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Dr. Muhammad Ayub, FCPS
       Diplomate Certification Board of Nuclear Cardiology
   Diplomate Board of Cardiovascular Computed Tomography
 Department of Cardiovascular Imaging
Punjab Institute of Cardiology Lahore
Cardiac CT
Technical considerations
 Spatial Resolution       0.4mm
 Temporal Resolution      85ms-200ms
 Contrast                 70-100ml
 Radiation                6-13 msv
Cardiovascular CT
+
 Noninvasive
 Fast
 Calcium Scoring
 3D anatomic information
 Can see beyond lumen (atheroma imaging)
Cardiovascular CT
_
 Contrast
 Radiation
 Limited spatial resolution
 Limited Temporal Resolution(Requires slow heart rate)
 No hemodynamic information
 Technical Artifacts
 Limitation in patients with high coronary calcium
Types of studies
 Without contrast (Calcium Scoring)
 Contrast studies (CT Angiography)
Calcium Scoring
Coronary Calcium Scoring
CT Coronary Angiography
Appropriateness Criteria
Pre test Probability for CAD
Low Probability (<10%)
  Asymptomatic men and women of all ages
  Women < 50 years with atypical chest pain

Intermediate Probability (10%-90%)
  Men of all ages with atypical angina
  Women ≥ 50 years with atypical angina
  Women 30-50 years with typical angina

High Probability
  Men ≥ 40 years with typical angina
  Women ≥ 50 years with typical angina
CT Angiography:
Appropriate Indications (Median Score 7–9)


 Detection of CAD:

   Symptomatic—Evaluation of Chest Pain Syndrome      Score

   Intermediate pre-test probability of CAD.

        ECG un-interpretable OR unable to exercise.   A (8)

        ECG interpretable and able to exercise.       A (7)

   Low pre-test probability of CAD.

        ECG un-interpretable OR unable to exercise.   A (7)
Normal CT Angiogram
51 year old male with atypical chest pain
Appropriate?
       • 40 year male
       • Smoker, FH
       • Atypical chest pain




Appropriateness Criteria
Intermediate pre-test probability of CAD
ECG interpretable and able to exercise. A (7)
Appropriate?
   49 years old male
   No risk factors
   BMI of 26 m/Kg
   presented with new onset
      angina FC II-III




Appropriateness Criteria
High pre-test probability of CAD
ECG interpretable and able to exercise.      I (3)
ECG un-interpretable and able to exercise.   U (4)
CCA confirmed the lesion PCI
of LAD with Cypher
kissing Balloon angioplasty of
Diagonal was done
Appropriate indications
 35 year old male non smoker Hypertensive with occasional H/O post prandial chest pain
 has had his ETT which was equivocal. CT Angio showed Normal Coronaries




                            Appropriateness Criteria
                            Diagnosis of Chest Pain
                            Equivocal stress test                                   A(8)
Evaluation of suspected coronary anomalies
 50 years old male had CCA for
  angina FC III but could not
  engage RCA
 Referred for CT Angio for exact
  localization and lesion of RCA



 CT Angio showed
 Anomalous origin of RCA from
  LCC



  Appropriateness Criteria
  Detection of CAD:
  Symptomatic—Evaluation of Intra-Cardiac Structures
         Evaluation of suspected coronary anomalies A (9)
Evaluation of suspected coronary anomalies
 21 years old female
 SOB FC II
 Continuous murmur at base
 Normal Dimensions of LV and RV
 Continuous flow at LCC on CWD




Appropriateness Criteria
Detection of CAD:
Symptomatic—Evaluation of Intra-Cardiac Structures
       Evaluation of suspected coronary anomalies A (9)
48 year male with typical chest pain:
Suspected coronary anomaly on conventional angiogram




                                    Appropriateness Criteria
                                    Detection of CAD:
                                    Symptomatic—Evaluation of Intra-Cardiac Structures
                                           Evaluation of suspected coronary anomalies A (9)
Young girl following VSD repair:
Suspected Coronary Fistula into RVOT




