The UsefulChem Project: An Application of Open Source Science in Malaria Research Jean-Claude Bradley PhD, Khalid Mirza, James Giammarco, Dave Strumfels, Lin Cheng usefulchem.wikispaces.com usefulchem.blogspot.com
We describe the development of UsefulChem, an open source science project using blogs and wikis to make the scientific process as transparent as possible. Blogs are used to provide RSS information feeds on experimental details, molecules of interest to the projects, and the thinking process behind the design and evaluation of synthetic strategies. Visitors to the site are able to comment freely on the progress of the experiments as well as offer solutions to any obstacles that may arise.
This method was applied to a malaria project in which we are synthesizing diketopiperazine derivatives that have been proposed as candidates for inhibition of enyol reductase, an enzyme required for the malarial parasite to propagate.
Open science connectivity More info on open source science here http://usefulchem.wikispaces.com