Your SlideShare is downloading. ×
0
THE BILIARY TRACTLecture 30CHOLELITHIASIS
CholelithiasisPresence of stones in thegallbladder is referred to as cholelithiasis(from the Greekchol- (bile) +lith- (sto...
CHOLELITHIASIS (GALLSTONES)Epidemiology• Gallstones afflict 10% to 20% of adultpopulations in developed countries.• It is ...
TYPES OF GALLSTONES1.Cholesterol stones20%2.Pigment stones5%3.Mixed stones75%
The risk factors mostcommonly associated with the development ofcholesterol stones are:1. Age and Sex.2. Environmental Fac...
Cholesterol gallstone formation involves foursimultaneous conditions:(1) The bile must be supersaturated withcholesterol;(...
The four contributing factors for cholelithiasis: supersaturation, gallbladderhypomotility, crystal nucleation, and accret...
Clinical features
Clinical features• The vast majority ofgallstones (>80%) are“silent,” and mostindividuals remain free ofbiliary pain or ot...
SymptomsSymptoms commonly begin to appearonce the stones reach a certain size(>8 mm).
Pain during inspiration with examiner’s hand on theGB location.
"Is there any reward for good, other thangood?"
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
L30 gallstones student
Upcoming SlideShare
Loading in...5
×

L30 gallstones student

189

Published on

Published in: Health & Medicine, Business
0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
189
On Slideshare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
22
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide

Transcript of "L30 gallstones student"

  1. 1. THE BILIARY TRACTLecture 30CHOLELITHIASIS
  2. 2. CholelithiasisPresence of stones in thegallbladder is referred to as cholelithiasis(from the Greekchol- (bile) +lith- (stone) +iasis- (process).
  3. 3. CHOLELITHIASIS (GALLSTONES)Epidemiology• Gallstones afflict 10% to 20% of adultpopulations in developed countries.• It is estimated that more than 20 million personsin the United States have gallstones, totaling some25 to 50 tons in weight!Over 95% of biliary tract disease isattributable tocholelithiasis (gallstones).
  4. 4. TYPES OF GALLSTONES1.Cholesterol stones20%2.Pigment stones5%3.Mixed stones75%
  5. 5. The risk factors mostcommonly associated with the development ofcholesterol stones are:1. Age and Sex.2. Environmental Factors.3. Acquired Disorders.4. Hereditary Factors.
  6. 6. Cholesterol gallstone formation involves foursimultaneous conditions:(1) The bile must be supersaturated withcholesterol;(2) hypomotility of the gallbladder promotesnucleation;(3) cholesterol nucleation in the bile isaccelerated;(4) hypersecretion of mucus in the gallbladdertraps the nucleated crystals, leading to theiraggregation into stones.Accretion within the gallbladder mucous layer.
  7. 7. The four contributing factors for cholelithiasis: supersaturation, gallbladderhypomotility, crystal nucleation, and accretion within the gallbladder mucous layer.Amicelleis anaggregate ofsurfactantmoleculesdispersed inaliquidcolloid12 34
  8. 8. Clinical features
  9. 9. Clinical features• The vast majority ofgallstones (>80%) are“silent,” and mostindividuals remain free ofbiliary pain or othercomplications for
  10. 10. SymptomsSymptoms commonly begin to appearonce the stones reach a certain size(>8 mm).
  11. 11. Pain during inspiration with examiner’s hand on theGB location.
  12. 12. "Is there any reward for good, other thangood?"
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×