling, one micron. Applications in the fieldaccuracies of tenths of a millimetre and in quality control and automatic of micro and nanotechnologiesmaterials such as resin, wood, expanded blister packaging clean room.polystyrene, etc.We also have a high-speed 5-axis milling Microinjection Micromillingmachine that allows us to produce very highprecision parts with complex geometries inany material
  • 25. Equipment CemLab MecathronicsElectromagnetic Compatibility Laboratory: Performing Mechatronics: Design and development of electronic circuits.compatibility tests or external devices developed at the Center Instrumentation, control and measurement. Processfor CE marking automation. PCB prototyping equipment.
  • 26. In short…1.- Full development of device from companies know how to prototype orfunctional first series.2.- Manufacturing direct piece further tools and functionalities in teams.3.- Design and manufacture of machinery and devices for analysis, sensors andbiosensors for diagnosis.4.- Design and manufacture of interfaces, cells supports analysis kits ...5.- Manufacture of medical model to patient.6.- Design and manufacture of devices for detection and sampling.7.- Unlocking the design constraints of traditional manufacturing processes.8.- Access to new market niches.9.- Reduce costs in small series.10.- "Mass customization", batch unit, as ...EXAMPLES OF APPLICATIONmedical implants, orthopedic products, support structures, surgical tools,diagnostic devices, interfaces, flow cells, envelopes, microarrays ....
  • 27. International Presence Technology Platforms International Projets Rapid Manufacturing European Plaftorm EKA Prodintec manager is a board member European Technology Platform Manufuture Platform manufacturing INTERREG technologies. In his likeness created the regional platform PRODINTEC ESTIIC RFID4SME Manufacturias NANO4M MINAM +NANOfutures Frame Program Micro and nanofabrication FP6: Syntex platforms Prodintec Manager is a board FP7: Light-Rolls (coordinador) member FP7: NANOfutures (CSA)Prodintec also a member of: Iberian Red RICAI Center for FP7: CIS3D (NMP)Innovation, Red PYMERA, Europe InterCluster, HISPAROB SpanishTechnology Platform on Robotics and Technical IDESA Consortia
  • 28. Our Team and facilities
  • 29. PRODINTECCentro tecnológico para el diseño y la producción industrial EDIFICIO CENTROS TECNOLÓGICOS PARQUE CIENTÍFICO Y TECNOLÓGICO 33203 GIJÓN. ASTURIAS T +34 984 390 060 F +34 984 390 061 DELEGACION EN MADRID T +31 667 728 947