www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop de Capacitação emEscrita CientíficaMódulo 1Pr...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop OutlineModulo 1: O Gênero LiterárioSeções de ...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMódulo 1O Gênero LiterárioEstrutura 1
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhy?, What?, When?....
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhy to Publish??Publication is one of the most importa...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhat do we Publish?Scientists Publish Ideas !!
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhen to Publish?When the initialquestion/problem/hypot...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brScientific Method /Hypothesis testingWhen to Publish?
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br-Distinct time scales for distinct areas;-Depends on t...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPublishing IdeasIdeasImplementation of the ResearchRes...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br1.General Considerations
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brLesson ZeroScientific writing as a “new” LiteraryGenre
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIn the very beginning…. Informal Letters exchanged by...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAudienceWho will read your paper?Highly technical jour...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brClarity and ConcisionReport your results clearlyUse as...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brReferencesAll information or ideas must be referenced!...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br2.Sections of a Regular Paper
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brTypes of Scientific PublicationsThesisEncyclopediasRes...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brGeneralSpecificAdapted from: Hill et al., Teaching ESL...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brTitle, Authors and AffiliationsA good Title describes ...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExample 1: A paper reporting on the influence of themo...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brTitle 2: The influence of the MW on the Mechanicalprop...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brOK!! The author describes the most important resultsho...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWho are the authors of a paper?Title, Authors and Affi...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brGuidelines to define authorship:All authors must be ab...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAuthors Names Sequence:First NameThe researcher who di...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAffiliations usually include the following information...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAbstract
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContextualizationGapPurposeMethodologyResultsConclusio...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brSelf-assembly of components larger than molecules into...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br1) Context: Self-assembly of components larger than mo...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIntroduction
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIntroductionContextualizationSumarizing PreviousResear...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMethodology
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMethodologyMaterialsWhat materials were employed?Where...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brResults and Discussion
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brResultsIntroduction(purpose)Results and Discussion(Key...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brConclusion
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIn contrast to the Introduction, theconclusions sectio...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brKey findingsInterpretation of main ResultsContribution...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brReferencesAll information or ideas must be referenced!...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExamples―….However, recent reports have been made on t...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExamples―….The layer-by-layer (LbL) technique has been...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brA Suggested Sequence….Results and DiscussionsConclusio...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brBegin writing in EnglishTake your notes in EnglishFina...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPlagiarismYou may cite others’ words, data, etc. using...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brhttp://www.fapesp.br/boaspraticas/codigo_fapesp0911.pd...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPlagiarism
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br-Introduction to Journal-Style Scientific Writing:http...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brValtencir Zucolottozuco@ifsc.usp.brwww.nanomedicina.co...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop de Capacitação emEscrita CientíficaMódulo 2Pr...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop OutlineModulo 1: O Gênero LiterárioSeções de ...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMódulo 2Estrutura 1: Abstract
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brGeneralSpecificOrganization of a paperGeneralAdapted f...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAbstract
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAbstractAn abstract summarizes the major aspects of th...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brInformativeContains all therelevant information ofthe ...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brStyle- Past Tense (whenever possible);- Active voice p...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContextualizationGapPurposeMethodologyResultsConclusio...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brJ Pharm Pharmaceut Sci 8(2):162-178, 2005Abstract
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExamples from the Literature
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brSelf-assembly of components larger than molecules into...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br1) Context: Self-assembly of components larger than mo...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brBioinert polyelectrolyte multilayers comprised of poly...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContext??Gap??Purpose?: Bioinert polyelectrolyte multi...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brDendrimers are branched, synthetic polymers with layer...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContext: Dendrimers are branched, synthetic polymers w...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 1Metallophthalocyanines (MPcs) are conjugated ...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 2Vibrational energy flow into reactants, and o...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 3Polymer nanoparticles are widely used as a hi...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 4Currently, mass spectrometry-based protein bi...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 5M2P12 JACSHoover et al., J. Am. Chem. Soc. 13...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAccurate and low-cost sensor localization is a critica...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brCommercial canmaking processes include drawing, redraw...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brNetwork-on-chip (NoC) is considered the next generatio...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brDesign optimization problems in chemical engineering a...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brThe problem of predicting the next request during a us...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brEducative sensemaking focuses on the needs of self-dir...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brHere we report that dentin matrix protein 1 (DMP1), an...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brSourcesSource: Michael Alley The Craft of Scientific W...
www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brValtencir Zucolottozuco@ifsc.usp.brwww.nanomedicina.co...
