The Toxicology and Environmental Health Information Program (TEHIP) evolved from the Toxicology Information Program (TIP) that was established in 1967 at the National Library of Medicine (NLM) in response to recommendations made in the 1966 report &quot;Handling of Toxicological Information,&quot; prepared by the President's Science Advisory Committee. The TIP objectives were to: (1) create automated toxicology data banks, and (2) provide toxicology information and data services. In the mid-1990's, the mission of TIP was expanded to include environmental health. TEHIP, by creating, organizing, and disseminating toxicology and environmental health information, now serves as a premier information portal for resources in these subject areas. TEHIP maintains a comprehensive toxicology and environmental health web site that includes access to resources produced by TEHIP and by other government agencies and organizations. This web site includes links to databases, bibliographies, tutorials, and other scientific and consumer-oriented resources. TEHIP also is responsible for the Toxicology Data Network (TOXNET®), an integrated system of toxicology and environmental health databases that are available free of charge on the web. The following databases are available for searching via TOXNET:
Vaccine Benefits, Risks, Alternatives and the Florida Law David Berger, MD Medical Director Wholistic Pediatrics Tampa, FL (813) 960-3415 www.wholisticpeds.com
Are we unnaturally stressing underdeveloped immune systems beyond their capabilities in our effort to keep the children from contracting an infection?
Are we giving too many vaccines too early in life or over a short time span (ex: <2 month olds with fever)?
There are inadequate safety studies that have looked beyond the immediate period after vaccination. This is especially so when vaccines are given in combinations.
There are inadequate safety studies that look at subgroups of people, such as those with family history of autoimmune and hyper inflammatory conditions
We do not have a clear understanding of the effects of some of the vaccine components such as Thimerosal, aluminum, formaldehyde, and human fetal tissue. Nor do we understand how they interact with atypical immune systems and toxins that people are more commonly being exposed to.
(to consider: 6 months for food introduction, and 1 at a time)
“ The developing fetus and young children are thought to be disproportionately affected by mercury exposure, because many aspects of development, particularly brain maturation, can be disturbed by the presence of mercury. Minimizing mercury exposure is, therefore, essential to optimal child health ….. Mercury in all of its forms is toxic to the fetus and children , and efforts should be made to reduce exposure to the extent possible to pregnant women and children as well as the general population .” MERCURY Statement: Pediatrics 2001 Jul, American Academy of Pediatrics: Committee on Environmental Health.
Vaccine inserts would typically say “0.01% thimerosal as a preservative”, which to anyone would sound like an extremely small amount. When called to testify in front of the Institute of Medicine, an independent group formed by our government to monitor safety issues, Dr. Neil Halsey of Johns Hopkins University and head of the vaccine recommendation committee that reports to the CDC, went on record as saying “ No one ever did the math…. No one knows what dose of mercury, if any, from vaccines is safe. We can say there is no evidence of harm but the truth is no one has looked ” Thimerosal/Mercury in Vaccines
Type Name Manufacturer mcg mercury DTaP Tripedia Sanofi Pasteur ≤0.3 DT No Name (single) Sanofi Pasteur ≤0.3 DT No Name (multi ) Sanofi Pasteur 25 Td No Name Mass Public Health 8.3 Td Decavac Sanofi Pasteur ≤0.3 TT No Name Sanofi Pasteur 25 Hep A/B Twinrix GlaxoSmithKline ≤1 Influenza Afluria multi dose CSL 24.5 Influenza Fluzone –Full dose for 3y) Sanofi Pasteur 25 Influenza Fluzone – ½ dose < 3y/o) Sanofi Pasteur 25 Influenza Fluvirin Novartis 25 Influenza Fluvirin (Prsv Free) Novartis ≤1 Influenza Fluarix GlaxoSmithKline ≤1 Influenza FluLaval ID Biomedical 25 Jap Enceph. JE-VAX Osaka Univ. 17.5 -35 Meningococus Menomune (multidose) Sanofi Pasteur 25 Updated full table maintained in “Vaccine” Section at www.wholisticpeds.com Previous tables dating back to 2000 are also presented. Vaccines that Still Contain Mercury
On average, for each 1000 lb of environmentally released mercury, there was a 43% increase in the rate of special education services and a 61% increase in the rate of autism. Palmer et al. Health & Place 12 (2006) 203–209 Total toxicity Autism rates Proximity to point sources of environmental mercury release as a predictor of autism prevalence. Palmer et al. Health & Place 2008
Int J Audiol. 2008 Dec;47(12):770-6, Rothwell JA , Boyd PJ . Audiology Department, General Hospital, St. Helier, Jersey, Channel Islands.
