On October 23rd, 2014, we updated our
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Clinical guideline for management of suspected CA-MRSA infections (15 March 2007)
Most CA-MRSA isolates in HKSAR are susceptible to:
Out-patient oral therapy available for uncomplicated CA-MRSA skin and soft tissue infection
Methicillin resistant Staphylococcus aureus (MRSA) Antimicrobials for outpatient therapy of uncomplicated skin and soft tissue infections (Clinical guideline for management of suspected CA-MRSA infections,15 March 2007) Agent Potential advantage Precautions Usual adult dose (oral) Cotrimoxazole Oral Not for patient with sulfa allergy / G6PD 960mg bd Doxycycline High skin concentration Not for children <12 yo or pregnant women 200mg once, then 100mg bd Minocycline As above As above 100mg bd Clindamycin Inhibit toxin production Inducible resistance if erythromycin resistant 300-450mg tds Moxifloxacin Oral Resistance may develop during therapy 400mg qd