TUMOR BOARD DISCUSSION
21.02.2014
Mrs. Panchavarnam
55/F
CA TONGUE – LAT.
1/3 rd
STAGE- cT3NOMO
HPE—Well diff. sq.
cell carcinoma
LOCALLY ADVANCED CA TONGUE
TREATMENT OF CHOICE
1. SURGERY→RT
2. RT→ SURGERY
3. CONCURRENT CHEMORT
4. NEO ADJUVANT CHEMO→CH...
LOCALLY ADVANCED CA TONGUE
SIGNS OF INOPERABILITY
1. POST 1/3 TONGUE INVOLMENT
2. MANDIBLE INVOLMENT
3. COSMETIC/ FUNCTION...
LOCALLY ADVANCED CA TONGUE
SURGERY
1. TRANSORAL
2. MANDIBULOTOMY
LOCALLY ADVANCED CA TONGUE
MANAGEMENT OF NECK
1. FOLLOW UP
2. RT
3. RADICAL NECK DISSECTION
LOCALLY ADVANCED CA TONGUE
NECK DISSECTION
1. RADICAL NECK DISSECTION
2. SELECTIVE NECK DISSECTION
3. SUPER SELECTIVE NECK...
LOCALLY ADVANCED CA TONGUE
RT
1. CONVENTIONAL RT
2. HYPERFRACTIONATED RT
3. ACCLERATED RT
LOCALLY ADVANCED CA TONGUE
RT TECHNIQUE
1. CONVENTIONAL
2. IMRT
3. PROTON THERAPY
LOCALLY ADVANCED CA TONGUE
CHEMO
1. PLATINUM BASED DOUBLETS
2. TPF
3. TPF⁺TARGETED AGENTS
LOCALLY ADVANCED CA TONGUE
EGFR DETECTION
1. IHC
2. OVER EXPRESSION
3. MUTATIONS
4. K RAS MUTATIONS
LOCALLY ADVANCED CA TONGUE
TARGETED AGENTS
1. CETUXIMAB
2. LAPATINIB
3. PANITUMUMAB
4. NIMOTUZUMAB
5. BEVACIZUMAB
6. EROLI...
LOCALLY ADVANCED CA TONGUE
HPV DETECTION
1. YES
2. NO
3. MAY BE
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
Tumor board discussion
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Tumor board discussion

  1. 1. TUMOR BOARD DISCUSSION 21.02.2014
  2. 2. Mrs. Panchavarnam 55/F CA TONGUE – LAT. 1/3 rd STAGE- cT3NOMO HPE—Well diff. sq. cell carcinoma
  3. 3. LOCALLY ADVANCED CA TONGUE TREATMENT OF CHOICE 1. SURGERY→RT 2. RT→ SURGERY 3. CONCURRENT CHEMORT 4. NEO ADJUVANT CHEMO→CHEMORT
  4. 4. LOCALLY ADVANCED CA TONGUE SIGNS OF INOPERABILITY 1. POST 1/3 TONGUE INVOLMENT 2. MANDIBLE INVOLMENT 3. COSMETIC/ FUNCTIONAL 4. ALL THE ABOVE
  5. 5. LOCALLY ADVANCED CA TONGUE SURGERY 1. TRANSORAL 2. MANDIBULOTOMY
  6. 6. LOCALLY ADVANCED CA TONGUE MANAGEMENT OF NECK 1. FOLLOW UP 2. RT 3. RADICAL NECK DISSECTION
  7. 7. LOCALLY ADVANCED CA TONGUE NECK DISSECTION 1. RADICAL NECK DISSECTION 2. SELECTIVE NECK DISSECTION 3. SUPER SELECTIVE NECK DISSECTION
  8. 8. LOCALLY ADVANCED CA TONGUE RT 1. CONVENTIONAL RT 2. HYPERFRACTIONATED RT 3. ACCLERATED RT
  9. 9. LOCALLY ADVANCED CA TONGUE RT TECHNIQUE 1. CONVENTIONAL 2. IMRT 3. PROTON THERAPY
  10. 10. LOCALLY ADVANCED CA TONGUE CHEMO 1. PLATINUM BASED DOUBLETS 2. TPF 3. TPF⁺TARGETED AGENTS
  11. 11. LOCALLY ADVANCED CA TONGUE EGFR DETECTION 1. IHC 2. OVER EXPRESSION 3. MUTATIONS 4. K RAS MUTATIONS
  12. 12. LOCALLY ADVANCED CA TONGUE TARGETED AGENTS 1. CETUXIMAB 2. LAPATINIB 3. PANITUMUMAB 4. NIMOTUZUMAB 5. BEVACIZUMAB 6. EROLITINIB 7. GEFTINIB
  13. 13. LOCALLY ADVANCED CA TONGUE HPV DETECTION 1. YES 2. NO 3. MAY BE

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