In this study we investigated the effects of amalgam dental fillings on auditory
thresholds . Participants (n=39) were non-smoking women age 40 to 45.
Regression and correlation analyses were performed between auditory thresholds,
measured from 0.25 to 16 kHz, and the number/surface area of dental fillings,
using the ASHA criteria for ototoxic change as a reference for comparison. No
significant correlation (p>0.05) was found between composite (non-amalgam)
filling or drilling data and auditory thresholds. However, there was a significant
positive linear correlation between amalgam filling data and auditory thresholds at
8, 11.2, 12.5, 14, and 16 kHz. The strongest association (r=0.587, n=39, p<.001,
r(2)=0.345) was at 14 kHz, where each additional amalgam filling was associated
with a 2.4 dB decline in hearing threshold (95% confidence interval [CI], 1.3-3.5
The results suggest an association between more amalgam fillings and poorer thresholds at higher frequencies, which could contribute to presbyacusis in developed countries. This provides further argument for the use of amalgams to be phased out where suitable alternatives exist.
Children with Autism are Prone to Decreased Ability to Detoxify
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
James SJ , Cutler P , Melnyk S , Jernigan S , Janak L , Gaylor DW , Neubrander JA .
Department of Pediatrics, University of Arkansas for Medical Sciences
Am J Clin Nutr. 2004 Dec;80(6):1611-7
BACKGROUND: Autism is a complex neurodevelopmental disorder that usually presents in early childhood and that is thought to be influenced by genetic and environmental factors. Although abnormal metabolism of methionine and homocysteine has been associated with other neurologic diseases, these pathways have not been evaluated in persons with autism. OBJECTIVE: The purpose of this study was to evaluate plasma concentrations of metabolites in the methionine transmethylation and transsulfuration pathways in children diagnosed with autism. DESIGN: Plasma concentrations of methionine, S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), adenosine, homocysteine, cystathionine, cysteine, and oxidized and reduced glutathione were measured in 20 children with autism and in 33 control children. On the basis of the abnormal metabolic profile, a targeted nutritional intervention trial with folinic acid, betaine, and methylcobalamin was initiated in a subset of the autistic children. RESULTS: Relative to the control children, the children with autism had significantly lower baseline plasma concentrations of methionine, SAM, homocysteine, cystathionine, cysteine, and total glutathione and significantly higher concentrations of SAH, adenosine, and oxidized glutathione. This metabolic profile is consistent with impaired capacity for methylation (significantly lower ratio of SAM to SAH) and increased oxidative stress (significantly lower redox ratio of reduced glutathione to oxidized glutathione) in children with autism. The intervention trial was effective in normalizing the metabolic imbalance in the autistic children. CONCLUSIONS : An increased vulnerability to oxidative stress and a decreased capacity for methylation may contribute to the development and clinical manifestation of autism.
