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THROMBOELASTOGRAPHY
TEG Principle
 
LY30 measures the rate of amplitude reduction 30 minutes after MA. This measurement gives an indication of the stability o...
TEG
TEG Parameters <ul><li>r time </li></ul><ul><li>Time from initiation of trace until the amplitude of the trace reaches 2 m...
TEG Parameters <ul><li>r   time  ↑  by </li></ul><ul><ul><li>Factor deficiency  </li></ul></ul><ul><ul><li>Anti-coagulatio...
TEG Parameters <ul><li>K time </li></ul><ul><li>Time from r until amplitude reaches 20 mm </li></ul><ul><li>Measure of clo...
TEG Parameters <ul><li>k time  ↑  or  angle  ↓ by </li></ul><ul><ul><li>Factor deficiency </li></ul></ul><ul><ul><li>Hypof...
TEG Parameters <ul><li>Maximum amplitude   </li></ul><ul><li>is a direct function of the maximum dynamic properties of fib...
TEG Parameters <ul><li>LY30 </li></ul><ul><li>measures % decrease in amplitude 30 min post-MA  </li></ul><ul><li>gives mea...
 
 
 
<ul><li>Factor Deficiency </li></ul><ul><li>Heparin effect </li></ul>
<ul><li>Thrombocytopenia </li></ul>
<ul><li>Fibrinolysis </li></ul>
<ul><li>Hypercoagulable </li></ul>
<ul><li>Severe Coagulopathy </li></ul>
<ul><li>Heparin Effect </li></ul>
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thromboelastography

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thromboelastography principle and interpetation

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Transcript of "thromboelastography"

  1. 1. THROMBOELASTOGRAPHY
  2. 2. TEG Principle
  3. 4. LY30 measures the rate of amplitude reduction 30 minutes after MA. This measurement gives an indication of the stability of the clot. LY30 (EPL) MA, or Maximum Amplitude, is a direct function of the maximum dynamic properties of fibrin and platelet bonding and represents the ultimate strength of the fibrin clot. MA K time is a measure of the rapidity to reach a certain level of clot strength. K The  value measures the rapidity (kinetics) of fibrin build-up and cross-linking, that is, the speed of clot strengthening.  R is the time of latency from the time that the blood was placed in the TEG® analyzer until the initial fibrin formation. R
  4. 5. TEG
  5. 6. TEG Parameters <ul><li>r time </li></ul><ul><li>Time from initiation of trace until the amplitude of the trace reaches 2 mm </li></ul><ul><li>Corresponds to initial fibrin formation </li></ul><ul><li>Functionally related to plasma clotting and inhibitor activity </li></ul>
  6. 7. TEG Parameters <ul><li>r time ↑ by </li></ul><ul><ul><li>Factor deficiency </li></ul></ul><ul><ul><li>Anti-coagulation </li></ul></ul><ul><ul><li>Severe hypofibrinogenaemia </li></ul></ul><ul><ul><li>Severe thrombocytopenia </li></ul></ul><ul><li>r time ↓ by </li></ul><ul><ul><li>Hypercoagulability syndromes </li></ul></ul>
  7. 8. TEG Parameters <ul><li>K time </li></ul><ul><li>Time from r until amplitude reaches 20 mm </li></ul><ul><li>Measure of clot formation kinetics </li></ul><ul><li> angle </li></ul><ul><li>Measures the rapidity of fibrin polymerization </li></ul><ul><li>assesses rate of clot formation </li></ul>
  8. 9. TEG Parameters <ul><li>k time ↑ or angle ↓ by </li></ul><ul><ul><li>Factor deficiency </li></ul></ul><ul><ul><li>Hypofibrinogenaemia </li></ul></ul><ul><ul><li>Thrombocytopenia </li></ul></ul><ul><li>k time ↓ or angle ↑ by </li></ul><ul><ul><li>Hypercoagulability state </li></ul></ul>
  9. 10. TEG Parameters <ul><li>Maximum amplitude </li></ul><ul><li>is a direct function of the maximum dynamic properties of fibrin and platelet bonding </li></ul><ul><li>represents the maximum strength of the fibrin clot </li></ul><ul><li>Correlates more to platelet function and to lesser extent to fibrinogen </li></ul><ul><li>MA ↓ by </li></ul><ul><li>Thrombocytopenia </li></ul><ul><li>Thrombocytopathy </li></ul><ul><li>Fibrinolysis </li></ul><ul><li>Hypofibrinogenemia </li></ul>
  10. 11. TEG Parameters <ul><li>LY30 </li></ul><ul><li>measures % decrease in amplitude 30 min post-MA </li></ul><ul><li>gives measure of degree of fibrinolysis </li></ul><ul><li>normal range < 7.5% </li></ul><ul><li>LY60 </li></ul><ul><ul><li>60 minute post-MA data </li></ul></ul>
  11. 15. <ul><li>Factor Deficiency </li></ul><ul><li>Heparin effect </li></ul>
  12. 16. <ul><li>Thrombocytopenia </li></ul>
  13. 17. <ul><li>Fibrinolysis </li></ul>
  14. 18. <ul><li>Hypercoagulable </li></ul>
  15. 19. <ul><li>Severe Coagulopathy </li></ul>
  16. 20. <ul><li>Heparin Effect </li></ul>
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