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Workshops escrita modulos_1_2

  1. 1. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop de Capacitação emEscrita CientíficaMódulo 1Prof. Dr. Valtencir ZucolottoLaboratório de Nanomedicina e NanotoxicologiaInstituto de Física de São Carlos, USPUSP, 2012Organização: Pró-Reitoria de Pesquisa - USP
  2. 2. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop OutlineModulo 1: O Gênero LiterárioSeções de Um Artigo CientíficoMódulo 2: Estrutura 1: AbstractMódulo 3: Estrutura 2: IntroductionMódulo 4: Estrutura 3: Results and Discussion, ConclusionMódulo 5: EstiloLinguagem 1: Especificidade, Complexidade e AmbiguidadeMódulo 6: Linguagem 2: Redundâncias, Ação no Verbo, Fluidez deTexto, Ritmo de EscritaMódulo 7: Linguagem 3: Plain English, Escrever em Inglês, PreposiçõesMódulo 8: Linguagem 4: Topic Sentences, Cover Letters, Final Remarks
  3. 3. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMódulo 1O Gênero LiterárioEstrutura 1
  4. 4. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhy?, What?, When?....
  5. 5. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhy to Publish??Publication is one of the most important stepsof the scientist’s workIf nobody knows, or can benefit from your work,Why being at work ??
  6. 6. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhat do we Publish?Scientists Publish Ideas !!
  7. 7. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWhen to Publish?When the initialquestion/problem/hypothesishad been answered/solved/tested !!!!!!
  8. 8. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brScientific Method /Hypothesis testingWhen to Publish?
  9. 9. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br-Distinct time scales for distinct areas;-Depends on the type of research:Breakthroughs and Innovative research.Advances on a specific, systematicinvestigation area.When to Publish?
  10. 10. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPublishing IdeasIdeasImplementation of the ResearchResultsIdeasNew Ideas?Output(Papers, Thesis, etc.)
  11. 11. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br1.General Considerations
  12. 12. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brLesson ZeroScientific writing as a “new” LiteraryGenre
  13. 13. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIn the very beginning…. Informal Letters exchanged by scientists.A bit of History…1665: Creation of the first scientific periodical: ThePhilosophical Transactions of the Royal Society.This new arena for discussion led to the development ofa new genre:The Scientific Report
  14. 14. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAudienceWho will read your paper?Highly technical journal vs. less specific ones.
  15. 15. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brClarity and ConcisionReport your results clearlyUse as few words as necessarySave words!!
  16. 16. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brReferencesAll information or ideas must be referenced!Including your own work
  17. 17. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br2.Sections of a Regular Paper
  18. 18. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brTypes of Scientific PublicationsThesisEncyclopediasResearchArticlesShortCommunications/LettersBooksRegularPapersReviews
  19. 19. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brGeneralSpecificAdapted from: Hill et al., Teaching ESL students to read and writeexperimental papers, TESOL Quarterly, 16: 333, 1982:Organization of a paperGeneralMethodologyResultsDiscussionIntroductionConclusionsAbstractReferencesTitle, Authors and Affiliations
  20. 20. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brTitle, Authors and AffiliationsA good Title describes the contents of thepaperFunction: to attract reader’s attentionUse specific words strongly associated withthe outcome of the paper: Keywords
  21. 21. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExample 1: A paper reporting on the influence of themolecular weight on the mechanical properties of Polyanilinethin films:Title 1: Mechanical properties of Polyaniline filmsPoor, too general!Title, Authors and Affiliations
  22. 22. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brTitle 2: The influence of the MW on the Mechanicalproperties of polyaniline spin-coated filmsExpresses the main idea of the work, the kind of film and itsfabrication technique.Keywords Included: mechanical properties, polyaniline,spin coatedTitle, Authors and Affiliations
  23. 23. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brOK!! The author describes the most important resultshortly and conciselyTitle:Metal-Polymer nanocomplexes induce spontaneousregression of lung tumorsEmphasize your key findings whenever possibleTitle, Authors and Affiliations
  24. 24. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWho are the authors of a paper?Title, Authors and Affiliations
  25. 25. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brGuidelines to define authorship:All authors must be able to present/discuss/defendthe paper.Title, Authors and Affiliations
  26. 26. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAuthors Names Sequence:First NameThe researcher who did the work, junior researcher.Middle namesAnyone who intellectually contributed to the workLast NameThe responsible for the research: supervisor/ grouphead/ senior scientistTitle, Authors and Affiliations
  27. 27. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAffiliations usually include the following information:GroupDepartment, CenterInstitution, UniversityCity, Zip code, PO BoxCountryTitle, Authors and Affiliations
  28. 28. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAbstract
  29. 29. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContextualizationGapPurposeMethodologyResultsConclusionsA ModelAluísio, S.M. (1995). Ferramentas para Auxiliar a Escrita de Artigos Científicos em Inglês comoLíngua Estrangeira. Tese de Doutorado, IFSC-USP, 228 p.