After exposure to mercury, the length of time to be eliminated varies for different organs:
Blood and Hair: 4-6 months
Non Central Nervous System organs: several years
Brain: 20 years
(Boyd Haley, PhD, University of Kentucky, Dept of Chemistry)
Lead typically deposits into brain and bone. After exposure to lead, within several months the blood and urine levels will be normal even if the lead is still in the bone and brain (Clarkson, 2002)
Some Children with Autism Do Not Clear Mercury Mercury in first-cut baby hair of children with autism versus typically-developing children J. B. Adams; J. Romdalvik; K. E. Levine; Lin-Wen Hu (Arizona State University) Toxicological & Environmental Chemistry , May 2, 2008 Children with autism were examined to determine amounts of mercury (Hg) in their baby hair and the factors that might affect Hg body burden. US children with autism (n = 78) and matched controls (n = 31) born between 1988 and 1999 were studied . Hg in first-cut baby hair was determined using cold vapor atomic fluorescence spectrometry (CVAFS). Twenty samples were split and also measured with Neutron Activation Analysis (NAA). Logistic regression analysis showed that compared to children with higher levels of mercury (above 0.55 mcg g-1), children with lower levels of mercury in their hair (below 0.55 mcg g-1) were 2.5-fold more likely to manifest with autism . Children with autism had similar mercury exposure as controls from maternal seafood and maternal dental amalgams. Children with autism also had 2.5-fold higher incidence of oral antibiotic use during their first 18 months of life. Their mothers were possibly more likely to use oral antibiotics during pregnancy or nursing. The amount of Hg in the baby hair of children with autism showed a significant correlation with the number of maternal dental amalgams. The lower level of Hg in the baby hair of children with autism indicates an altered metabolism of Hg, and may be due to a decreased ability to excrete Hg. This is consistent with usage of higher amounts of oral antibiotics, which are known to inhibit Hg excretion in rats due to alteration of gut flora, and may exert a similar effect in humans. Higher usage of oral antibiotics in infancy may also partially explain the high incidence of chronic gastrointestinal problems seen in individuals with autism.
“ According to the concession report, this case involved a toddler who was developing normally until 18 months of age. Several days after the 18 month shots her development began to decline to the point that she eventually displayed many features of autism. Doctors also discovered that the child had a mitochondrial disorder (a disorder of metabolism that makes a child pre-disposed to developmental and medical problems). The court decided that there was enough evidence to show that the vaccines may have aggravated the mitochondrial disorder and triggered problems consistent with autistic-like behavior.”
Dr Robert Sears, Author of “The Vaccine Book: Making the right decision for your child”
“ Many early childhood vaccinations have been viewed as promoters of asthma development by stimulating a Th2-type immune response, shifting the cytokine balance” (Johnston, et al, 2002)
“ At birth the newborn immune system has a limited ability to produce Th1 cytokines but levels increase over the period of the next 6 months” (Marodi, 2002)
CONCLUSION: We found a negative association between delay in administration of the first dose of whole-cell DPT immunization in childhood and the development of asthma; the association was greater with delays in all of the first 3 doses. The mechanism for this phenomenon requires further research.
Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma
Vaccine Induced Autoimmunity (Cohen&Shoenfeld, Tel Aviv University, Journal of Autoimmunity , 1996)
Hepatitis B vaccine and the risk of CNS inflammatory demyelination in childhood
Yann Mikaeloff, MD, PhD, Guillaume Caridade, MSc, Samy Suissa, PhD and Marc Tardieu, MD, Ph
FromAssistance Publique-Hôpitaux de Paris and Division of Clinical Epidemiology (S.S.), McGill University and Royal Victoria Hospital, Montreal, Canada.
Background: The risk of CNS inflammatory demyelination associated with hepatitis B (HB) vaccine is debated, with studies reporting conflicting findings.
Methods: We conducted a population-based case-control study where the cases were children with a first episode of acute CNS inflammatory demyelination in France (1994–2003). Each case was matched on age, sex, and geographic location to up to 12 controls, randomly selected from the general population. Information on vaccinations was confirmed by a copy of the vaccination certificate. The odds ratios (ORs) of CNS inflammatory demyelination associated with HB vaccination were estimated using conditional logistic regression.
Results: The rates of HB vaccination in the 3 years before the index date were 24.4% for the 349 cases and 27.3% for their 2,941 matched controls. HB vaccination within this period was not associated with an increase in the rate of CNS inflammatory demyelination (adjusted OR, 0.74; 0.54–1.02), neither >3 years nor as a function of the number of injections or brand type. When the analysis was restricted to subjects compliant with vaccination, HB vaccine exposure >3 years before index date was associated with an increased trend (1.50; 0.93–2.43), essentially from the Engerix B vaccine (1.74; 1.03–2.95). The OR was particularly elevated for this brand in patients with confirmed multiple sclerosis (2.77; 1.23–6.24).
