proposal

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proposal

  1. 1. RISE program Research proposal Francisco J Fuster
  2. 2. <ul><li>While using antiperspirant deodorant: </li></ul><ul><li>-No smell </li></ul><ul><li>-No sweat </li></ul><ul><li>How does the antiperspirant work? </li></ul><ul><li>-It clogs sweat ducts with aluminum compounds. </li></ul>
  3. 3. <ul><li>Excessive aluminum concentrations cause: </li></ul><ul><li>-estrogen like effects that stimulate breast cancer cell growth. </li></ul><ul><li>-cell membranes more fluid. </li></ul>
  4. 4. <ul><li>Sweat Regulates: </li></ul><ul><li>Body Temperature </li></ul><ul><li>=can be affected by heat absorption. </li></ul><ul><li>-so darker races sweat more due to light attraction by pigmentation. </li></ul>
  5. 5. <ul><li>High aluminum concentrations: </li></ul><ul><li>-Make cell membranes more fluid. Like the disease Alzheimer’s which is why this is linked to the disease. </li></ul><ul><li>Experiments with aluminum in blood: </li></ul><ul><li>-prove that it causes fluidity in cell membrane </li></ul>
  6. 6. <ul><li>A safe consumption of aluminum: </li></ul><ul><li>- <5 μ g/kg/day. </li></ul><ul><li>Most of it is removed by the kidneys. </li></ul><ul><li>Any higher consumption can lead to many other symptons. </li></ul>
  7. 7. <ul><li>Sweat Toxins: </li></ul><ul><li>Dermcidin </li></ul><ul><li>=Regulates the skin flora, functions as a natural antibiotic. </li></ul><ul><li>Any substance absorbed needs to be released. </li></ul><ul><li>-Ex. Nicotine from cigarettes. </li></ul>
  8. 8. <ul><li>To find and avoid a probable cause of breast cancer. </li></ul><ul><li>This may cause breast cancer because: </li></ul><ul><li>-Toxins from sweat mutate lymphatic nodules from the nearby area. </li></ul>
  9. 9. <ul><ul><li>Do antiperspirant deodorants stimulate the growth of breast cancer cells? </li></ul></ul><ul><ul><li>Do they cause harm to any other part of the human body? </li></ul></ul><ul><ul><li>What is the quantity of aluminum being absorbed by the users? </li></ul></ul>
  10. 10. <ul><li>Antiperspirant deodorant causes: </li></ul><ul><li>-Breast cancer </li></ul><ul><li>-trap toxins in the body </li></ul><ul><li>-Aluminum concentrations can further harm the human body. </li></ul><ul><li>-Is linked to Alzheimer’s disease. </li></ul>
  11. 11. <ul><li>The more a person sweats while using the antiperspirant deodorant the more probability for additional health problems. </li></ul>
  12. 12. <ul><li>Primarily: </li></ul><ul><li>-Survey a population of 300 people. </li></ul><ul><li>=Find out those who have used antiperspirant deodorant for more than a year. </li></ul><ul><li>This would take convincing those who use the antiperspirant deodorant to volunteer for an serum aluminum test which indicates the level of aluminum in blood. </li></ul>
  13. 13. <ul><li>Volunteers will be notified of their rights. </li></ul><ul><li>At least 50 control and 50 experimental volunteers will be needed. </li></ul><ul><li>Ask for history of cancer in family. </li></ul><ul><li>Exercise is questioned. </li></ul><ul><li>Race. </li></ul><ul><li>Compare the levels of aluminum between control and experimental, the normal level of aluminum in blood, race and amount of exercise. </li></ul>
  14. 14. <ul><li>www.nih.gov </li></ul><ul><li>Jones J. Can rumors cause cancer? Journal of the National Cancer Institute 2000; 92(18):1469–1471. </li></ul><ul><li>Darbre PD. Underarm cosmetics and breast cancer. Journal of Applied Toxicology 2003; 23(2):89–95. </li></ul><ul><li>Darbre PD. Aluminium, antiperspirants and breast cancer. Journal of Inorganic Biochemistry 2005; 99(9):1912–1919. </li></ul><ul><li>Harvey PW, Everett DJ. Significance of the detection of esters of p-hydroxybenzoic acid (parabens) in human breast tumours. Journal of Applied Toxicology 2004; 24(1):1–4. </li></ul>
  15. 15. <ul><li>Darbre PD, Aljarrah A, Miller WR, et al. Concentrations of parabens in human breast tumours. Journal of Applied Toxicology 2004; 24(1):5–13. </li></ul><ul><li>Mirick DK, Davis S, Thomas DB. Antiperspirant use and the risk of breast cancer. Journal of the National Cancer Institute 2002; 94(20):1578–1580. </li></ul><ul><li>McGrath KG. An earlier age of breast cancer diagnosis related to more frequent use of antiperspirants/deodorants and underarm shaving. European Journal of Cancer 2003; 12(6):479–485. </li></ul><ul><li>Fakri S, Al-Azzawi A, Al-Tawil N. Antiperspirant use as a risk factor for breast cancer in Iraq. Eastern Mediterranean Health Journal 2006; 12(3-4):478–482. </li></ul>
  16. 16. <ul><li>Susan J. van Rensburg 1 , Machteld E. Carstens 1 , Felix C. V. Potocnik 2 , Abraham K. Aucamp 3 , Joshua J. F. Taljaard 1 and Klaus R. Koch 4 Neurochemical Research a journal of Springer Netherlands 2005 pgs 825-829 </li></ul><ul><li>Immune Mechanisms Against Extracellular Pathogens Nature Encyclopaedia of Life Sciences </li></ul><ul><li>www.googlescholar.com </li></ul>
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