                               Appropriateness Criteria
                               Detection of CAD:
                               Symptomatic—Evaluation of Intra-Cardiac Structures
                                      Evaluation of suspected coronary anomalies A (9)
35 year old male smoker Hypertensive with acute chest pain
CT Angio showed Normal Coronaries




             Appropriateness Criteria
             Detection of CAD: Symptomatic—Acute Chest PainIntermediate pre-test probability of CAD. No
             ECG changes and serial enzymes negative                                          A (7)
Assessment of Cardiac Masses
 48 year old male
 Known Case of AS
 Suspected Atrial mass, not
  clearly visualized on echo




              Appropriateness Criteria
              Structure and Function—Evaluation of Intra- and Extra-Cardiac StructuresEvaluation of
              cardiac mass (suspected tumor or thrombus). Patients with technically limited images
              from echocardiogram, MRI, or TEE                                                 A (8)
AS, Myxoma
Assessment of Pericardial Conditions




  Appropriateness Criteria
  Evaluation of pericardial conditions (pericardial mass, constrictive pericarditis, or complications of cardiac surgery).
  Patients with technically limited images from echocardiogram, MRI, or TEE                                         A (8)
Assessment of Pulmonary Venous Anatomy




Appropriateness criteria
Evaluation of pulmonary vein anatomy prior to invasive radiofrequency ablation for atrial fibrillation   A (8)
Assessment of Pulmonary Veins prior to
biventricular pacemaker




    Appropriateness Criteria
    Noninvasive coronary vein mapping prior to placement of biventricular pacemaker   A (8)
Post CABG Assessment




Appropriateness Criteria
Assessment of graft patency in symptomatic patients                                                                      A (8)
Noninvasive coronary arterial mapping, including internal mammary artery prior to repeat cardiac surgical revascularization A (8)
Assessment of Aorta




Appropriateness Criteria
Structure and Function—Evaluation of Aortic and Pulmonary Disease
Evaluation of suspected aortic dissection or thoracic aortic aneurysm A (9)
Aortic Dissection




Appropriateness Criteria
Structure and Function—Evaluation of Aortic and Pulmonary Disease
Evaluation of suspected aortic dissection or thoracic aortic aneurysm   A (9)
Aortic Dissection
Aortic Study
  Total Occlusion




Appropriateness Criteria
Structure and Function—Evaluation of Aortic and Pulmonary Disease
Evaluation of suspected aortic dissection or thoracic aortic aneurysm   A (9)
Congenital Heart Disease
Aortic Coarctation
Interrupted Arch
Suspected Aortitis
Assessment of Pulmonary vessels




Appropriateness Criteria
Structure and Function—Evaluation of Aortic and Pulmonary Disease
Evaluation of suspected pulm embolism                               A (9)
Assessment of Congenital Heart Disease




   Appropriateness Criteria
   Assessment of Complex Congenital Heart Disease including anomalies of coronaries, great vessels, cardiac
   chambers and Valves                                                                            A(7)
Assessment of Complex Congenital Heart Disease




                                                                                        ASD
          VSD


      Appropriateness Criteria
      Assessment of Complex Congenital Heart Disease including anomalies of coronaries, great vessels,
      cardiac chambers and Valves                                                                A(7)
Assessment of Complex Congenital Heart Disease
SV ASD + PAPVD




     Appropriateness Criteria
     Assessment of Complex Congenital Heart Disease including anomalies of coronaries, great vessels, cardiac
         chambers and Valves                                                                        A(7)
Interrupted Arch
Congenital Heart Disease
Assessment of cardiac function




Appropriateness Criteria
   Evaluation of left ventricular function
   ● Following acute MI or in HF patients
   ● Inadequate images from other noninvasive methods   A (7)
Assessment of Cardiac Valves




                Appropriateness Criteria
                Characterization of native cardiac valves
                ● Suspected clinically significant valvular dysfunction
                ● Inadequate images from other noninvasive methods        A (8)
Assessment of prosthetic Valves




       Appropriateness Criteria
       Characterization of prosthetic cardiac valves
       ● Suspected clinically significant valvular dysfunction
       ● Inadequate images from other noninvasive methods        A (8)
Uncertain Indications