  30. 30. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brSelf-assembly of components larger than molecules into ordered arrays is anefficient way of preparing microstructured materials with interesting mechanical andoptical properties. Although crystallization of identical particles or particles of differentsizes or shapes can be readily achieved, the repertoire of methods to assemble binarylattices of particles of the same sizes but with different properties is very limited. Thispaper describes electrostatic self-assembly of two types of macroscopic components ofidentical dimensions using interactions that are generated by contact electrification. Thesystems we have examined comprise two kinds of objects (usually spheres) made ofdifferent polymeric materials that charge with opposite electrical polarities when agitatedon flat, metallic surfaces. The interplay of repulsive interactions between like-chargedobjects and attractive interactions between unlike-charged ones results in the self-assembly of these objects into highly ordered, closed arrays. Remarkably, some of theassemblies that form are not electroneutral—that is, they possess a net charge. Wesuggest that the stability of these unusual structures can be explained by accounting forthe interactions between electric dipoles that the particles in the aggregates induce intheir neighbors.AbstractGrzybowski et al., Nature Materials 2, 241–245 (2003)
  31. 31. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br1) Context: Self-assembly of components larger than molecules into ordered arrays is anefficient way of preparing microstructured materials with interesting mechanical andoptical properties.2) GAP: Although crystallization of identical particles or particles of different sizes orshapes can be readily achieved, the repertoire of methods to assemble binary lattices ofparticles of the same sizes but with different properties is very limited.3) Purpose: This paper describes electrostatic self-assembly of two types of macroscopiccomponents of identical dimensions using interactions that are generated by contactelectrification.4) Methodology: The systems we have examined comprise two kinds of objects (usuallyspheres) made of different polymeric materials that charge with opposite electricalpolarities when agitated on flat, metallic surfaces.5) Results: The interplay of repulsive interactions between like-charged objects andattractive interactions between unlike-charged ones results in the self-assembly of theseobjects into highly ordered, closed arrays. Remarkably, some of the assemblies that formare not electroneutral—that is, they possess a net charge.6) Conclusions: We suggest that the stability of these unusual structures can beexplained by accounting for the interactions between electric dipoles that the particles inthe aggregates induce in their neighbors.AbstractGrzybowski et al., Nature Materials 2, 241–245 (2003)
  32. 32. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIntroduction
  33. 33. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIntroductionContextualizationSumarizing PreviousResearchPurposeGeneralSpecificYour FieldYour work
  34. 34. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMethodology
  35. 35. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMethodologyMaterialsWhat materials were employed?Where did the materials come from?Methods/ProceduresReference to any well established methods andanalysesDetails concerning the procedure adoptedJustifying the procedures adoptedEquipmentEquipment employedData analysesMethods used for data processing and analyses
  36. 36. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brResults and Discussion
  37. 37. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brResultsIntroduction(purpose)Results and Discussion(Key Results)
  38. 38. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brConclusion
  39. 39. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brIn contrast to the Introduction, theconclusions section starts the Specific–to–General Movement.Conclusion
  40. 40. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brKey findingsInterpretation of main ResultsContribution to the fieldSpecificGeneralConclusion
  41. 41. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brReferencesAll information or ideas must be referenced!Including your own workAlways consult the Journal’s Guide for AuthorsThere are a number of different formats/styles you mayuse to cite other’s work in the text, or arrange thereferences list:
  42. 42. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExamples―….However, recent reports have been made on the fabrication ofultrathin films of metallic phthalocyanines and polyelectrolytesvia the electrostatic layer-by-layer technique (LBL).10(10) Lutt, M.; Fitzsimmons, M. R.; Li, D. Q. J. Phys. Chem. B 1998,102, 400.1. The citation-sequence systemReferences are numbered in the order they appear in the text.References
  43. 43. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExamples―….The layer-by-layer (LbL) technique has been largely employed inthe immobilization of proteins and other biomolecules followingthe pioneering work of Lvov et al. [Lvov et al., 1993; Lvov et al.,1995]….‖Lvov, Y., Ariga, K., Ichinose, I., Kunitake, T., 1995. Assembly of multicomponentprotein films by means of electrostatic layer-by-layer adsorption. J. Am. Chem.Soc.117, 6117- 6123.Lvov, Y., Decher, G., Sukhorukov, G. 1993. Assembly of Thin Films by Means ofSuccessive Deposition of Alternate Layers of DNA andv Poly(allylamine).Macromolecules 26, 5396-5399.2. The name-year systemReferences are listed alphabetically, using the first author´s last name.References
  44. 44. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brA Suggested Sequence….Results and DiscussionsConclusionsIntroductionTitleExperimentalAbstract
  45. 45. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brBegin writing in EnglishTake your notes in EnglishFinal version of a paper translated intoEnglishTranslations ??
  46. 46. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPlagiarismYou may cite others’ words, data, etc. usingyour own words;Do not paraphrase other author´s textDo not paraphrase your early papers.