Conclusions: Hepatitis B vaccination does not generally increase the risk of CNS inflammatory demyelination in childhood. However, the Engerix B vaccine appears to increase this risk, particularly for confirmed multiple sclerosis, in the longer term. Our results require confirmation in future studies
IL-12 Down-Regulates Autoantibody Production in Mercury-Induced Autoimmunity
Lee M. Bagenstose, Padmini Salgame 2 and Marc Monestier 2
Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA
In genetically susceptible H-2 s mice, subtoxic doses of mercuric chloride (HgCl 2 ) induce a complex autoimmune syndrome characterized by the production of anti-nucleolar IgG Abs, lymphoproliferation, increased serum levels of IgG1 and IgE Abs, and renal Ig deposits. Mercury-induced autoimmunity in H-2 s mice provides a useful model for chemically related autoimmunity in humans . The increase in serum IgG1 and IgE, which are under IL-4 control, suggests a role for the Th2 subset in this syndrome . The IL-12 cytokine induces T cell proliferation and IFN- production and is necessary for differentiation of naive T cells into the Th1 subset. To gain an understanding of T cell control in this syndrome and, in particular, Th1/Th2 regulation, we assessed the effect of IL-12 administration in mercury-induced autoimmunity. Groups of A.SW mice (H-2 s ) received HgCl 2 plus IL-12, HgCl 2 alone, or IL-12 alone. IL-12 treatment resulted in a dramatic reduction of the anti-nucleolar Ab titers. IL-12 also inhibited the HgCl 2 -induced serum IgG1 increase, but, in contrast, did not significantly affect IgE induction in this model. This observation may be related to our unexpected finding that IL-12 further potentiated the HgCl 2 -triggered IL-4 induction in this model. The levels of renal Ig deposits were similar in mice receiving HgCl 2 alone or HgCl 2 plus IL-12. Our results indicate that IL-12 can down-regulate the autoimmune component of this experimental syndrome and that the various manifestations of mercury-induced autoimmunity are independently regulated.
Children with Autism are prone to autoimmunity
Prevalence of serum antibodies to caudate nucleus in autistic children
Vijendra K. Singh , and Wyatt H. Rivas
Department of Biology, Biotechnology Center Building, Utah State University
Neuroscience Letters, October 2003
Autism may involve autoimmunity to brain. We studied regional distribution of antibodies to rat caudate nucleus, cerebral cortex, cerebellum, brain stem and hippocampus. The study included 30 normal and 68 autistic children. Antibodies were assayed by immunoblotting. Autistic children, but not normal children, had antibodies to caudate nucleus (49% positive sera), cerebral cortex (18% positive sera) and cerebellum (9% positive sera). Brain stem and hippocampus were negative. Antibodies to caudate nucleus were directed towards three proteins having 160, 115 and 49 kD molecular weights. Since a significant number of autistic children had antibodies to caudate nucleus, we propose that an autoimmune reaction to this brain region may cause neurological impairments in autistic children. Thus, the caudate nucleus might be involved in the neurobiology of autism.
Children with Autism are prone to autoimmunity
Abnormal Measles-Mumps-Rubella Antibodies and CNS Autoimmunity in Children with Autism
Vijendra K. Singh, Sheren X. Lin, Elizabeth Newell, Courtney Nelson Department of Biology and Biotechnology Center, Utah State University, Logan, Utah, USA Journal of Biomedical Science 9:4:2002, 359-364. Autoimmunity to the central nervous system (CNS), especially to myelin basic protein (MBP), may play a causal role in autism, a neurodevelopmental disorder. Because many autistic children harbor elevated levels of measles antibodies, we conducted a serological study of measles-mumps-rubella (MMR) and MBP autoantibodies. Using serum samples of 125 autistic children and 92 control children , antibodies were assayed by ELISA or immunoblotting methods . ELISA analysis showed a significant increase in the level of MMR antibodies in autistic children . Immunoblotting analysis revealed the presence of an unusual MMR antibody in 75 of 125 (60%) autistic sera but not in control sera . This antibody specificall y detected a protein of 73-75 kD of MMR. This protein band, as analyzed with monoclonal antibodies , was immunopositive for measles hemagglutinin (HA) protein but not for measles nucleoprotein and rubella or mumps viral proteins. Thus the MMR antibody in autistic sera detected measles HA protein, which is unique to the measles subunit of the vaccine. Furthermore, over 90% of MMR antibody-positive autistic sera were also positive for MBP autoantibodies, suggesting a strong association between MMR and CNS autoimmunity in autism. Stemming from this evidence, we suggest that an inappropriate antibody response to MMR, specifically the measles component thereof, might be related to pathogenesis of autism
Children with Autism are prone to autoimmunity
Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders.
