Anatomy And Connections Of Prefrontal Cortex
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Anatomy And Connections Of Prefrontal Cortex

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Anatomy And Connections Of Prefrontal Cortex Anatomy And Connections Of Prefrontal Cortex Presentation Transcript

  • In the name of God Basic neurosciences with clinical applications
  • Anatomy and connections of prefrontal cortex
    • Lateral prefrontal cortex : with lots of reciprocal areas is well suited to regulate behavior and control of response to environmental stimuli
    • Orbitomedial prefrontal cortex : via its reciprocal neocortical and limbic connections ,is suited to integrate information about emotion and memory related to environmental stimuli
  • Lateral prefrontal cortex
    • It is divided in to 3 parts:
    • The dorso lateral prefrontal cortex:areas 9 &46
    • Ventrolateral prefrontal cortex:44 & 45 & 47 & 12
    • Frontopolar cortex: including the superior polar(areas 9 & 10) and inferior polar(10,47/12&14)
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  • The connections of lateral prefrontal cortex
    • The main connections are with paralimbic areas,particular the cingulate gyrus .
    • This connections myelinate late during cerebral development.
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  • dorsolateral prefrontal cortex Spatial attention
    • Superior longitudinal fasciculus connects caudal portion of inferior parietal lobule and parietooccipital region and dosral lateral prefrontal cortex
    • This connection involve in visual and oculomotor aspects of spatial attention
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  • Ventrolateral prefrontal cortex actin imitation, gestural communication ,monitoring orofacial & hand action
    • Inputs from anterior portion of inferior parietal lobe including supramarginal gyrus and adjacent parietal opercular region , terminate in VLTPC & frontal operculum(44) & ventral premotor area?
    • This Provide high order somatosensory input for action imitation,gestural communication,orofacial and hand action
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  • Ventrolateral prefrontal cortex visual object identification
    • Occipitotemporal visual association areas terminate primarily in inferior temporal cortex and adjacent parahippocampal region via inferior longitudinal fasciculus and then to VLPFC
    • This system transmits highly processed visual information necessary for object identification.
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  • ventral prefrontal cortex auditory spatial info/object recognition
    • Posterior portion of Superior temporal gyrus projects to area 8 via arcuate fasciculus, information for
    • auditory spatial information
    • Midportion of superior temporal gyrus projects to area 45 via the extreme capsule ,provides info for
    • auditory object recognition
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  • ventral prefrontal cortex of left hemisphere recieve distinct inputs for speech production
    • Thus,the VPFC involved in speech production receive distinct sensory inputs
    • Area 44: somatosensory inputs from the supramarginal gyrus
    • Area 45:auditory info from midsuperior temporal cortex
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