  47. 47. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brhttp://www.fapesp.br/boaspraticas/codigo_fapesp0911.pdfPlagiarism
  48. 48. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPlagiarism
  49. 49. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br-Introduction to Journal-Style Scientific Writing:http://abacus.bates.edu/~ganderso/biology/resources/writing/HTWgeneral.html-http://www.inter-biotec.com/biowc/style.htmlSources-Scientific Writing, Easy When ou Know How, Peat, J., Elliot, E., Baur, L.,Keena, V., BMJ Books, 2009-Hill et al., Teaching ESL students to read and write experimental papers,TESOL Quarterly, 16: 333, 1982:-Int. Committee of Medical J. Editors, Ann. Intern. Med., 1997, 126, 36.
  50. 50. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brValtencir Zucolottozuco@ifsc.usp.brwww.nanomedicina.com.brwww.lnn.ifsc.usp.brwww.twitter.com/NanomedicinaInstituto de Física de São Carlos - USPMuito Obrigadowww.twitter.com/escreverartigoswww.twitter.com/writingpapers
  51. 51. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop de Capacitação emEscrita CientíficaMódulo 2Prof. Dr. Valtencir ZucolottoLaboratório de Nanomedicina e NanotoxicologiaInstituto de Física de São Carlos, USPUSP, 2012Organização: Pró-Reitoria de Pesquisa - USP
  52. 52. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brWorkshop OutlineModulo 1: O Gênero LiterárioSeções de Um Artigo CientíficoMódulo 2: Estrutura 1: AbstractMódulo 3: Estrutura 2: IntroductionMódulo 4: Estrutura 3: Results and Discussion, ConclusionMódulo 5: EstiloLinguagem 1: Especificidade, Complexidade e AmbiguidadeMódulo 6: Linguagem 2: Redundâncias, Ação no Verbo, Fluidez deTexto, Ritmo de EscritaMódulo 7: Linguagem 3: Plain English, Escrever em Inglês, PreposiçõesMódulo 8: Linguagem 4: Topic Sentences, Cover Letters, Final Remarks
  53. 53. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brMódulo 2Estrutura 1: Abstract
  54. 54. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brGeneralSpecificOrganization of a paperGeneralAdapted from: Hill et al., Teaching ESL students to read and writeexperimental papers, TESOL Quarterly, 16: 333, 1982:MethodologyResultsDiscussionIntroductionConclusionsAbstractReferencesTitle, Authors and Affiliations
  55. 55. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAbstract
  56. 56. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAbstractAn abstract summarizes the major aspects of thepaperThe abstract contains only text
  57. 57. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brInformativeContains all therelevant information ofthe paperDescriptiveDescribes only thenature/purpose of thestudyXInformativeContains all therelevant information ofthe paperMichael Alley The Craft of Scientific Writing, 3rd edition (Springer-Verlag, 1996).Abstract
  58. 58. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brStyle- Past Tense (whenever possible);- Active voice preferred;- Concise, complete sentences.Abstract
  59. 59. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContextualizationGapPurposeMethodologyResultsConclusionsAluísio, S.M. (1995). Ferramentas para Auxiliar a Escrita de Artigos Científicos em Inglês comoLíngua Estrangeira. Tese de Doutorado, IFSC-USP, 228 p.Abstract
  60. 60. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brJ Pharm Pharmaceut Sci 8(2):162-178, 2005Abstract
  61. 61. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brExamples from the Literature
  62. 62. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brSelf-assembly of components larger than molecules into ordered arraysis an efficient way of preparing microstructured materials with interestingmechanical and optical properties. Although crystallization of identical particles orparticles of different sizes or shapes can be readily achieved, the repertoire ofmethods to assemble binary lattices of particles of the same sizes but withdifferent properties is very limited. This paper describes electrostatic self-assembly of two types of macroscopic components of identical dimensions usinginteractions that are generated by contact electrification. The systems we haveexamined comprise two kinds of objects (usually spheres) made of differentpolymeric materials that charge with opposite electrical polarities when agitatedon flat, metallic surfaces. The interplay of repulsive interactions between like-charged objects and attractive interactions between unlike-charged ones resultsin the self-assembly of these objects into highly ordered, closed arrays.Remarkably, some of the assemblies that form are not electroneutral—that is,they possess a net charge. We suggest that the stability of these unusualstructures can be explained by accounting for the interactions between electricdipoles that the particles in the aggregates induce in their neighbors.Grzybowski et al., Nature Materials 2, 241–245 (2003)Case 1 M2P1 Nature MatAbstract
  63. 63. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.br1) Context: Self-assembly of components larger than molecules into ordered arrays is anefficient way of preparing microstructured materials with interesting mechanical andoptical properties.2) GAP: Although crystallization of identical particles or particles of different sizes orshapes can be readily achieved, the repertoire of methods to assemble binary lattices ofparticles of the same sizes but with different properties is very limited.3) Purpose: This paper describes electrostatic self-assembly of two types of macroscopiccomponents of identical dimensions using interactions that are generated by contactelectrification.4) Methodology: The systems we have examined comprise two kinds of objects (usuallyspheres) made of different polymeric materials that charge with opposite electricalpolarities when agitated on flat, metallic surfaces.5) Results: The interplay of repulsive interactions between like-charged objects andattractive interactions between unlike-charged ones results in the self-assembly of theseobjects into highly ordered, closed arrays. Remarkably, some of the assemblies that formare not electroneutral—that is, they possess a net charge.6) Discussion/Conclusions: We suggest that the stability of these unusual structurescan be explained by accounting for the interactions between electric dipoles that theparticles in the aggregates induce in their neighbors.Abstract