Connolly AM , Chez MG , Pestronk A , Arnold ST , Mehta S , Deuel RK .
Departments of Neurology and Pediatrics, Washington University, St. Louis Children's Hospital J Pediatr. 1999 May;134(5):607-13.
OBJECTIVE : Etiologically unexplained disorders of language and social development have often been reported to improve in patients treated with immune-modulating regimens. Here we determined the frequency of autoantibodies to brain among such children. DESIGN: We collected sera from a cohort of children with (1) pure Landau-Kleffner syndrome (n = 2), (2) Landau-Kleffner syndrome variant (LKSV, n = 11), and (3) autistic spectrum disorder (ASD, n = 11). None had received immune-modulating treatment before the serum sample was obtained. Control sera (n = 71) were from 29 healthy children, 22 with non-neurologic illnesses (NNIs), and 20 children with other neurologic disorders (ONDs). We identified brain autoantibodies by immunostaining of human temporal cortex and antinuclear autoantibodies using commercially available kits. RESULTS: IgG anti-brain autoantibodies were present in 45% of sera from children with LKSV, 27% with ASD, and 10% with ONDs compared with 2% from healthy children and control children with NNIs. IgM autoantibodies were present in 36% of sera from children with ASD, 9% with LKSV, and 15% with ONDs compared with 0% of control sera. Labeling studies identified one antigenic target to be endothelial cells. Antinuclear antibodies with titers >/=1:80 were more common in children with ASD and control children with ONDs. CONCLUSION: Children with LKSV and ASD have a greater frequency of serum antibodies to brain endothelial cells and to nuclei than children with NNIs or healthy children. The presence of these antibodies raises the possibility that autoimmunity plays a role in the pathogenesis of language and social developmental abnormalities in a subset of children with these disorders .
Children with Autism are prone to autoimmunity
Antibrain antibodies in children with autism and their unaffected siblings.
Singer HS , Morris CM , Williams PN , Yoon DY , Hong JJ , Zimmerman AW .
Department of Neurology, Johns Hopkins University School of Medicine,
J Neuroimmunol. 2006 Sep;178(1-2):149-55.
Serum autoantibodies to human brain , identified by ELISA and Western immunoblotting, were evaluated in 29 children with autism spectrum disorder (22 with autistic disorder), 9 non-autistic siblings and 13 controls . More autistic subjects than controls had bands at 100 kDa in caudate, putamen and prefrontal cortex (p<0.01) as well as larger peak heights of bands at 73 kDa in the cerebellum and cingulate gyrus. Both autistic disorder subjects and their matched non-autistic siblings had denser bands (peak height and/or area under the curve) at 73 kDa in the cerebellum and cingulate gyrus than did controls (p<0.01). Results suggest that children with autistic disorder and their siblings exhibit differences compared to controls in autoimmune reactivity to specific epitopes located in distinct brain regions.
Thimerosal Induces Autistic Symptoms in Mice prone to Autoimmune diseases
Neurotoxic effects of postnatal thimerosal are mouse strain dependent.
Hornig M , Chian D , Lipkin WI .
Jerome L and Dawn Greene Infectious Disease Laboratory, Department of Epidemiology, Mailman School of Public Health, Columbia University
Mol Psychiatry. 2004 Sep;9(9):833-45
The developing brain is uniquely susceptible to the neurotoxic hazard posed by mercurials. Host differences in maturation, metabolism, nutrition, sex, and autoimmunity influence outcomes. How population-based variability affects the safety of the ethylmercury-containing vaccine preservative, thimerosal, is unknown. Reported increases in the prevalence of autism, a highly heritable neuropsychiatric condition, are intensifying public focus on environmental exposures such as thimerosal. Immune profiles and family history in autism are frequently consistent with autoimmunity. We hypothesized that autoimmune propensity influences outcomes in mice following thimerosal challenges that mimic routine childhood immunizations. Autoimmune disease-sensitive SJL/J mice showed growth delay; reduced locomotion; exaggerated response to novelty; and densely packed, hyperchromic hippocampal neurons with altered glutamate receptors and transporters. Strains resistant to autoimmunity, C57BL/6J and BALB/cJ, were not susceptible. These findings implicate genetic influences and provide a model for investigating thimerosal-related neurotoxicity.
