Hemoglobinuria: red-brown color of urine due to free hemoglobin and methamoglobin.
Decreased Heptaglobin level: it is a alpha-2-globin produced in the liver. It binds free hemoglobin thus level is reduced in hemolysis.
Hemosidrinuria: it reflects extensive hemolysis for a prolonged period of time. When hemoglobin is filtered by nephron, proximal tubular cells metabolize hemoglobin and iron accumulate in the cells. Cells then exfoliate in the urine and iron can be detected by Prussian blue reaction.