  64. 64. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brBioinert polyelectrolyte multilayers comprised of poly(acrylic acid)and polyacrylamide were deposited on colloidal particles (1.7 m diameter)at low pH conditions by layer-by-layer assembly using hydrogen-bondinginteractions. The multilayer films were coated uniformly on the colloidalparticles without causing any flocculation of the colloids, and the depositedfilms were subsequently cross-linked by a single treatment of acarbodiimide aqueous solution. The lightly cross-linked multilayer filmsshow excellent stability at physiological conditions (pH 7.4, phosphate-buffered saline), whereas untreated multilayer films dissolved. Themultilayer-coated surfaces, both on flat substrates and on colloidalparticles, exhibit excellent resistance toward mammalian cell adhesion.With this new solution-based cross-linking method, bioinert H-bondedmultilayer coatings offer potential for biomedical applications.Yang et al, Langmuir; 2004; 20; 5978Case 2M2P2 Nature MatAbstract
  65. 65. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContext??Gap??Purpose?: Bioinert polyelectrolyte multilayers comprised of poly(acrylicacid) and polyacrylamide were deposited on colloidal particles (1.7 mdiameter) at low pH conditions by layer-by-layer assembly using hydrogen-bonding interactions.Methodology: The multilayer films were coated uniformly on the colloidalparticles without causing any flocculation of the colloids, and the depositedfilms were subsequently cross-linked by a single treatment of a carbodiimideaqueous solution.Results: The lightly cross-linked multilayer films show excellent stability atphysiological conditions (pH 7.4, phosphate-buffered saline), whereasuntreated multilayer films dissolved. The multilayer-coated surfaces, both onflat substrates and on colloidal particles, exhibit excellent resistance towardmammalian cell adhesion.Conclusions: With this new solution-based cross-linking method, bioinert H-bonded multilayer coatings offer potential for biomedical applications.Abstract
  66. 66. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brDendrimers are branched, synthetic polymers with layered architecturesthat show promise in several biomedical applications. By regulatingdendrimer synthesis, it is possible to precisely manipulate both theirmolecular weight and chemical composition, thereby allowing predictabletuning of their biocompatibility and pharmacokinetics. Advances in ourunderstanding of the role of molecular weight and architecture on the invivo behavior of dendrimers, together with recent progress in the designof biodegradable chemistries, has enabled the application of thesebranched polymers as anti-viral drugs, tissue repair scaffolds, targetedcarriers of chemotherapeutics and optical oxygen sensors. Before suchproducts can reach the market, however, the field must not only addressthe cost of manufacture and quality control of pharmaceutical-gradematerials, but also assess the long-term human and environmental healthconsequences of dendrimer exposure in vivo.Lee et al., Nature Biotechnology 23, 1517, 2005 (Review)Case 3M2P3 Nature BiotechAbstract
  67. 67. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brContext: Dendrimers are branched, synthetic polymers with layeredarchitectures that show promise in several biomedical applications. Byregulating dendrimer synthesis, it is possible to precisely manipulateboth their molecular weight and chemical composition, thereby allowingpredictable tuning of their biocompatibility and pharmacokinetics.Advances in our understanding of the role of molecular weight andarchitecture on the in vivo behavior of dendrimers, together with recentprogress in the design of biodegradable chemistries, has enabled theapplication of these branched polymers as anti-viral drugs, tissue repairscaffolds, targeted carriers of chemotherapeutics and optical oxygensensors.Gap: Before such products can reach the market, however, the fieldmust not only address the cost of manufacture and quality control ofpharmaceutical-grade materials, but also assess the long-term humanand environmental health consequences of dendrimer exposure in vivo.Descriptive or Informative ??Abstract
  68. 68. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 1Metallophthalocyanines (MPcs) are conjugated macrocyclic compounds that have beenwidely investigated in different scientific and technological fields. However, one of thelimitations of the use of MPcs in technological devices is the limited solubility of thesemolecules, which makes difficult the deposition as thin films. This paper describes the use ofthe layer-by-layer technique to obtain thin films of cobalt tetrasulfonated phthalocyanine(CoTsPc) and the polyelectrolytes poly(allylamine hydrochloride) (PAH) and poly(amidoamine) generation 4 (PAMAM G4). In addition to the structural investigations that revealedthe nanoscale organization of the films, the possibility of using these platforms as humiditysensors has also been exploredA comprehensive SPR investigation on film growthreproduced dynamically the deposition process and provided an estimation of the layers’thicknesses. The electrical conductivity of the films deposited on interdigitated electrodeswas found to be very sensitive to water vapor. This sensitivity is caused by the positioning ofthe Pc rings along the multilayers, which is a consequence of the self-assembly method.These results point to the development of a phthalocyanine-based humidity sensor obtainedfrom a simple thin film deposition technique, whose outstanding ability to tailor molecularorganization was crucial to achieve such high sensitivity.M2P4Centurion et al., J. Nanosc. Nanotech, 2012 in press