9x increase in Special Education Services in Children who received Hepatitis B Vaccine
Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years
Carolyn Gallagher ; Melody Goodman
Graduate Program in Public Health, Stony Brook University Medical Center, Health Sciences Center, New York, USA
This study investigated the association between vaccination with the Hepatitis B triple series vaccine prior to 2000 and developmental disability in children aged 1-9 years ( n = 1824), proxied by parental report that their child receives early intervention or special education services (EIS). National Health and Nutrition Examination Survey 1999-2000 data were analyzed and adjusted for survey design by Taylor Linearization using SAS version 9.1 software, with SAS callable SUDAAN version 9.0.1. The odds of receiving EIS were approximately nine times as great for vaccinated boys ( n = 46) as for unvaccinated boys ( n = 7), after adjustment for confounders. This study found statistically significant evidence to suggest that boys in United States who were vaccinated with the triple series Hepatitis B vaccine, during the time period in which vaccines were manufactured with thimerosal, were 9x more susceptible to developmental disability than were unvaccinated boys.
HEPATITIS B VACCINATION OF MALE NEONATESAND AUTISM
CM Gallagher, MS Goodman, Graduate Program in Public Health, Stony Brook University Medical Center, Stony Brook, NY
Annals of Epidemiology Vol. 19, No. 9 September 2009: p24
PURPOSE: Universal newborn immunization with hepatitis B vaccine was recommended in 1991; however, safety findings are mixed. The Vaccine Safety Datalink Workgroup reported no association between hepatitis B vaccination at birth and febrile episodes or neurological adverse events. Other studies found positive associations between hepatitis B vaccination and ear infection, pharyngitis, and chronic arthritis; as well as receipt of early intervention/special education services (EIS); in probability samples of U.S. children. Children with autistic spectrum disorder (ASD) comprise a growing caseload for EIS. We evaluated the association between hepatitis B vaccination of male neonates and parental report of ASD . METHODS: This cross-sectional study used U.S. probability samples obtained from National Health Interview Survey 1997–2002 datasets. Logistic regression modeling was used to estimate the effect of neonatal hepatitis B vaccination on ASD risk among boys age 3–17 years with shot records, adjusted for race, maternal education, and two-parent household.
RESULTS: Boys who received the hepatitis B vaccine during the first month of life had 2.94 greater odds for ASD (nZ31 of 7,486; OR Z 2.94; p Z 0.03; 95% CI Z 1.10, 7.90) compared to later- or unvaccinated boys. Non-Hispanic white boys were 61%less likely to have ASD(ORZ0.39; pZ0.04; 95% CIZ0.16, 0.94) relative to non-white boys. CONCLUSION: Findings suggest that U.S. male neonates vaccinated with hepatitis B vaccine had a 3-fold greater risk of ASD; risk was greatest for non-white boys .
Statement of Florida Vaccine Rights and Informed Consent
I. I understand that vaccines are given to protect both the individual and the general population against catching and spreading certain serious infectious diseases. I recognize that reactions to vaccines sometimes do occur. The way that vaccines are given shall conform to recognized standards of medical practice in accordance with U.S. Department of Health and Human Services, Public Health Service’s Recommendations of the Advisory Committee on Immunization Practices (ACIP), and the latest Report of the Committee of Infectious Diseases of the American Academy of Pediatrics (Red Book).
II. I have a right to delay any vaccine until I feel that I am capable of making an informed decision and have been able to assess the benefits, risks, and alternatives. I am aware that prior to school/daycare entry that vaccines are not mandatory.
