The Healing Brain A Scientific Reader Robert Ornstein and Charles Swencionis, (editors)

The Healing Brain

A Scientific Reader

Robert Ornstein and

Charles Swencionis,

(editors)

精神神經免疫學 Psycho neuro immunology

Candace Pert

R e c e p t o r s 感受器

Receptors for External Opiates (Exogenous ligand) morphine heroin opium codeine

Endogenous Ligands (internal opiates) Beta-endorphin http://micro.magnet.fsu.edu/micro/gallery/endorphin/endorph2.jpg

Beta-endorphin

Peptide produced by nerve cells in the brain http://pdelagrange.free.fr/povlab/demopic/neurons.jpg Neuropeptides

Peptide produced by nerve cells

in the brain

Neuropeptides Opiate receptors 20,000 amino acids 20 amino acids 阿片制劑感受器

Neuropeptides

Opiate receptors

20,000 amino acids

突觸 感受器 Synapse Receptors

The Biochemistry of Emotions

Hypothalamus ( 丘腦下部 ) (homeostasis ) Pituitary ( 垂體 ) (regulates hormone) Amygdala ( 杏仁核 ) (fear) Emotions 情緒

Hypothalamus

( 丘腦下部 )

(homeostasis )

Pituitary

( 垂體 )

(regulates hormone)

Opiate receptors in limbic system

Hypothalamus 丘腦下部 40-fold higher with opiate receptors Walter B Cannon

Hypothalamus

丘腦下部

40-fold higher with

opiate receptors

Many of the neuropeptides are hormones produced by the glands and not by nerve cells, e.g. insulin Pituitary 腦垂體 胰島素

Many of the neuropeptides are

hormones produced by the glands

and not by nerve cells, e.g. insulin

Hormones stores in one place of the body and travel to its receptors in other parts of the body http://micro.magnet.fsu.edu/micro/gallery/hormones/hormone.jpg

Hormones stores in

one place of the

body and travel to its

receptors in other

parts of the body

夷島素 Insulin Insulin secreted by pancreas BUT—insulin also found to be made and stored in the brain In amygdala and hypothalamus 胰島素

Insulin secreted by pancreas

BUT—insulin also found to be made and stored in the brain

In amygdala and hypothalamus

Nodal points Points that receive a lot of emotional modulation We have found that for virtually all the senses for which we know the entry area, the spot is always a nodal point for neuropeptides receptors

Points that receive a lot of emotional modulation

We have found that for virtually all the senses for which we know the entry area, the spot is always a nodal point for neuropeptides receptors

Angiotensin Mediates thirst Found in brain and in kidney 血管緊張素

Mediates thirst

Found in brain and in kidney

CCK Found in brain, gut and spleen Food satiety – makes you not want to eat

Found in brain, gut and spleen

Food satiety – makes you not want to eat

From esophagus to the large intestine – all lined with nerve, neuropeptides opiate receptors

From esophagus to the large intestine – all lined with nerve, neuropeptides opiate receptors

免疫系統 內分泌系統 神經系統

Cells in immune system Monocytes 免疫系統 單核細胞

The new discovery I want to emphasize here is that every neuropeptide receptor that we have looked for is also on the human monocytes.

The new discovery I want to emphasize here is that every neuropeptide receptor that we have looked for is also on the human monocytes.

These emotion-affecting biochemicals [neuropeptides] actually appear to control the routing and migration of monocytes.

These emotion-affecting biochemicals [neuropeptides]

actually appear to control the routing and migration of monocytes.

The cells of the immune system not only have receptors for these various neuropeptides, … they also make the neuropeptides themselves.

The cells of the immune system not only have receptors for these various neuropeptides, … they also make the neuropeptides themselves.

多謝出席 下次請早 祝各位強腦健體