Currently, the lung cancer death rate in women is about two-and-a-half times what it was 25 years ago, and lung cancer is the most common cause of cancer death. In comparison, breast cancer death rates were virtually unchanged between 1930 and 1990, and have since decreased. The death rates for stomach and uterine cancers have decreased steadily since 1930; colorectal cancer death rates have been decreasing for over 50 years.
The next four slides look at the lifetime probability of developing cancer and relative survival rates of cancer. Presently, the risk of an American man developing cancer over his lifetime is one in two. The leading cancer sites are prostate, lung, and colon & rectum.
Cancer Dr. G.S. Jogdand, M.D. Ph.D. Professor & Head Community Medicine Department
Tumor Markers Name Foetal Ag Normally detected Tumor Carcion Embryonic Antigen yes yes GIT, Lung, Breast Cancer Ag. 125 yes yes Ovary Alpha fetoprotein yes yes Hepato-cellular Ca, germ cell tumors Lactate dehydrogenase No yes Most reflecting tumor burden Prostate specific Antigen No Yes Prostate cancer Human Chorionic Gonadotrophin No Pregnancy Teratoma, chorio-carcinoma
Problem statement: Incidence and mortality of cancer (Global)
Site Incidence Mortality
Male Female Male Female
Lung 901 337 810 292
Breast - 1050 - 372
Colo 498 445 254 237
Stomach 558 317 405 241
Liver 398 165 383 164
Five leading cancers their gender wise incidence & mortality, per lakh population.
Cancer Death Rates, for Women *Age-adjusted to the 2000 US standard population. Source: US Mortality Public Use Data Tapes 1960-2000, US Mortality Volumes 1930-1959, National Center for Health Statistics, Centers for Disease Control and Prevention, 2003. Lung Colon & rectum Uterus Stomach Breast Ovary Pancreas Rate Per 100,000
Lifetime Probability of Developing Cancer, Men, US, 1998-2000 Source: DevCan: Probability of Developing or Dying of Cancer Software, Version 5.1 Statistical Research and Applications Branch, NCI, 2003. http://srab.cancer.gov/devcan All sites 1 in 2 Cancer