  69. 69. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 2Vibrational energy flow into reactants, and out of products, plays a keyrole in chemical reactivity, so understanding the microscopic detail of thepathways and rates associated with this phenomenon is of considerableinterest. Here, we use molecular dynamics simulations to model thevibrational relaxation that occurs during the reaction CN1c-C6H12 HCN1c-C6H11 in CH2Cl2, which produces vibrationally hot HCN. Thecalculations reproduce the observed energy distribution, and show thatHCN relaxation follows multiple timescales. Initial rapid decay occursthrough energy transfer to the cyclohexyl co-product within the solventcage, and slower relaxation follows once the products diffuse apart. Re-analysis of the ultrafast experimental data also provides evidence for thedual timescales. These results, which represent a formal violation ofconventional linear response theory, provide a detailed picture of theinterplay between fluctuations in organic solvent structure and thermalsolution-phase chemistry.M2P9 Nat ChemGlowacki et al., Nature Chem., 3, 850, 2011
  70. 70. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 3Polymer nanoparticles are widely used as a highly generalizable tool to entrap arange of different drugs for controlled or site-specific release. However, despitenumerous studies examining the kinetics of controlled release, the biologicalbehavior of such nanoparticles remains poorly understood, particularly withrespect to endocytosis and intracellular trafficking. We synthesizedpolyethyleniminedecorated polymer nanospheres (ca. 100 250 nm) of the typecommonly used for drug release and used correlated electron microscopy,fluorescence spectroscopy and microscopy, and relaxometry to track endocytosisin neural cells. These capabilities provide insight into how polyethyleniminemediates the entry of nanoparticles into neural cells and show that polymernanosphere uptake involves three distinct steps, namely, plasma membraneattachment, fluid-phase as well as clathrin- and caveolinindependent endocytosis,and progressive accumulation in membrane-bound intracellular vesicles. Thesefindings provide detailed insight into how the intracellular delivery of nanoparticlesis mediated by polyethylenimine, which is presently the most commonly usednonviral gene transfer agent. This fundamental knowledge may also assist in thepreparation of next-generation nonviral vectors.M2P10 ACS NanoEvans et al., ACS Nano, In Press
  71. 71. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 4Currently, mass spectrometry-based protein bioanalysis is primarily achieved throughmonitoring the representative peptide(s) resulting from analyte protein digestion. However,this approach is often incapable of differentiating the measurement of protein analyte fromits post-translational modifications (PTMs) and/or potential biotransformation (BTX)products. This disadvantage can be overcome by direct measurement of the intact proteinanalytes. Selected reaction monitoring (SRM) on triple quadrupole mass spectrometers hasbeen used for the direct measurement of intact protein. However, the fragmentationefficiency though the SRM process could be limited in many cases, especially for highmolecular weight proteins. In this study, we present a new strategy of intact proteinbioanalysis by high-resolution (HR) full scan mass spectrometry using human lysozyme as amodel protein. An HR linear ion-trap/ Orbitrap mass spectrometer was used for detection. Acomposite of isotopic peaks from one or multiple charge states can be isolated from thebackground and used to improve the signal-to-noise ratio. The acquired data wereprocessed by summing extracted ion chromatograms (EIC) of the 10 most intense isotopicions of octuply protonated lysozyme. Quantitation of the plasma lysozyme was conductedby utilizing high resolving power and an EIC window fitting to the protein molecular weight.An assay with a linear dynamic range from 0.5 to 500 μg/mL was developed with goodaccuracy and precision. The assay was successfully employed for monitoring the level ofendogenous lysozyme and a potential PTM in human plasma. The current instrumentationlimitations and potential advantages of this approach for the bioanalysis of large proteinsare discussed.M2P11 Anal ChemJuan et al., Analytical Chem, In Press
  72. 72. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brPrática 5M2P12 JACSHoover et al., J. Am. Chem. Soc. 133, 16901, 2011
  73. 73. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brAccurate and low-cost sensor localization is a critical requirement for the deployment ofwireless sensor networks in a wide variety of applications. Low-power wireless sensors maybe many hops away from any other sensors with a priori location information. In cooperativelocalization, sensors work together in a peer-to-peer manner to make measurements andthen form a map of the network. Various application requirements (such as scalability,energy efficiency, and accuracy) will influence the design of sensor localization systems. Inthis article, we describe measurement-based statistical models useful to describe time-of-arrival (TOA), angle-of-arrival (AOA), and received-signal-strength (RSS) measurements inwireless sensor networks. Wideband and ultra-wideband (UWB) measurements, and RFand acoustic media are also discussed. Using the models, we show how to calculate aCramér-Rao bound (CRB) on the location estimation precision possible for a given set ofmeasurements. This is a useful tool to help system designers and researchers selectmeasurement technologies and evaluate localization algorithms. We also briefly survey alarge and growing body of sensor localization algorithms. This article is intended toemphasize the basic statistical signal processing background necessary to understand thestate-of-the-art and to make progress in the new and largely open areas of sensor networklocalization research.Prática 6IEEE Signal Processing Magazine, 2005, p 55M2P5 IEEE Sig Proc
