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This study uses Relevance Vector Machine (RVM) regression to develop a probabilistic model for the average horizontal component of 5%-damped earthquake response spectra. Unlike conventional models, the proposed approach does not require a functional form, and constructs the model based on a set predictive variables and a set of representative ground motion records. The RVM uses Bayesian inference to determine the confidence intervals, instead of estimating them from the mean squared errors on the training set. An example application using three predictive variables (magnitude, distance and fault mechanism) is presented for sites with shear wave velocities ranging from 450 m/s to 900 m/s. The predictions from the proposed model are compared to an existing parametric model. The results demonstrate the validity of the proposed model, and suggest that it can be used as an alternative to the conventional ground motion models. Future studies will investigate the effect of additional predictive variables on the predictive performance of the model.