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Corticosteroid complications
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Corticosteroid complications

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  • 1. Important complications of corticosteroidsGlucocorticoid effectsavascular necrosis of the femoral and humeral headdermatological effects (eg skin atrophy, purpura and ecchymoses, striae, hirsutism)gastrointestinal effects (eg dyspepsia, peptic ulceration, gastrointestinal bleeding)growth retardation (monitor in children)immunosuppression, risk of infectionsmetabolic effects (eg hyperglycaemia, hypertriglyceridaemia)myopathyocular effects, particularly increased intraocular pressure and cataractsosteoporosisadrenal suppression (see Dosing: general information)psychological and sleep disturbances (eg euphoria, depression, paranoid psychosis)weight gain and redistribution of fatMineralocorticoid effectshypertensionhypokalaemic alkalosissodium-retaining effects (oedema)Most of the adverse effects relate to long-term treatment and do not preclude short-termuse.