                                               Patent
                                               Stent



                        Assessment of stents    U(5)
CTA Limitations
  Rapid (>80 bpm) and irregular HR
  High calcium scores (>800-1000)
  Stents
  Contrast requirements (Cr > 2.0 mg/dl)
  Small vessels (<1.5 mm) and collaterals
  Obese and uncooperative patients
  RADIATION EXPOSURE
Thank you

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Clinical Applications Of Cardiac Ct

  • 1. Dr. Muhammad Ayub, FCPS Diplomate Certification Board of Nuclear Cardiology Diplomate Board of Cardiovascular Computed Tomography Department of Cardiovascular Imaging Punjab Institute of Cardiology Lahore
  • 2. Cardiac CT Technical considerations  Spatial Resolution 0.4mm  Temporal Resolution 85ms-200ms  Contrast 70-100ml  Radiation 6-13 msv
  • 3. Cardiovascular CT +  Noninvasive  Fast  Calcium Scoring  3D anatomic information  Can see beyond lumen (atheroma imaging)
  • 4. Cardiovascular CT _  Contrast  Radiation  Limited spatial resolution  Limited Temporal Resolution(Requires slow heart rate)  No hemodynamic information  Technical Artifacts  Limitation in patients with high coronary calcium
  • 5. Types of studies  Without contrast (Calcium Scoring)  Contrast studies (CT Angiography)
  • 10. Pre test Probability for CAD Low Probability (<10%) Asymptomatic men and women of all ages Women < 50 years with atypical chest pain Intermediate Probability (10%-90%) Men of all ages with atypical angina Women ≥ 50 years with atypical angina Women 30-50 years with typical angina High Probability Men ≥ 40 years with typical angina Women ≥ 50 years with typical angina
  • 11. CT Angiography: Appropriate Indications (Median Score 7–9)  Detection of CAD: Symptomatic—Evaluation of Chest Pain Syndrome Score Intermediate pre-test probability of CAD. ECG un-interpretable OR unable to exercise. A (8) ECG interpretable and able to exercise. A (7) Low pre-test probability of CAD. ECG un-interpretable OR unable to exercise. A (7)
  • 13. 51 year old male with atypical chest pain
  • 14. Appropriate? • 40 year male • Smoker, FH • Atypical chest pain Appropriateness Criteria Intermediate pre-test probability of CAD ECG interpretable and able to exercise. A (7)
  • 15. Appropriate?  49 years old male  No risk factors  BMI of 26 m/Kg  presented with new onset angina FC II-III Appropriateness Criteria High pre-test probability of CAD ECG interpretable and able to exercise. I (3) ECG un-interpretable and able to exercise. U (4)
  • 16. CCA confirmed the lesion PCI of LAD with Cypher kissing Balloon angioplasty of Diagonal was done
  • 17. Appropriate indications 35 year old male non smoker Hypertensive with occasional H/O post prandial chest pain has had his ETT which was equivocal. CT Angio showed Normal Coronaries Appropriateness Criteria Diagnosis of Chest Pain Equivocal stress test A(8)
  • 18. Evaluation of suspected coronary anomalies  50 years old male had CCA for angina FC III but could not engage RCA  Referred for CT Angio for exact localization and lesion of RCA  CT Angio showed  Anomalous origin of RCA from LCC Appropriateness Criteria Detection of CAD: Symptomatic—Evaluation of Intra-Cardiac Structures Evaluation of suspected coronary anomalies A (9)
  • 19. Evaluation of suspected coronary anomalies  21 years old female  SOB FC II  Continuous murmur at base  Normal Dimensions of LV and RV  Continuous flow at LCC on CWD Appropriateness Criteria Detection of CAD: Symptomatic—Evaluation of Intra-Cardiac Structures Evaluation of suspected coronary anomalies A (9)
  • 20. 48 year male with typical chest pain: Suspected coronary anomaly on conventional angiogram Appropriateness Criteria Detection of CAD: Symptomatic—Evaluation of Intra-Cardiac Structures Evaluation of suspected coronary anomalies A (9)
  • 21. Young girl following VSD repair: Suspected Coronary Fistula into RVOT Appropriateness Criteria Detection of CAD: Symptomatic—Evaluation of Intra-Cardiac Structures Evaluation of suspected coronary anomalies A (9)
