Neonatal EEG
Dr. Rahul Kumar
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
•
•
•
•

Activity discontinuous in early life
Long periods of electrical silence
Presen in both sleep and awake records
Se...
• EEG activity becomes continuous during
waking by 34 weeks CA
• EEG activity becomes continuous during
NREM by 37 weeks C...
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
• EEG activity asynchronous till 28 weeks CA
• Degree of asynchrony decreases with age,
mature brain has minimal asynchron...
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
• Beta-delta waveforms are composed of
random wave forms
• 0.3-1.5 Hz frequency, superimposed on fast
frequency
• Fast fre...
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
• Appear by 26 weeks CA
• 4.5-6 Hz, 20-200 µv
• Occur independently for short bursts, <2 sec
• Expressed maximally at 30-3...
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
• Bilaterally synchronous
• Present from 35 week CA, up to 44 weeks, till
6weeks post term
• 50-150 µv
• Resemble vertex s...
Parameter

Normal

Abnormal

Amplitude

50-150 µv

> 150 µv

Duration

<100 msec

>150 msec

Initial Polarity

Surface neg...
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
• Response easily identifiable by 37 weeks CA
• Generalised attenuation or rarely augmentation
of voltage to loud sounds s...
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
• Distinction clear by 36th week CA
• Till that age, Beta Delta complexes dominate
• These change to random, semi arrhythm...
Summary …
Road Map for the Session
•
•
•
•
•
•
•

Continuity
Inter-hemispheric Synchrony
Beta-Delta Complexes
Temporal Theta Bursts
...
Hypnagogic Hypersynchrony

Fp1-A1

Fp2-A2

C3-A1

C4-A2

O1-A1

O2-A2

T5-A1

T6-A2
50 µV
1 sec
Roffwarg, Muzio, and Dement. Science, 1966

34
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
Neonatal EEG Patterns
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Neonatal EEG Patterns

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This pattern discusses the various EEG patterns seen in term as well as pre term neonates. Normal Variations as well as pathological traces are discussed

Published in: Health & Medicine, Business
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Neonatal EEG Patterns

  1. 1. Neonatal EEG Dr. Rahul Kumar
  2. 2. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  3. 3. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  4. 4. • • • • Activity discontinuous in early life Long periods of electrical silence Presen in both sleep and awake records Seen till 30th week CA • This pattern is referred to as ‘Trace Discontinua’
  5. 5. • EEG activity becomes continuous during waking by 34 weeks CA • EEG activity becomes continuous during NREM by 37 weeks CA • However, semi-periodic, voltage attenuation still seen during NREM sleep, lasting for 1015 seconds • Present upto 5-6 weeks of age
  6. 6. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  7. 7. • EEG activity asynchronous till 28 weeks CA • Degree of asynchrony decreases with age, mature brain has minimal asynchrony
  8. 8. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  9. 9. • Beta-delta waveforms are composed of random wave forms • 0.3-1.5 Hz frequency, superimposed on fast frequency • Fast frequency in two frequency bands • 8-12 Hz and 18-22 Hz • Voltage <75 • Also known as spindle delta bursts, ripples of prematurity, etc
  10. 10. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  11. 11. • Appear by 26 weeks CA • 4.5-6 Hz, 20-200 µv • Occur independently for short bursts, <2 sec • Expressed maximally at 30-32 weeks CA, then decline in frequency • Used to determine CA, replaced by alpha rhythm
  12. 12. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  13. 13. • Bilaterally synchronous • Present from 35 week CA, up to 44 weeks, till 6weeks post term • 50-150 µv • Resemble vertex sharp waves
  14. 14. Parameter Normal Abnormal Amplitude 50-150 µv > 150 µv Duration <100 msec >150 msec Initial Polarity Surface negative Surface positive or negative Phase Mono or diphasic Polyphasic Occurrence Random, bilateral, Sleep Runs, 1Hz, unilateral, awake Following slow wave Absent Present
  15. 15. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  16. 16. • Response easily identifiable by 37 weeks CA • Generalised attenuation or rarely augmentation of voltage to loud sounds seen by 34 th week • If background is high voltage delta, response is attenuation • If background is low voltage theta, response is augmentation
  17. 17. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  18. 18. • Distinction clear by 36th week CA • Till that age, Beta Delta complexes dominate • These change to random, semi arrhythmic activity at 4-8 Hz • Trace alternans seen during 36-38 weeks
  19. 19. Summary …
  20. 20. Road Map for the Session • • • • • • • Continuity Inter-hemispheric Synchrony Beta-Delta Complexes Temporal Theta Bursts Frontal Sharp Waves Reactivity to Stimulus Differentiation between sleep and awake eeg
  21. 21. Hypnagogic Hypersynchrony Fp1-A1 Fp2-A2 C3-A1 C4-A2 O1-A1 O2-A2 T5-A1 T6-A2 50 µV 1 sec
  22. 22. Roffwarg, Muzio, and Dement. Science, 1966 34
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