Hanifin & Rajak’s diagnostic criteria for AD (1980) Major criteria
Adults: flexural lichenification or linearity.
Children and infants: facial, extensor.
1. Pruritus. 2. Typical morphology and distribution 3. Chronic or relapsing dermatitis. 4. Personal or family history of atopy.
Hanifin & Rajak’s diagnostic criteria for AD (Cont’d) Minor criteria 1. Xerosis. 2. Ichythosis, keratosis pilaris, palmar hyperlinearity. 3. Type I skin test reactivitiy. 4. Elevated serum IgE. 5. Early age at onset. 6. Tendency to skin infections. 7. Infraorbital darkening and linearity. 8. Atypical vascular responses.