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Agathe Raynaud-Simon Service de Gériatrie, H ôpital Bichat APHP, Paris Faculté de Médecine Denis Diderot, Paris 7 Laboratoire de Biologie de la Nutrition, EA4466, Faculté de Pharmacie, Paris 5 Evaluation  of  malnutrition
Malnutrition
Malnutrition and mortality ,[object Object],[object Object],[object Object],[object Object],[object Object]
Assessment of malnutrition ,[object Object],[object Object],[object Object]
Risk factors for malnutrition Cancer Cardiac Respiratory Liver Renal Chronic infections Chronic inflammation Malabsorption Maldigestion Failure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Psychiatric disorders Disability Swallowing disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Neurologic Restrictive diets Mouth and teeth ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Drugs Acute conditions, Worsening of a chronic condition Psychologic, social and environement
Risk factors for malnutrition Cancer Cardiac Respiratory Liver Renal Chronic infections Chronic inflammation Malabsorption Maldigestion Failure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Psychiatric disorders Disability Swallowing disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Neurologic Restrictive diets Mouth and teeth ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Drugs Acute conditions, Worsening of a chronic condition Psychologic, social and environement
Evaluation of food intake
Nutritional parameters and life-threatening complications in geriatric patients   Sullivan DH et al, J Gen Intern Med  2002; 17: 923 - 932 4,0% ≥  22 kg/m ² 0,008 15,4% BMI   < 22 kg/m ² 4,6% ≥  18 mg/dL   0,046 10,5% Transthyretin  < 18 mg/dL 5,3% ≥  30 g/L 0,018 13,3% Albumin   < 30 g/L  4,5% no <0,001 19% Weight loss   > 5 %   yes 3,2% > 323 mm 2,4% 286 – 323 mm <0,001 13,8% MAC  < 286 mm P-Wert Complication rate Parameter
Malnutrition « Marasmus » Progressiv weight loss Protein and energy deficiency Muscle and fat loss Normal albuminemia No edema « Kwashiorkor » Rapid weight loss Protein deficiency Muscle mass loss Hypoalbuminemia Edema
Volkert D et al. Aktuel Ernaehr Med 2004; 29: 190-197 40 % 82    5 215 acute care, mixt Volkert (1992) 33 % 79    6 110 rehabilitation Sullivan (1994) 22 % 79    6 302 acute care, mixt Incalzi (1996) < 22 52 % 80    7 42 hip fracture Ponzer (1999) 35 % 83    4 99 acute care, mixt Dormenval (1999) 8 % > 70 116 ICU (respirator) Dardaine (2001)  < 21 36 % 81    1 337 acute care, mixt Flodin (2000)    20 36 % 80    7 42 hip fracture Ponzer (1999) 31 % 78    9 201 stroke Gariballa (1998) 26 % 62 95 Parkinson Markus (1993) 21 % 82    5 215 acute care, mixt Volkert (1992) < 20 17 %    65 127 acute care, mixt DaCunha (2001) < 18,5 31 % 80    9 119 hip fracture Maffuli (1999) 9 % 82    5 215 acute care, mixt Volkert (1992) < 18 11 % 80    9 119 hip fracture Maffuli (1999) < 16 prevalence age n patients author BMI
Malnutrition criteria ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mini- MNA - risk factors - appetite - nutritional criteria  NEW ! Kaiser, JNHA 2009
[object Object],[object Object],[object Object],Geriatric  Nutritional Risk Index Bouillanne et al, Am J Clin Nut, 2005
Assessment  of nutritional status Body storage Weight, BMI How much fat? How much muscle? Metabolic homeostasis Albuminemia? Glycemia? Ca? P? …

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Raynaud

  • 1. Agathe Raynaud-Simon Service de Gériatrie, H ôpital Bichat APHP, Paris Faculté de Médecine Denis Diderot, Paris 7 Laboratoire de Biologie de la Nutrition, EA4466, Faculté de Pharmacie, Paris 5 Evaluation of malnutrition
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  • 8. Nutritional parameters and life-threatening complications in geriatric patients Sullivan DH et al, J Gen Intern Med 2002; 17: 923 - 932 4,0% ≥ 22 kg/m ² 0,008 15,4% BMI < 22 kg/m ² 4,6% ≥ 18 mg/dL 0,046 10,5% Transthyretin < 18 mg/dL 5,3% ≥ 30 g/L 0,018 13,3% Albumin < 30 g/L 4,5% no <0,001 19% Weight loss > 5 % yes 3,2% > 323 mm 2,4% 286 – 323 mm <0,001 13,8% MAC < 286 mm P-Wert Complication rate Parameter
  • 9. Malnutrition « Marasmus » Progressiv weight loss Protein and energy deficiency Muscle and fat loss Normal albuminemia No edema « Kwashiorkor » Rapid weight loss Protein deficiency Muscle mass loss Hypoalbuminemia Edema
  • 10. Volkert D et al. Aktuel Ernaehr Med 2004; 29: 190-197 40 % 82  5 215 acute care, mixt Volkert (1992) 33 % 79  6 110 rehabilitation Sullivan (1994) 22 % 79  6 302 acute care, mixt Incalzi (1996) < 22 52 % 80  7 42 hip fracture Ponzer (1999) 35 % 83  4 99 acute care, mixt Dormenval (1999) 8 % > 70 116 ICU (respirator) Dardaine (2001) < 21 36 % 81  1 337 acute care, mixt Flodin (2000)  20 36 % 80  7 42 hip fracture Ponzer (1999) 31 % 78  9 201 stroke Gariballa (1998) 26 % 62 95 Parkinson Markus (1993) 21 % 82  5 215 acute care, mixt Volkert (1992) < 20 17 %  65 127 acute care, mixt DaCunha (2001) < 18,5 31 % 80  9 119 hip fracture Maffuli (1999) 9 % 82  5 215 acute care, mixt Volkert (1992) < 18 11 % 80  9 119 hip fracture Maffuli (1999) < 16 prevalence age n patients author BMI
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  • 12. Mini- MNA - risk factors - appetite - nutritional criteria NEW ! Kaiser, JNHA 2009
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  • 14. Assessment of nutritional status Body storage Weight, BMI How much fat? How much muscle? Metabolic homeostasis Albuminemia? Glycemia? Ca? P? …

Editor's Notes

  1. The prevalence rates in the different studies therefore differs widely as a consequence of the different parameters used for the diagnosis of malnutrition . For example these are some the data for the BMI. The rates differ according to different cut off values. Look at the data provided by Volkert and collegues. The chose a population of patients from acute care. The prevalence if they use a cut off value of 18 or 22.