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Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
Pf Ts  Overview
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Pf Ts Overview


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  • 1. Pulmonary Function Tests An Overview Dr. Taher El Naggar Professor of Pulmonary Medicine Ain Shams University
  • 2.
    • What is Respiration ?
  • 3.
    • It is a process by which cells utilize O2 produce Co2 & exchange the gases with atmosphere.
  • 4.
    • External respiration
    • a) Pulmonary ventilation
    • b) Gas exchange across alveolar capillary
    • membrane.
    • c) Carriage of O2 & CO2
    • Internal respiration
    • Exchange of O2 & CO2 between blood & tissues.
  • 5. This achieved by :
    • (1) VENTILATION :
    • not only adequate in quantity ( minute ventilation is 4 liters) ,but be efficiently distributed to all perfused alveoli.
  • 6.
      • (2) PERFUSION :
    • Pulmonary capillary blood flow being delivered in adequate volume (5Liters/m) and distributed efficiently to all ventilated alveoli.
  • 7.
      • (3) DIFFUSION :
    • It is concerned with the volume of gas transferred across the alveolar capillary membrane.
    • When expressed in terms of time and unit difference in partial pressure of the gas (ml/min/mm Hg) is known as diffusing capacity.
  • 8. Factors affecting diffusion:
    • Pressure gradient of the gas.
    • Solubility of the gas.
    • Surface area of the pulmonary membrane.
    • Thickness of the pulmonary membrane.
    • Ventilation perfusion ratio.
  • 9.  
  • 10. Pulmonary function testing serves 2 important clinical goals:
    • (1) categorizing the physiologic impairment from lung disease (i.e., obstructive, restrictive, etc).
    • (2) quantifying the degree of functional impairment.
  • 11.
    • Spirometry :
    • The most common pulmonary function test.
    • It is quick, easy and non-invasive.
  • 12. The more common lung function values measured with spirometry are :
    • Forced vital capacity (FVC).
    • Forced expiratory volume (FEV).
    • Forced expiratory flow 25% to 75%.
    • Peak expiratory flow (PEF).
    • Maximum voluntary ventilation.
  • 13. Gas diffusion tests
    • Gas diffusion tests include :
    • Carbon monoxide diffusing capacity ,
    • Two different methods are used for this test. The single-breath or breath-holding method.
  • 14. Body plethysmography
    • Body plethysmography may be used to measure:
      • Total lung capacity (TLC).
      • Residual volume (RV) .
  • 15. Inhalation challenge tests
    • These tests are also called provocation studies.
    • Inhalation challenge tests are done to measure the response of airways to allergens that may be causing asthma.
  • 16. Exercise stress tests
    • Exercise stress tests evaluate the effect of exercise on lung function tests.
    • Spirometry readings are done after exercise and then again at rest.
  • 17.