  74. 74. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brCommercial canmaking processes include drawing, redrawing and several ironing operations.It is experimentally observed that during the drawing and redrawing processes earingdevelops, but during the ironing processes earing is reduced. It is essential to understand theearing mechanism during drawing and ironing for an advanced material modeling. A newanalytical approach that relates the earing profile to r-value and yield stress directionalities ispresented in this work. The analytical formula is based on the exact integration of thelogarithmic strain. The derivation is for a cylindrical cup under the plane stress conditionbased on rigid perfect plasticity while force equilibrium is not considered. The earing profile isobtained solely from anisotropic plastic properties in simple tension. The earing mechanism isexplained from the present theory with explicit formulae. It has been proved that earing is thecombination of the contributions from r-value and yield stress directionalities. From adirectionality (y-axis) vs. angle from the rolling (x-axis) plot, the earing profile is generated tobe a scaled mirror image of the r-value directionality with respect to 90 (x = 90) and also ascaled mirror image of the yield stress directionality with respect to the reference yield stress(y = 1). Three different materials (Al–5% Mg alloy, AA 2090-T3 and AA 3104 RPDT controlcoil) are considered for verification purposes. This approach provides a fundamental basis forunderstanding the earing mechanism. In practice, the present theory is also very useful for theprediction of the earing profile of a drawn and iron cup and its related convolute cut-edgedesign for an earless cup.Prática 7International Journal of Plasticity 27 (2011) 1165M2P6 Int J Plast
  75. 75. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brNetwork-on-chip (NoC) is considered the next generation ofcommunication infrastructure, which will be omnipresent in differentenvironments. In the platform-based design methodology, an applicationis implemented by a set of collaborating intellectual property (IP) blocks.The selection of the most suited set of IPs as well as their physicalmapping onto the NoC to efficiently implement the application at handare two hard combinatorial problems. In this article, we propose aninnovative power-aware multi-objective evolutionary algorithm to performthe assignment and mapping stages of a platform-based NoC designsynthesis tool. Our algorithm uses the well-known multi-objectiveevolutionary algorithms NSGA-II and microGA as kernels. Theoptimisation is driven by the required area and the imposed executiontime, considering that the decision maker’s restriction is the powerconsumption of the implementation.Prática 8International Journal of Electronics, 97, 2010, 1163M2P7 Int J electron
  76. 76. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brDesign optimization problems in chemical engineering and in many other engineering domainsare characterized by the presence of a large number of discrete and continuous decisionvariables, complex nonlinear models that restrict the search space, nonlinear cost functions,and the presence of many local optima. The classical approach to such problems are mixedinteger nonlinear program solvers that work on a superstructure formulation which explicitlyrepresents all design alternatives. The structural decisions lead to a large number of discretevariables and an exponential increase in the computational effort. The mathematicalprogramming (MP) methods which are usually employed to solve the continuous subproblemsthat arise by fixing the discrete variables provide only one local optimum which dependsstrongly on the initialization. Thus standard methods may not find the global optimum despitelong computation times. In this contribution we introduce a memetic algorithm (MA) for theglobal optimization of a computational demanding real-world design problem from the chemicalengineering domain. The MA overcomes the problem of getting stuck in local optima by the useof an evolution strategy (ES) which addresses the global optimization of the design decisions,whereas a robust MP solver is used to handle complex nonlinear constraints as well as toimprove the individuals of the ES by performing a local search in continuous sub-spaces in anintegrated fashion. The MA is discussed in detail, the novel decomposition of the problem classat hand is analyzed and the MA is tested for the example of the optimal design of a reactivedistillation column with several thousand decision variables. The MA is the only algorithm thatfinds the global solution in reasonable computation times. The introduction of structuraldecisions and additional constraints and discontinuous penalty terms lead only to a moderateincrease in the computational effort which demonstrates the potential of this class of memeticalgorithms in real-world design optimization problems.Prática 9Urselmann, et al., IEEE Transactions on Evolutionary Computation, 15, 2011, 659M2P13 IEEE T.E.C.