  • 22. 35 year old male smoker Hypertensive with acute chest pain CT Angio showed Normal Coronaries Appropriateness Criteria Detection of CAD: Symptomatic—Acute Chest PainIntermediate pre-test probability of CAD. No ECG changes and serial enzymes negative A (7)
  • 23. Assessment of Cardiac Masses  48 year old male  Known Case of AS  Suspected Atrial mass, not clearly visualized on echo Appropriateness Criteria Structure and Function—Evaluation of Intra- and Extra-Cardiac StructuresEvaluation of cardiac mass (suspected tumor or thrombus). Patients with technically limited images from echocardiogram, MRI, or TEE A (8)
  • 25. Assessment of Pericardial Conditions Appropriateness Criteria Evaluation of pericardial conditions (pericardial mass, constrictive pericarditis, or complications of cardiac surgery). Patients with technically limited images from echocardiogram, MRI, or TEE A (8)
  • 26. Assessment of Pulmonary Venous Anatomy Appropriateness criteria Evaluation of pulmonary vein anatomy prior to invasive radiofrequency ablation for atrial fibrillation A (8)
  • 27. Assessment of Pulmonary Veins prior to biventricular pacemaker Appropriateness Criteria Noninvasive coronary vein mapping prior to placement of biventricular pacemaker A (8)
  • 28. Post CABG Assessment Appropriateness Criteria Assessment of graft patency in symptomatic patients A (8) Noninvasive coronary arterial mapping, including internal mammary artery prior to repeat cardiac surgical revascularization A (8)
  • 29. Assessment of Aorta Appropriateness Criteria Structure and Function—Evaluation of Aortic and Pulmonary Disease Evaluation of suspected aortic dissection or thoracic aortic aneurysm A (9)
  • 30. Aortic Dissection Appropriateness Criteria Structure and Function—Evaluation of Aortic and Pulmonary Disease Evaluation of suspected aortic dissection or thoracic aortic aneurysm A (9)
  • 32. Aortic Study Total Occlusion Appropriateness Criteria Structure and Function—Evaluation of Aortic and Pulmonary Disease Evaluation of suspected aortic dissection or thoracic aortic aneurysm A (9)
  • 36. Assessment of Pulmonary vessels Appropriateness Criteria Structure and Function—Evaluation of Aortic and Pulmonary Disease Evaluation of suspected pulm embolism A (9)
  • 37. Assessment of Congenital Heart Disease Appropriateness Criteria Assessment of Complex Congenital Heart Disease including anomalies of coronaries, great vessels, cardiac chambers and Valves A(7)
  • 38. Assessment of Complex Congenital Heart Disease ASD VSD Appropriateness Criteria Assessment of Complex Congenital Heart Disease including anomalies of coronaries, great vessels, cardiac chambers and Valves A(7)
  • 39. Assessment of Complex Congenital Heart Disease SV ASD + PAPVD Appropriateness Criteria Assessment of Complex Congenital Heart Disease including anomalies of coronaries, great vessels, cardiac chambers and Valves A(7)
  • 42. Assessment of cardiac function Appropriateness Criteria  Evaluation of left ventricular function  ● Following acute MI or in HF patients  ● Inadequate images from other noninvasive methods A (7)
  • 43. Assessment of Cardiac Valves Appropriateness Criteria Characterization of native cardiac valves ● Suspected clinically significant valvular dysfunction ● Inadequate images from other noninvasive methods A (8)
  • 44. Assessment of prosthetic Valves Appropriateness Criteria Characterization of prosthetic cardiac valves ● Suspected clinically significant valvular dysfunction ● Inadequate images from other noninvasive methods A (8)
  • 45. Uncertain Indications Patent Stent Assessment of stents U(5)
  • 46. CTA Limitations  Rapid (>80 bpm) and irregular HR  High calcium scores (>800-1000)  Stents  Contrast requirements (Cr > 2.0 mg/dl)  Small vessels (<1.5 mm) and collaterals  Obese and uncooperative patients  RADIATION EXPOSURE