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Atopic Dermatitis
AD: ICCAD II <ul><li>AD is a common chronic relapsing inflammatory skin disease characterized by: </li></ul><ul><li>Intens...
AD: ICCAD II (Cont’d) <ul><li>Early age of onset: </li></ul><ul><li>50% of cases diagnosed by 1 year of age. </li></ul><ul...
AD: ICCAD II (Cont’d) <ul><li>AD is often familial and frequently associated with asthma, food allergy, allergic rhinitis ...
AD: ICCAD II (Cont’d) <ul><li>Trigger factors:  </li></ul><ul><li>Increased prevalence:  10-15% of children (<yrs) are aff...
III-Diagnosis Atopic Dermatitis
AD: Clinical features Infantile phase (2 months – 2 years) <ul><li>Cheeks, forehead and body but sparing the diaper area. ...
AD: Clinical features (Cont’d) Childhood phase (2 – 12 years) <ul><li>Elbow and knee flexures, sides of neck and hand. </l...
AD: Clinical features (Cont’d) Adult phase (? atopic neurodermatitis) <ul><li>As childhood phase with lichenification of f...
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Hanifin & Rajak’s diagnostic criteria for AD (1980) Major criteria <ul><li>Adults: flexural lichenification or linearity. ...
Hanifin & Rajak’s diagnostic criteria for AD (Cont’d) Minor criteria 1. Xerosis. 2. Ichythosis, keratosis pilaris, palmar ...
 
 
 
 
 
 
 
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Medicine 6th year, Dermatology Tutorial (5th session/part two)

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September 5th, 2011

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Transcript of "Medicine 6th year, Dermatology Tutorial (5th session/part two)"

  1. 1. Atopic Dermatitis
  2. 2. AD: ICCAD II <ul><li>AD is a common chronic relapsing inflammatory skin disease characterized by: </li></ul><ul><li>Intense itching. </li></ul><ul><li>Dry skin. </li></ul><ul><li>Inflammation. </li></ul><ul><li>Exudation. </li></ul><ul><li>Physical & emotional distress for pts. and their families. </li></ul><ul><li>> psoriasis. </li></ul><ul><li>= early onset of DM. </li></ul>
  3. 3. AD: ICCAD II (Cont’d) <ul><li>Early age of onset: </li></ul><ul><li>50% of cases diagnosed by 1 year of age. </li></ul><ul><li>1/3 of patients having persistent disease throughout adulthood. </li></ul><ul><li>Vast majority of cases are mild. </li></ul>
  4. 4. AD: ICCAD II (Cont’d) <ul><li>AD is often familial and frequently associated with asthma, food allergy, allergic rhinitis and recurrent 2ry skin infections. </li></ul><ul><li>AD may increase subsequent risk or severity of asthma. </li></ul>
  5. 5. AD: ICCAD II (Cont’d) <ul><li>Trigger factors: </li></ul><ul><li>Increased prevalence: 10-15% of children (<yrs) are affected. </li></ul><ul><li>Stress. </li></ul><ul><li>Irritants. </li></ul><ul><li>Microbes, and </li></ul><ul><li>Allergens. </li></ul>
  6. 6. III-Diagnosis Atopic Dermatitis
  7. 7. AD: Clinical features Infantile phase (2 months – 2 years) <ul><li>Cheeks, forehead and body but sparing the diaper area. </li></ul><ul><li>Erythema, itchy edematous papules with rubbing  exudative & crusted. </li></ul><ul><li>2ry infection and lymphadenopathy. </li></ul>
  8. 8. AD: Clinical features (Cont’d) Childhood phase (2 – 12 years) <ul><li>Elbow and knee flexures, sides of neck and hand. </li></ul><ul><li>Itchy papules and lichenified plaques. </li></ul><ul><li>Scratching  lichenification. </li></ul>
  9. 9. AD: Clinical features (Cont’d) Adult phase (? atopic neurodermatitis) <ul><li>As childhood phase with lichenification of flexures. </li></ul><ul><li>Hand dermatitis, upper eyelid dermatitis. </li></ul><ul><li>Dry skin and keratosis pilaris. </li></ul>
  10. 34. Hanifin & Rajak’s diagnostic criteria for AD (1980) Major criteria <ul><li>Adults: flexural lichenification or linearity. </li></ul><ul><li>Children and infants: facial, extensor. </li></ul>1. Pruritus. 2. Typical morphology and distribution 3. Chronic or relapsing dermatitis. 4. Personal or family history of atopy.
  11. 35. Hanifin & Rajak’s diagnostic criteria for AD (Cont’d) Minor criteria 1. Xerosis. 2. Ichythosis, keratosis pilaris, palmar hyperlinearity. 3. Type I skin test reactivitiy. 4. Elevated serum IgE. 5. Early age at onset. 6. Tendency to skin infections. 7. Infraorbital darkening and linearity. 8. Atypical vascular responses.
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