  77. 77. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brThe problem of predicting the next request during a user’s navigation sessionhas been extensively studied. In this context, higher-order Markov models havebeen widely used to model navigation sessions and to predict the nextnavigation step, while prediction accuracy has been mainly evaluated with the hitand miss score.We claim that this score, although useful, is not sufficient forevaluating next link prediction models with the aim of finding a sufficient order ofthe model, the size of a recommendation set, and assessing the impact ofunexpected events on the prediction accuracy. Herein, we make use of avariable length Markov model to compare the usefulness of three alternatives tothe hit and miss score: the Mean Absolute Error, the Ignorance Score, and theBrier score. We present an extensive evaluation of the methods on real datasets and a comprehensive comparison of the scoring methods.Prática 10Borges et al., International Journal of Information Technology & Decision Making, 9, 2010, 547.M2P14 Int J Inf
  78. 78. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brEducative sensemaking focuses on the needs of self-directed learners, a nonexpertpopulation of thinkers who must locate relevant information sources, evaluate theapplicability and accuracy of digital resources for learning, and determine how and when touse these resources to complete educational tasks. Self-directed learners face asensemaking paradox: They must employ deep-level thinking skills to process informationsources meaningfully, but they often lack the requisite domain knowledge needed todeeply analyze information sources and to successfully integrate incoming information withtheir own existing knowledge. In this article, we focus on the needs of college-agedstudents engaged in learning about natural sciences using web-based learning resources.We explored the impact of cognitive personalization technologies on students’sensemaking processes using a controlled study in which students’ cognitive andmetacognitive processes were analyzed as they completed a common educational task:writing an essay.We coded students’ observable on-screen behaviors, selfreportedprocesses, final essays, and responses to domain assessments to assess benefits ofpersonalization technologies on students’ educative sensemaking. Results show thatpersonalization supported students’ analysis of knowledge representations, helpedstudents work with their representations in meaningful ways, and supported effectiveencoding of new knowledge. We discuss implications for new technologies to helpstudents overcome the educative sensemaking paradox.Prática 11Butcher et al., Human–Computer Interaction, 26, 2011,123.M2P15 Human Comp Int
  79. 79. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brHere we report that dentin matrix protein 1 (DMP1), an acidic protein, can nucleate theformation of hydroxyapatite in vitro in a multistep process that begins by DMP1 bindingcalcium ions and initiating mineral deposition.Bones and teeth are biocomposites that require controlled mineral deposition during theirself-assembly to form tissues with unique mechanical properties.Acidic extracellular matrix proteins play a pivotal role during biomineral formation.The nucleated amorphous calcium phosphate precipitates ripen and nanocrystals form.Subsequently, these expand and coalesce into microscale crystals elongated in the c-axis direction.Protein-mediated initiation of nanocrystals, as discussed here, might provide a newmethodology for constructing nanoscale composites by self-assembly of polypeptideswith tailor-made peptide sequences.However, the mechanisms of protein-mediated mineral initiation are far from understood.Characterization of the functional domains in DMP1 demonstrated that intermolecularassembly of acidic clusters into a -sheet template was essential for the observed mineralnucleation.Nature Materials 2, 552–558, 2003Prática 12Reordene as frases da maneira correta, categorizando-as:M2P8 Nature Mat
  80. 80. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brSourcesSource: Michael Alley The Craft of Scientific Writing, 3rd edition (Springer-Verlag, 1996).Aluísio, S.M. (1995). Ferramentas para Auxiliar a Escrita de Artigos Científicos em Inglês como Língua Estrangeira. Tesede Doutorado, IFSC-USP, 228 p.Hill et al., Teaching ESL students to read and write experimental papers, TESOL Quarterly, 16: 333, 1982:Centurion et al., J. Nanosc. Nanotech, 2011 in pressGrzybowski et al., Nature Materials 2, 241–245 (2003)Yang et al, Langmuir; 2004; 20; 5978Lee et al., Nature Biotechnology 23, 1517, 2005 (Review)Glowacki et al., Nature Chem., 3, 850, 2011Evans et al., ACS Nano, In PressJuan et al., Analytical Chem, In PressHoover et al., J. Am. Chem. Soc. 133, 16901, 2011IEEE Signal Processing Magazine, 2005, p 55International Journal of Plasticity 27 (2011) 1165International Journal of Electronics, 97, 2010, 1163Urselmann, et al., IEEE Transactions on Evolutionary Computation, 15, 2011, 659Borges et al., International Journal of Information Technology & Decision Making, 9, 2010, 547.Butcher et al., Human–Computer Interaction, 26, 2011,123.Nature Materials 2, 552–558, 2003
  81. 81. www.nanomedicina.com.brProf. Dr. Valtencir Zucolottozuco@ifsc.usp.brValtencir Zucolottozuco@ifsc.usp.brwww.nanomedicina.com.brwww.lnn.ifsc.usp.brwww.twitter.com/NanomedicinaInstituto de Física de São Carlos - USPMuito Obrigadowww.twitter.com/escreverartigoswww.twitter.com/writingpapers

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