P ROSTAGLANDINS PGL EUKOTRIENES LTTHROMBOXINE TXDR MUSTANSAR
INTRODUCTION Eicosanoids (20 carbons) are found in the animal kingdom and a variety of plants. The eicosanoids are oxygenation products of acid arachidonic (AA) polyunsaturated fatty acid. Acid arachidonic is released from membrane by phospholipase A2 (PLA2).
PROSTAGLANDINS & LEUKOTRIENES Localhormones - very active,many functions.. Autacoids from 20 C PUFA Prostaglandins Prostacyclin Thromboxanes Leukotrienes
FUNCTIONS Inflammation Smooth muscle tone Blood coagulation Reproduction GI secretion