III. To exercise my right of informed consent, I may use all resources available to me to become more fully informed about vaccine contents, effectiveness, safety, and possible side effects.
Statement of Florida Vaccine Rights and Informed Consent
IV. The Vaccine Information Statement (VIS) must be provided to me before the administration of any vaccine, but I may ask for a copy of any of the VIS at any time before the vaccine appointment date, so that I may have time to review and understand the content. I also may ask to review the vaccine package insert(s) to get more information about the particular vaccine(s), its content(s), effectiveness, contraindications and possible side effects.
V. At any time after a vaccine is administered, I may request a copy of the Vaccine Administration Record (healthcare providers are required to note the edition date of the VIS given to the patient, the date the VIS was given, the name, address and title of the individual who administers the vaccine, the date it was administered, and the vaccine manufacturer and lot number of the vaccine used) from my child’s physician, to be provided within a reasonable amount of time.
Statement of Florida Vaccine Rights and Informed Consent
VI. For school or daycare enrollment, one may be exempt from vaccination for medical or religious (HRS FORM 681) reasons, as stated in Florida Statute 1003.22. Without a legal exemption, I understand that one must have begun a vaccine administration schedule in order to attend daycare or school.
VII. At any time after a vaccine is administered, I may file a VAERS incident report for vaccine reactions, with or without a physician’s approval or signature. I may also review VAERS reported adverse events/surveillance data at: http://vaers.hhs.gov/
VIII. As long as vaccines have been administered in accordance with the guidelines put forth by the CDC and FDA, and the physician has not compromised the rights stated above, by making this informed decision I do not hold the health care provider liable for any potential negative outcome, whether it is from the giving or withholding of any or all vaccines.
Vaccines that are “required”: polio, DTaP, Hep B, MMR, Hib, Chicken pox
Other vaccines are “recommended” by the CDC and Florida DOH, but not “required”
In order to enroll a child in school or daycare, the child must have commenced a schedule to complete vaccines, it is not required that the child is up to date. But a medical practitioner must sign off using a temporary medical exemption, updating the form as additional vaccines are given.
There is no set schedule that must be followed to “catch up” the child.
There is clear wording in the Florida Statute as to who can claim a religious exemption. As I am not a member of the clergy, it would be inappropriate for me to recommend that someone seek the exemption, but I can direct people to information that explains elegibility for the exemption. For a better understanding as to what the law says about the Religious Exemption, detailed information, including the actual wording of the statute and the Florida Supreme Court's 1998 ruling on the statute , can be found at www.know-vaccines.org .
My Personal Recommendations Regarding Vaccines
Unless there are certain circumstances (mom Hep B+, early day-care), consider waiting until at least 6 months old before giving any vaccine.
Do not give more then 1 new vaccine at a time so if there is a reaction, it may be easier to figure out what it was due to.
Consider giving more than 1 vaccine at a time for 3 rd and subsequent doses for a particular vaccine, if there were no negative reactions to the first 2 doses.
Wait at least 3 months in between live virus vaccines (M,M,R and Varicella). Consider delaying these until 2 years old unless high incidence in community.
Do not vaccinate when sick or until 2 weeks after illness resolved.
Do not vaccinate when there is signs of over-inflammation such as active wheeze, eczema or allergy.
Consider waiting until 2 years old, or not vaccinating at all, children who are high risk, or with significant family history, of auto-immune or hyper-inflammatory conditions.
Give vitamin C, zinc and Echinacea from 3 days before until 3 days after any vaccines, and vitamin A the day before, of, and after (dosing according to “On the first signs of illness article” on the Medical Topics section at www.wholisticpeds.com .
Get IgG titers before boosters in year prior to starting Kindergarten, only give vaccine if not immune at that time (? Tetanus “legality”).
* if MMR Triple vaccine is the only vaccine available
** only if there are negative IgG titers for one or more components and MMR Triple Vaccine is only option available.
*** minimum of 1 months in between any 2 doses
check IgG titers for all children in the 12 months prior to starting Kindergarten for Measles, Mumps and Rubella. If not protected for one of the viruses and only MMR available, give MMR #2 at least 1 months after Triple or any of the single components given. If single virus available, give what is lacking, 1 month between each vaccine.