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Introduction to Genetic Engineering

Introduction to Genetic Engineering



An introduction to genetic engineering powerpoint that I used in my 8th grade field placement

An introduction to genetic engineering powerpoint that I used in my 8th grade field placement



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    Introduction to Genetic Engineering Introduction to Genetic Engineering Presentation Transcript

    •  It is the direct manipulation of an organism’s genome using modern DNA technology … also called genetic modification A genome is the entirety of an organism’s hereditary information
    •  Glow-in-the-dark cats  Venomous cabbage Web-spinning goats  Less flatulent cows
    •  Scientists have recently taken the gene that programs poison in scorpion tails and looked for ways to combine it with cabbage. This would limit pesticide use while still preventing caterpillars from damaging cabbage crops. These genetically modified cabbages would produce scorpion poison that kills caterpillars when they bite leaves — but the toxin is modified so it isn’t harmful to humans.
    •  Agriculture research scientists at the University of Alberta have identified the bacterium responsible for producing methane and designed a line of cattle that creates 25 percent less methane than the average cow.
    •  Researchers inserted a spiders’ dragline silk gene into the goats’ DNA in such a way that the goats would make the silk protein only in their milk. This “silk milk” could then be used to manufacture a web- like material called Biosteel.
    •  In 2007, South Korean scientists altered a cat’s DNA to make it glow in the dark and then took that DNA and cloned other cats from it — creating a set of fluffy, fluorescent felines. The researchers took skin cells from Turkish Angora female cats and used a virus to insert genetic instructions for making red fluorescent protein.
    •  The term cloning describes a number of different processes that can be used to produce genetically identical copies of a biological entity. The copied material, which has the same genetic makeup as the original, is referred to as a clone. They occur naturally and artificially
    •  Gene Cloning: produces copies of genes or segments of DNA Reproductive Cloning: produces copies of whole animals Therapeutic Cloning: produces embryonic stem cells for experiments aimed at creating tissues to replace injured or diseased tissues
    •  The procedure consists of inserting a gene from one organism, often referred to as "foreign DNA," into the genetic material of a carrier called a vector. Examples of vectors include bacteria, yeast cells, and viruses. After the gene is inserted, the vector is placed in laboratory conditions that prompt it to multiply, resulting in the gene being copied many times over.
    •  Remove DNA from an egg cell Replace with DNA from the animal you wish to clone by injection or electrical current Allow egg to develop into an early-stage embryo Finally, implant into the womb of a female of the animal you are trying to clone
    •  Could create genetically modified animals (sheep that produce milk that contains blood clotting protein) Create animals for food Bring back extinct species …. DINOSAURS!!!
    •  Very inefficient … the cloned sheep Dolly was the only embryo out of 277 that actually survived Numerous health issues including early death Minimal genetic variability
    •  Therapeutic cloning involves creating a cloned embryo for the sole purpose of producing embryonic stem cells with the same DNA as the donor cell. One of the human bodys master cells, with the ability to grow into any one of the bodys more than 200 cell types The best stem cells exist during the first five days of embryo The cells are harvested resulting in destruction of the embryo
    •  Applications  Stem cells can be used in experiments to help understand disease and create new treatments  New tissue formation Drawbacks  Stem cells are similar to cancer cells in that they can reproduce indefinitely and could develop mutations  It involves killing an embryo
    •  Read the articles on cloning Choose your side Write a paragraph explaining why you chose that side